The Diabetic Food Pyramid
Blood Pressure Drugs No Help for Diabetes Studies: Statins, Fibrates to Lower Fats, Cholesterol and Blood Pressure Do Not Reduce Heart Attack Risk in Diabetics (Source: Health News: CBSNews.com) miR-375 enhances palmitate-induced lipoapoptosis in insulin-secreting NIT-1 cells by repressing myotrophin (V1) protein expression. Authors: Li Y, Xu X, Liang Y, Liu S, Xiao H, Li F, Cheng H, Fu Z
Lipoapoptosis of pancreatic beta cells caused by elevated circulating free fatty acids (FFAs) has now been recognized to be a pivotal factor contributing to beta cellular dysfunction and beta-mass lose in type 2 diabetes. Although recent studies suggested an important role for the ceramide pathway in the late destructive phase of lipid overload in the pancreatic beta cells, the overall underlying mechanisms leading to lipoapoptosis, however, remained poorly understood. mir-375 was recently characterized to be a pancreatic islet-specific miRNA implicated in the regulation of insulin secretion and beta-mass turnover. In the present study we further examined its effect on palmitate-induced lipoapoptosis in NIT-1 cells, a NOD... Factors Influencing Driving Status in an Older Latino Population. - Segal-Gidan F, Varma R, Salazar X, Mack WJ. This study uses cross-sectional data from 421 elderly Latino particip... (Source: SafetyLit: All (Unduplicated)) Diabetes Heart Treatments May Do Harm Three treatment strategies that doctors had expected would prevent heart attacks among people with Type 2 diabetes have proven to be ineffective or even harmful. (Source: NYT > Health) Novartis drugs fail to help high-risk patients ATLANTA (Reuters) - The Novartis diabetes drug Starlix failed to reduce progression to the disease or cut down on serious heart problems in patients at high risk for both diabetes and heart disease, according to a large study released on Sunday. (Source: Reuters: Health) No heart benefit seen with fibrates in diabetics ATLANTA (Reuters) - Adding a triglyceride lowering drug to cholesterol fighting statins provided no additional protection from heart attack, stroke and death from heart disease in patients with Type 2 diabetes, according to data from a large study. (Source: Reuters: Health)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Get the very latest Swine Flu news via the MedWorm <b><a href="http://www.medworm.com/rss/search.php?qu=%2Bswine+%2B%28influenza+flu%29&t=Swine+Flu&f=infectiousdiseases&r=Any&o=d" target ="_self">Swine Flu RSS news feed</a></b> - updated hourly from thousands of authoritative health and news sources.</p></div> NAVIGATOR Off Course to Diabetes Prevention With Valsartan, Nateglinide In a population with impaired glucose tolerance and CV disease or risk factors, the angiotensin receptor blocker had a slight effect and the short-acting insulin secretagogue had no favorable impact on progression to diabetes; neither drug prevented cardiovascular events. Heartwire (Source: Medscape Today Headlines) ACCORD: Fenofibrate No Benefit to Statin Therapy in High-Risk Diabetic Patients The findings do not support the use of combination fibrate-statin therapy to reduce cardiovascular risk in the majority of patients with type 2 diabetes who are at high risk for cardiovascular disease, according to the ACCORD investigators. Heartwire (Source: Medscape Today Headlines) ACC: Close Lipid and BP Control Fail in Diabetes (CME/CE) ATLANTA (MedPage Today) -- Intensive blood pressure and lipid management does little against elevated cardiovascular risk in diabetes, according to results from the ACCORD study, again proving lower isn't always better. (Source: MedPage Today Cardiovascular) ACCORD: Fenofibrate no benefit to statin therapy in high-risk diabetic patients The findings do not support the use of combination fibrate-statin therapy to reduce cardiovascular risk in the majority of patients with type 2 diabetes who are at high risk for cardiovascular...
For complete story visit theheart.org. (Source: theHeart.org) NAVIGATOR off course to diabetes prevention with valsartan, nateglinide In a population with impaired glucose tolerance and CV disease or risk factors, the angiotensin receptor blocker had a slight effect and the short-acting insulin secretagogue had no favorable impact...
For complete story visit theheart.org. (Source: theHeart.org)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Get the very latest Swine Flu news via the MedWorm <b><a href="http://www.medworm.com/rss/search.php?qu=%2Bswine+%2B%28influenza+flu%29&t=Swine+Flu&f=infectiousdiseases&r=Any&o=d" target ="_self">Swine Flu RSS news feed</a></b> - updated hourly from thousands of authoritative health and news sources.</p></div> EHSI: New High-Level Telemedicine Study Launched Emerging Healthcare Solutions, Inc. (Pink Sheets: EHSI) was pleased on learning the news that Intel, The Mayo Clinic and GE Healthcare have launched a new initiative to study the care and cost benefits of home-based telemedicine for elderly patients with chronic illnesses. Emerging Healthcare Solutions has licensed a cutting-edge mobile telemedicine platform from Telemedicus, Inc., which the Company is currently developing for marketing... (Source: Health News from Medical News Today) New Food Labelling Guidelines - Diabetes UK The Food Standards Agency (FSA) has agreed to the implementation of a single approach to front-of-pack (FOP) nutrition labelling that it says will best help consumers make healthier choices when they buy food. Food businesses will be encouraged to use all three elements found by independent research to help UK consumers interpret nutritional information: traffic light colours (red, amber and green), text (high, medium or low) and percentage Guideline Daily Amounts (% GDAs)... (Source: Health News from Medical News Today) EHSI: New High-Level Telemedicine Study Launched Emerging Healthcare Solutions, Inc. (Pink Sheets: EHSI) was pleased on learning the news that Intel, The Mayo Clinic and GE Healthcare have launched a new initiative to study the care and cost benefits of home-based telemedicine for elderly patients with chronic illnesses. Emerging Healthcare Solutions has licensed a cutting-edge mobile telemedicine platform from Telemedicus, Inc... (Source: Seniors / Aging News From Medical News Today) New Food Labelling Guidelines - Diabetes UK The Food Standards Agency (FSA) has agreed to the implementation of a single approach to front-of-pack (FOP) nutrition labelling that it says will best help consumers make healthier choices when they buy food... (Source: Nutrition/Agriculture News From Medical News Today) ACCORD: Intensive BP, combined lipid therapies do not help adults with diabetes (NIH/National Heart, Lung and Blood Institute) Lowering blood pressure to normal levels -- below currently recommended levels -- did not significantly reduce the combined risk of fatal or nonfatal cardiovascular disease events in adults with type 2 diabetes who were at especially high risk for cardiovascular disease events, according to new results from the landmark Action to Control Cardiovascular Risk in Diabetes (ACCORD) clinical trial. (Source: EurekAlert! - Medicine and Health)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Get the very latest Swine Flu news via the MedWorm <b><a href="http://www.medworm.com/rss/search.php?qu=%2Bswine+%2B%28influenza+flu%29&t=Swine+Flu&f=infectiousdiseases&r=Any&o=d" target ="_self">Swine Flu RSS news feed</a></b> - updated hourly from thousands of authoritative health and news sources.</p></div> UF researcher urges caution in reducing blood pressure in patients with diabetes, coronary disease (University of Florida) Systolic blood pressure levels between 130 and 140 appear to be the most healthful for patients with both diabetes and coronary artery disease, according to findings from the American College of Cardiology's 59th annual scientific session in Atlanta. (Source: EurekAlert! - Medicine and Health) Intensive blood pressure, combined lipid therapies do not help adults with diabetes, study finds Lowering blood pressure to normal levels -- below currently recommended levels -- did not significantly reduce the combined risk of fatal or nonfatal cardiovascular disease events in adults with type 2 diabetes who were at especially high risk for cardiovascular disease events, according to new results. (Source: ScienceDaily Headlines) Caution urged in reducing blood pressure in patients with diabetes, coronary disease Systolic blood pressure levels between 130 and 140 appear to be the most healthful for patients with both diabetes and coronary artery disease, according to new findings. (Source: ScienceDaily Headlines) Gardening: It's Good For Your Health Daily physical activity is a prerequisite for good health. Gardening is an excellent way to be physically active while growing healthy vegetables and fruits, as well as beautiful flowers. Active people are less likely than inactive people to be obese or have high blood pressure, type 2 diabetes, osteoporosis, coronary artery disease, stroke, depression, colon cancer and premature death. (Source: Cancercompass News: Breast Cancer) Diabetes Medications Related to an Increased Risk of Falls and Fall-Related Morbidity in the Elderly. - Berlie HD, Garwood CL. OBJECTIVE: To review literature regarding the effect of diabetes medications as a contributing risk for falls and fall-related morbidity in elderly patients with type 2 diabetes. DATA SOURCES: Primary literature was identified through PubMed MEDLINE (19... (Source: SafetyLit: All (Unduplicated))<div id="medworm"><p><b><i>MedWorm Message:</i></b> Get the very latest Swine Flu news via the MedWorm <b><a href="http://www.medworm.com/rss/search.php?qu=%2Bswine+%2B%28influenza+flu%29&t=Swine+Flu&f=infectiousdiseases&r=Any&o=d" target ="_self">Swine Flu RSS news feed</a></b> - updated hourly from thousands of authoritative health and news sources.</p></div> The relationship between the stipulated tempo step test, daily activity ability and gait time in elderly. - Shin S, Demura S. This study is aimed at examining the relationship between stipulated tempo step tests, daily activity ability, and gait time. One hundred and thirty healthy elderly women performed the step test in which they stepped in place for 20s while matching a me... (Source: SafetyLit: All (Unduplicated)) National Program to Eliminate Diabetes-Related Disparities in Vulnerable Populations Funding Opportunity Number: CDC-RFA-DP10-1001 Opportunity Category: DiscretionaryFunding Instrument Type: Cooperative AgreementCategory of Funding Activity: HealthCFDA Number: 93.283Eligible Applicants Others (see text field entitled "Additional Information on Eligibility" for clarification)Agency Name HHS-CDC (Source: Grants.gov) Celiac disease in Brazilian patients: associations, complications and causes of death. Forty years of clinical experience Conclusions - This experience is similar to those described in the world literature. Celiac disease presents the same characteristics independently of the geographic region. We recommend periodic evaluations, from childhood, independent of the duration of the diet. The key is to establish an interval between evaluations.CONTEXTO: A doença celíaca é uma enfermidade multissistêmica e autoimune que pode se manifestar em qualquer idade, em indivíduos geneticamente predispostos. OBJETIVO: Identificação das associações, complicações e causas de morte em pacientes brasileiros após longo período de acompanhamento. MÉTODOS: Foram estudados retrospectivamente 157 pacientes, 23 adolescentes e 134 adultos, 79,6% do sexo feminino e 20,4% do masculino, 75,8% ao diagnóstico e 24,2% em diet... Gastrointestinal and liver side effects of drugs in elderly patients It is expected that the percentage of people >60 years of age will be 22% worldwide by the year 2050. Multi-morbidity and poly-pharmacy are common in individuals during old age, while adverse drug reactions are at least twice as common in the elderly compared to younger adults. Publications related to drug side effects are rather rare in this age group since most clinical trials exclude patients >75?80 years of age. Gastrointestinal adverse drug reactions studied in the elderly include non-steroidal anti-inflammatory drugs (NSAIDs) and anticoagulant-induced gastrointestinal tract mucosal injuries. Malabsorption, diarrhoea and constipation are common side effects of laxatives, antibiotics, anticholinergics and calcium channel blockers. Drug (amoxycilin/clavulanic acid, isoniazide, nitrofu... Young Type 2 diabetics have impaired mitochondrial response to exercise Obese individuals who develop Type 2 diabetes early in life are unable to increase their maximal oxygen consumption in response to chronic exercise, which is likely to be due to mitochondrial abnormalities, say investigators. (Source: MedWire News - Diabetes)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Get the very latest Swine Flu news via the MedWorm <b><a href="http://www.medworm.com/rss/search.php?qu=%2Bswine+%2B%28influenza+flu%29&t=Swine+Flu&f=infectiousdiseases&r=Any&o=d" target ="_self">Swine Flu RSS news feed</a></b> - updated hourly from thousands of authoritative health and news sources.</p></div> The characteristics of elderly burns in Shanghai This study aims to analyse the epidemiologic characteristics of severe burn in the elderly in Shanghai and to discusses a possible prevention programme for this population.Methods: A retrospective review of all medical records of elderly patients (aged 60 and older) admitted with acute burns to the Burn Center of the RuiJin Hospital between January 1996 and December 2004 was carried out. Patient demographics, etiology of burn, mechanism of injury, burn extent, anatomical areas burned, number of operations, and outcomes were reviewed.Results: A total of 201 (5.8% of hospitalised patients) elderly patients (mean age (±SD) of 69.3±7.1 years (range 60?90 years)) were admitted. Majority of the patients were men (62.2%) and the most common etiologies were flames (52.7%) and scalds (39.8%). T... Trapeze-flap plasty: Effective method for postburn neck contracture elimination Abstract: The new method for postburn neck contracture management is presented. The method is found to be most effective when using the local flap procedures on patients who cannot undergo complex and long surgical procedures that are aimed at both contracture elimination and neck skin restoration (children, elderly patients, patients with inadequate donor sites, and patients with cosmetically acceptable scar appearance). The method consists of the opposite transposition of trapezoid scar-fascial flaps which are prepared one on each antero-lateral neck surface. Both flaps include scars, fat, platysma and deep cervical fascia. As a result of the trapeze-flap plasty, the anterior surface of the neck is lengthened approximately by 100?200%, the contracture is eliminated and mentocervical an... Diabetes Experts Call For Early, Integrated Treatment Approach To Help Prevent Complications And Improve Patient Outcomes Results from a new online survey of more than 300 practicing endocrinologists and family medicine physicians1 show that a large majority of physicians (83 percent)1 indicated that using a team of specialists early in the course of type 2 diabetes (T2D) treatment can help prevent serious T2D-related complications. However, more than nine out of 10 physicians (93 percent)1 surveyed do not believe their peers are using this team approach. The online survey was supported by Boehringer Ingelheim Pharmaceuticals, Inc. and conducted by Sermo... (Source: Health News from Medical News Today) Diabetes Experts Call For Early, Integrated Treatment Approach To Help Prevent Complications And Improve Patient Outcomes Results from a new online survey of more than 300 practicing endocrinologists and family medicine physicians1 show that a large majority of physicians (83 percent)1 indicated that using a team of specialists early in the course of type 2 diabetes (T2D) treatment can help prevent serious T2D-related complications... (Source: Diabetes News From Medical News Today) Knee replacement in elderly patients shown to improve balance Total knee replacement (TKR) successfully relieves pain and improves function in patients with advanced knee arthritis, according to a new study. (Source: ScienceDaily Headlines)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Get the very latest Swine Flu news via the MedWorm <b><a href="http://www.medworm.com/rss/search.php?qu=%2Bswine+%2B%28influenza+flu%29&t=Swine+Flu&f=infectiousdiseases&r=Any&o=d" target ="_self">Swine Flu RSS news feed</a></b> - updated hourly from thousands of authoritative health and news sources.</p></div> Exploring Diabetes' Link To Eating Disorders Diabetics, under the gun to better manage their disease by controlling their food intake and weight, may find themselves in the sticky wicket of needing treatment that makes them hungry, researchers said. Attempts to maintain healthy blood sugar levels and prevent weight gain may suggest an eating disorder when the disease and its treatment are to blame, said Dr. Deborah Young-Hyman, pediatric psychologist at the Medical College of Georgia's Georgia Prevention Institute... (Source: Health News from Medical News Today) TaiGen Announces Nemonoxacin (TG-873870) Once-A-Day Oral Dosing In Diabetic Foot Infection Met Primary Endpoints TaiGen Biotechnology Co., Ltd. announced the Phase II trial of nemonoxacin (TG-873870) in Diabetic Foot Infection (DFI) with once-a-day dosing met the primary endpoints and showed promising clinical efficacy and good tolerability. Nemonoxacin is a novel non-fluorinated quinolone that has a broad spectrum of activity against gram-positive and gram-negative bacteria and atypical pathogens. Importantly, nemonoxacin possesses activities against Methicillin-Resistant Staphylococcus aureus (MRSA) and vancomycin-resistant pathogens... (Source: Health News from Medical News Today) Exploring Diabetes' Link To Eating Disorders Diabetics, under the gun to better manage their disease by controlling their food intake and weight, may find themselves in the sticky wicket of needing treatment that makes them hungry, researchers said. Attempts to maintain healthy blood sugar levels and prevent weight gain may suggest an eating disorder when the disease and its treatment are to blame, said Dr... (Source: Diabetes News From Medical News Today) TaiGen Announces Nemonoxacin (TG-873870) Once-A-Day Oral Dosing In Diabetic Foot Infection Met Primary Endpoints TaiGen Biotechnology Co., Ltd. announced the Phase II trial of nemonoxacin (TG-873870) in Diabetic Foot Infection (DFI) with once-a-day dosing met the primary endpoints and showed promising clinical efficacy and good tolerability. Nemonoxacin is a novel non-fluorinated quinolone that has a broad spectrum of activity against gram-positive and gram-negative bacteria and atypical pathogens... (Source: Diabetes News From Medical News Today) Changing patterns in health behaviors and risk factors related to cardiovascular disease among american indians and alaska natives. CONCLUSIONS: Diabetes, obesity, and hypertension and their associated risk factors should be studied further among urban, rural, and reservation American Indian and Alaska Native populations, and effective primary and secondary prevention efforts are critical.
PMID: 20220114 [PubMed - in process] (Source: American Journal of Public Health)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Get the very latest Swine Flu news via the MedWorm <b><a href="http://www.medworm.com/rss/search.php?qu=%2Bswine+%2B%28influenza+flu%29&t=Swine+Flu&f=infectiousdiseases&r=Any&o=d" target ="_self">Swine Flu RSS news feed</a></b> - updated hourly from thousands of authoritative health and news sources.</p></div> The Body's Anticipation Of A Meal Can Be A Diabetes Risk Factor Alterations in our response to the taste or smell of food may be another culprit responsible for Type 2 diabetes, according to scientists at Duke University Medical Center who have identified the specific mechanism in human specimens and in mice. When we anticipate or smell a meal, the parasympathetic nervous system triggers salivation and increases insulin production in response to the expectation that glucose will be entering the blood stream. "We think this parasympathetic response is potentially important in type 2 diabetes," said Vann Bennett, the James B... (Source: Health News from Medical News Today) Multiple Benefits To Surgery Reported For Patients With Advanced Osteoarthritis Total knee replacement (TKR) successfully relieves pain and improves function in patients with advanced knee arthritis, according to a study presented at the 2010 Annual Meeting of the American Academy of Orthopaedic Surgeons (AAOS). The surgery also significantly improves dynamic balance among elderly patients. Impaired balance and increased tendency to fall are common complaints among the elderly suffering from severe osteoarthritis (worn cartilage)... (Source: Health News from Medical News Today) Cutting Obesity In Black, Latino New Yorkers A $6 million grant from the National Heart, Lung and Blood Institute (NHLBI) has funded the creation of ORBIT: Obesity Related Behavioral Intervention Trials to focus on reducing obesity and obesity-related deaths in New York City's African-American and Latino communities. "African-Americans and Latinos have been disproportionately affected by the obesity epidemic, and its related risks for diabetes and heart disease," says Dr. Mary Charlson, the center's director, the William T... (Source: Health News from Medical News Today) The Body's Anticipation Of A Meal Can Be A Diabetes Risk Factor Alterations in our response to the taste or smell of food may be another culprit responsible for Type 2 diabetes, according to scientists at Duke University Medical Center who have identified the specific mechanism in human specimens and in mice... (Source: Diabetes News From Medical News Today) Multiple Benefits To Surgery Reported For Patients With Advanced Osteoarthritis Total knee replacement (TKR) successfully relieves pain and improves function in patients with advanced knee arthritis, according to a study presented at the 2010 Annual Meeting of the American Academy of Orthopaedic Surgeons (AAOS). The surgery also significantly improves dynamic balance among elderly patients... (Source: Seniors / Aging News From Medical News Today)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Get the very latest Swine Flu news via the MedWorm <b><a href="http://www.medworm.com/rss/search.php?qu=%2Bswine+%2B%28influenza+flu%29&t=Swine+Flu&f=infectiousdiseases&r=Any&o=d" target ="_self">Swine Flu RSS news feed</a></b> - updated hourly from thousands of authoritative health and news sources.</p></div> Diabetes educators play key role If you have diabetes or are at risk, take advantage of diabetes education. (Source: MayoClinic.com Full Feed) A Review of Methods Used in Long-Term Cost-Effectiveness Models of Diabetes Mellitus Treatment (Source: PharmacoEconomics) 'Mixed picture' in major review of children's care services CARE services for children and elderly people in Scotland must improve, experts say. (Source: Scotsman.com News - Health) [Drug therapy for pain associated with osteoporotic fractures and subsequent conditions.] Authors: Müller N
Patients suffering from pain caused by osteoporotic fracture most want pain reduction and the ability to live independently. Age, co-morbidity and co-medication are individual factors which can interfere with drug therapy. Relevant factors for planning and applying drug therapy for pain reduction are identified by literature review in correlation with clinical experience. Pitfalls are numerous and complex. Drug therapy has to be performed and monitored carefully. Strategies for risk reduction are outlined and clarified by examples. Good and safe pain reduction in elderly patients suffering from osteoporotic fractures usually depends on a transdisciplinary regimen.
PMID: 20225128 [PubMed - as supplied by publisher] (Source: Der Orthopade) Short Term High-Intensity Interval Training (HIT) As Effective As Moderate Long Term Endurance Exercise, Study The excuse that there is not enough time to exercise effectively is beginning to wear thin according to evidence from a study by scientists in Canada who found that short term high-intensity interval training (HIT) can deliver in significantly less time the same health benefits as moderate long term "endurance" training... (Source: Diabetes News From Medical News Today)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Get the very latest Swine Flu news via the MedWorm <b><a href="http://www.medworm.com/rss/search.php?qu=%2Bswine+%2B%28influenza+flu%29&t=Swine+Flu&f=infectiousdiseases&r=Any&o=d" target ="_self">Swine Flu RSS news feed</a></b> - updated hourly from thousands of authoritative health and news sources.</p></div> Microalbuminuria in hepatitis C-genotype 4: Effect of pegylated interferon and ribavirin. CONCLUSION: HCV affected the development of microalbuminuria independent of diabetes or cryoglobulinemia. Combination therapy of pegylated interferon-ribavirin had a positive effect in reducing microalbuminuria.
PMID: 20222166 [PubMed - in process] (Source: World Journal of Gastroenterology : WJG) Antepartum and Intrapartum Risk Factors for Neonatal Encephalopathy at Term In conclusion, 44% of cases of NE following term deliveries can be attributed to a combination of antepartum and intrapartum variables.[...]© Thieme Medical PublishersGet connected:Table of contents | Abstract | Full text (Source: American Journal of Perinatology) Pilates method in personal autonomy, static balance and quality of life of elderly females Conclusion: The Pilates method can offer significant improvement in personal autonomy, static balance and quality of life. (Source: Journal of Bodywork and Movement Therapies) Carrot-And-Stick Health Plans Aim to Cut Costs Kaiser Health News article tells how workers at a Portland, Ore., steel mill soon will be able to pick a new type of insurance that offers free care for some illnesses, such as diabetes or depression, but requires hefty extra fees for treatments deemed overused, including knee replacements, hysterectomies and heart bypass surgery. (Source: News stories via the Rural Assistance Center) Understanding suicide in the elderly. - Zanni GR, Wick JY. One suicide occurs every 16 minutes. Intentionally killing oneself is distinctly human; other species don't commit suicide. Suicide is an exceedingly complex phenomenon stemming from intolerable stress and the inability to cope. Elders tend to plan their s... (Source: SafetyLit: All (Unduplicated))<div id="medworm"><p><b><i>MedWorm Message:</i></b> Get the very latest Swine Flu news via the MedWorm <b><a href="http://www.medworm.com/rss/search.php?qu=%2Bswine+%2B%28influenza+flu%29&t=Swine+Flu&f=infectiousdiseases&r=Any&o=d" target ="_self">Swine Flu RSS news feed</a></b> - updated hourly from thousands of authoritative health and news sources.</p></div> Patient Money: Finding the Right Care for the Elderly Some ailing parents might be able to live at home or with their children, but care for a parent with dementia can be extremely expensive. (Source: NYT > Health) Subclinical thyroid dysfunction does not affect one-year mortality in elderly patients after hip fracture: A prospective longitudinal study Abstract: Mortality after hip fractures in the elderly is one of the most important patient outcome measures. Subclinical thyroid dysfunction is common in the elderly population. This is a prospective study of 131 elderly patients with a mean (SD) age of 82.0 (8.9) years (range: 61?94) admitted consecutively to our trauma unit. The aim of the study was to determine the prevalence of subclinical thyroid dysfunction in an elderly cohort of patients with hip fracture and to determine if this affects the one-year mortality.There were three times more women (n=100) than men (n=31) in this cohort. All patients underwent surgical treatment for the hip fracture. The prevalence of subclinical hypothyroidism (TSH>5.5mU/L) was 15% (n=20) and of subclinical hyperthyroidism (TSH (Source: Injury) Different stabilisation techniques for typical acetabular fractures in the elderly?A biomechanical assessment Conclusions: We conclude that the plate fixation by positioning of periarticular long screws as well as the multidirectional positioning of interlocking screws account for the most sufficient fracture stabilisation of ACPHTFs under experimental conditions. (Source: Injury) Acute renal dysfunction following hip fracture Abstract: We investigated the incidence, risk factors and outcome of acute renal dysfunction (ARD) in patients with a fractured neck of femur.170 consecutive patients were prospectively included in the Scottish Hip Fracture Audit database and retrospectively analysed. Historically, lack of consensus definition has hindered accurate reporting of ARD. ARD was defined using the ?RIFLE? criteria.27 patients (16%) developed ARD. Risk factors were male sex, vascular disease, hypertension, diabetes, chronic kidney disease and pre-morbid use of nephrotoxic medications (p (Source: Injury) Clinical characteristics and long-term mortality of occult hip fracture elderly patients Abstract: Background and objective: Occult hip fractures (OHF) occur in a minute population of patients. Diagnosis is made via magnetic resonance imaging (MRI) or alternatively via bone scan. Very little is known about the clinical characteristics of OHF patients. Our aim was to characterize the clinical and long-term survival of OHF in elderly patients and to determine if a certain subgroup of patients would benefit from an MRI investigation following normal or equivocal radiography.Methods: Twenty-nine OHF patients diagnosed by a bone scan during 1995?2004 were compared with a control group of 94 randomly chosen hip fractured patients diagnosed by plain radiography in the same hospital and during the same period.Results: Mean age, women/men ratio, place of residence, comorbidities, cog...<div id="medworm"><p><b><i>MedWorm Message:</i></b> Get the very latest Swine Flu news via the MedWorm <b><a href="http://www.medworm.com/rss/search.php?qu=%2Bswine+%2B%28influenza+flu%29&t=Swine+Flu&f=infectiousdiseases&r=Any&o=d" target ="_self">Swine Flu RSS news feed</a></b> - updated hourly from thousands of authoritative health and news sources.</p></div> A randomised clinical trial comparing minimally invasive surgery to conventional approach for endoprosthesis in elderly patients with hip fractures Conclusion: Based on the results of the present study, we cannot recommend the use of a minimally invasive approach over a standard approach in the implantation of a cemented endoprosthesis. (Source: Injury) Are histological alterations observed in the gallbladder precancerous lesions? CONCLUSION: The results of this study suggest that there could be an association between some histological alterations of gallbladder and cancer, and they also suggest that the metaplasia-dysplasia-carcinoma sequence could in fact be true in the case of gallbladder cancer. Nevertheless, further studies directed towards a perfect understanding of gallbladder carcinogenesis are required. (Source: Clinics) Role of Calcium-independent Phospholipase A2{beta} in High Glucose-induced Activation of RhoA, Rho Kinase, and CPI-17 in Cultured Vascular Smooth Muscle Cells and Vascular Smooth Muscle Hypercontractility in Diabetic Animals [Signal Transduction] Previous studies suggest that high glucose-induced RhoA/Rho kinase/CPI-17 activation is involved in diabetes-associated vascular smooth muscle hypercontractility. However, the upstream signaling that links high glucose and RhoA/Rho kinase/CPI-17 activation is unknown. Here we report that calcium-independent phospholipase A2β (iPLA2β) is required for high glucose-induced RhoA/Rho kinase/CPI-17 activation and thereby contributes to diabetes-associated vascular smooth muscle hypercontractility. We demonstrate that high glucose increases iPLA2β mRNA, protein, and iPLA2 activity in a time-dependent manner. Protein kinase C is involved in high glucose-induced iPLA2β protein up-regulation. Inhibiting iPLA2β activity with bromoenol lactone or preventing its expression by g... Table of Contents Escitalopram and Recovery of Cognition in Elderly Stroke PatientsCitalopram Shows Negative Effects in Patients With DRI and DepressionValproic Acid and AspirinLack of Sertraline Efficacy for Depression in AD PatientsAntipsychotic Prescribing Patterns and Outcomes for Delirium TreatmentImproved Cognition in AD Patients With SouvenaidCombination Donepezil and Intensive Cognitive RehabilitationNew Collaboration to Investigate GRNOPC1 for ADDuodenal Levodopa Infusion Improves Cognition in PD PatientNew Olanzapine WarningsNew Safety LabelingNew Approval (Source: The Brown University Geriatric Psychopharmacology Update) Switch to insulin therapy does not reduce rate of UTIs in Type 2 diabetics There is no evidence that switching from oral treatment to insulin therapy reduces the high rate of urinary tract infections in patients with Type 2 diabetes, say researchers. (Source: MedWire News - Diabetes)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Get the very latest Swine Flu news via the MedWorm <b><a href="http://www.medworm.com/rss/search.php?qu=%2Bswine+%2B%28influenza+flu%29&t=Swine+Flu&f=infectiousdiseases&r=Any&o=d" target ="_self">Swine Flu RSS news feed</a></b> - updated hourly from thousands of authoritative health and news sources.</p></div> Better to Start Metformin Early (CME/CE, with audio) For newly diagnosed type 2 diabetes, waiting until lifestyle measures fail before starting metformin may jeopardize the long-term efficacy of the drug, a large clinical database analysis showed. (Source: MedPage Today Primary Care) "Mixed picture" for stretched care services RISING demand for care of children and the elderly in Scotland is leading to patchy service provision, according to a report. (Source: Scotsman.com News - Health) 'Mixed picture' for stretched care services RISING demand for care of children and the elderly in Scotland is leading to patchy service provision, according to a report. (Source: Scotsman.com News - Health) Mimetics of hormetic agents: stress-resistance triggers. Authors: Sonneborn JS
Mimetics of hormetic agents offer a novel approach to adjust dose to minimize the risk of toxic response, and maximize the benefit of induction of at least partial physiological conditioning. Nature selected and preserved those organisms and triggers that promote tolerance to stress. The induced tolerance can serve to resist that challenge and can repair previous age, disease, and trauma damage as well to provide a more youthful response to other stresses. The associated physiological conditioning may include youthful restoration of DNA repair, resistance to oxidizing pollutants, protein structure and function repair, improved immunity, tissue remodeling, adjustments in central and peripheral nervous systems, and altered metabolism. By elucidating common pathways ... Problem of immortal time bias in cohort studies: example using statins for preventing progression of diabetes (Source: BMJ Online First)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Get the very latest Swine Flu news via the MedWorm <b><a href="http://www.medworm.com/rss/search.php?qu=%2Bswine+%2B%28influenza+flu%29&t=Swine+Flu&f=infectiousdiseases&r=Any&o=d" target ="_self">Swine Flu RSS news feed</a></b> - updated hourly from thousands of authoritative health and news sources.</p></div> Acute exacerbation impairs endothelial function in patients with chronic obstructive pulmonary disease. CONCLUSION: Acute COPD exacerbation is associated with worsening endothelial function, increasing the risk for cardiovascular morbidity.
PMID: 20215835 [PubMed - as supplied by publisher] (Source: Turk Kardiyoloji Dernegi arsivi) Survey: Employers Plan To Shift More Health Costs To Workers News outlets report on new trends in health insurance for employers. The Washington Post: "Most big employers plan to shift a larger share of health-care costs to their workers next year, according to a survey to be released Thursday. ... (Source: Diabetes News From Medical News Today) Growth Of Chronic Kidney Disease Highlights Need For Early Detection, Greater Knowledge Of Treatment Options As the incidence of diabetes and hypertension continues to grow worldwide - and increasing numbers of patients progressing to kidney disease and kidney failure place a financial strain on public health systems - the need for early patient education about kidney disease and treatment options, including home-based treatments, has become critical... (Source: Hypertension News From Medical News Today) Growth Of Chronic Kidney Disease Highlights Need For Early Detection, Greater Knowledge Of Treatment Options As the incidence of diabetes and hypertension continues to grow worldwide - and increasing numbers of patients progressing to kidney disease and kidney failure place a financial strain on public health systems - the need for early patient education about kidney disease and treatment options, including home-based treatments, has become critical. More than 240 million people have diabetes and this figure is projected to rise to 380 million by 20251. In the United States alone, 17.9 million have been diagnosed with diabetes resulting in medical and indirect costs (e.g... (Source: Health News from Medical News Today) Access Pharmaceuticals Reports Significant Oral Bioavailability Of Cobalamin(TM) Oral Insulin In Additional Studies ACCESS PHARMACEUTICALS, INC. (OTC Bulletin Board: ACCP) announced that it has received reports of significant bioavailability of orally delivered insulin in two independently-conducted animal studies. The studies, which confirm earlier findings, were performed as part of on-going work with commercial collaborators that are evaluating Access' Cobalamin? Oral Drug Delivery Technology... (Source: Health News from Medical News Today)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Get the very latest Swine Flu news via the MedWorm <b><a href="http://www.medworm.com/rss/search.php?qu=%2Bswine+%2B%28influenza+flu%29&t=Swine+Flu&f=infectiousdiseases&r=Any&o=d" target ="_self">Swine Flu RSS news feed</a></b> - updated hourly from thousands of authoritative health and news sources.</p></div> New Alterations Found In Young Adults With Type 2 Diabetes Diet and aerobic exercise are highly effective for the treatment of type 2 diabetes, but not for obese subjects that have developed the disease when very young. A study at the Institute for Research in Biomedicine (IRB Barcelona) and Trinity College in Dublin demonstrates that obese subjects between 18 and 25 years of age carry mitochondrial proteins and genes that work abnormally and that these anomalies contribute to generating insulin resistance and a reduced response to physical exercise... (Source: Health News from Medical News Today) Access Pharmaceuticals Reports Significant Oral Bioavailability Of Cobalamin(TM) Oral Insulin In Additional Studies ACCESS PHARMACEUTICALS, INC. (OTC Bulletin Board: ACCP) announced that it has received reports of significant bioavailability of orally delivered insulin in two independently-conducted animal studies. The studies, which confirm earlier findings, were performed as part of on-going work with commercial collaborators that are evaluating Access' Cobalamin? Oral Drug Delivery Technology... (Source: Diabetes News From Medical News Today) New Alterations Found In Young Adults With Type 2 Diabetes Diet and aerobic exercise are highly effective for the treatment of type 2 diabetes, but not for obese subjects that have developed the disease when very young... (Source: Diabetes News From Medical News Today) Africa: Non Communicable Diseases Recognised As Major Cause of Premature Deaths in Developing Countries Non-communicable diseases (NCDs), such as heart diseases, diabetes, cancer and respiratory diseases account for approximately 60 percent of deaths worldwide. (Source: AllAfrica News: Health and Medicine) Knee Replacement In Elderly Patients Shown To Improve Balance Total knee replacement (TKR) successfully relieves pain and improves function in patients with advanced knee arthritis, according to a study presented today at the 2010 Annual Meeting of the American Academy of Orthopaedic Surgeons (AAOS). The surgery also significantly improves dynamic balance among elderly patients. Impaired balance and increased tendency to fall are common complaints among the elderly suffering from severe osteoarthritis (worn cartilage)... (Source: Health News from Medical News Today)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Get the very latest Swine Flu news via the MedWorm <b><a href="http://www.medworm.com/rss/search.php?qu=%2Bswine+%2B%28influenza+flu%29&t=Swine+Flu&f=infectiousdiseases&r=Any&o=d" target ="_self">Swine Flu RSS news feed</a></b> - updated hourly from thousands of authoritative health and news sources.</p></div> Knee Replacement In Elderly Patients Shown To Improve Balance Total knee replacement (TKR) successfully relieves pain and improves function in patients with advanced knee arthritis, according to a study presented today at the 2010 Annual Meeting of the American Academy of Orthopaedic Surgeons (AAOS). The surgery also significantly improves dynamic balance among elderly patients... (Source: Seniors / Aging News From Medical News Today) Australian Health Insurer NIB and Navigenics Team Up to Offer Cut-Rate Genetic Testing to NIB Customers Australian patients are using an American clinical pathology laboratory for their genetic testing needs
It?s a half-price sale of genetic clinical laboratory tests for 5,000 customers of Australian health insurer NIB. NIB wants to encourage its beneficiaries to screen themselves to identify their genetic tendencies for such conditions as heart disease, diabetes, some cancers, and [...] (Source: Dark Daily) Epidemic of Vitamin D deficiency sweeping the world (NaturalNews) There is an epidemic of vitamin D deficiency sweeping across our modern world, and it's an epidemic of such depth and seriousness that it makes the H1N1 swine flu epidemic look like a case of the sniffles by comparison. Vitamin D deficiency is not only alarmingly widespread, it's also a root cause of many other serious diseases such as cancer, diabetes, osteoporosis and heart disease.A new study published in the March, 2010 issue of the Journal of Clinical Endocrinology and Metabolism found that a jaw-dropping 59 percent of the population is vitamin D deficient. In addition, nearly 25 percent of the study subjects were found to have extremely low levels of vitamin D.Lead author of the study, Dr. Richard Kremer at the McGill University Health Center, said "Abnormal levels of v... Vitamin D Improves Insulin Sensitivity, Helps Prevent Diabetes (NaturalNews) High-dose vitamin D supplements may help increase the body's sensitivity to the blood sugar-regulating hormone insulin, thus reducing the risk of diabetes, researchers have found.Insulin resistance (or insensitivity) occurs when the body's tissues stop responding as strongly to the presence of insulin. As a consequence, the cells uptake less sugar from the bloodstream, producing the elevated glucose levels characteristic of diabetes. In the current study, conducted by researchers from Massey University and published in the British Journal of Nutrition, researchers randomly assigned 81 South Asian women between the ages of 23 and 68 to take either a placebo or 4,000 IU of vitamin D once per day. All participants suffered from insulin sensitivity at the start of the study, but ... Cholesterol Title: CholesterolCategory: Diseases and ConditionsCreated: 12/31/1997Last Editorial Review: 3/12/2010 (Source: MedicineNet Diabetes General)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Get the very latest Swine Flu news via the MedWorm <b><a href="http://www.medworm.com/rss/search.php?qu=%2Bswine+%2B%28influenza+flu%29&t=Swine+Flu&f=infectiousdiseases&r=Any&o=d" target ="_self">Swine Flu RSS news feed</a></b> - updated hourly from thousands of authoritative health and news sources.</p></div> Body's Response to Foods' Smell, Taste Could Be Diabetes Risk Factor Title: Body's Response to Foods' Smell, Taste Could Be Diabetes Risk FactorCategory: Health NewsCreated: 3/11/2010 2:10:00 PMLast Editorial Review: 3/12/2010 (Source: MedicineNet Diabetes General) Medicine's Future Could Lie in Each Patient's Genome Title: Medicine's Future Could Lie in Each Patient's GenomeCategory: Health NewsCreated: 3/11/2010 4:10:00 PMLast Editorial Review: 3/12/2010 (Source: MedicineNet Diabetes General) Body's Response to Foods' Smell, Taste Could Be Diabetes Risk Factor Title: Body's Response to Foods' Smell, Taste Could Be Diabetes Risk FactorCategory: Health NewsCreated: 3/11/2010 2:10:00 PMLast Editorial Review: 3/12/2010 (Source: MedicineNet Senior Health General) Endothelial function and oxidative stress in diabetes: active profile of the long-acting nitrate pentaerythritol tetranitrate (PETN) Abstract Diabetes is an independent risk factor for coronary artery disease. For the occurrence of cardiovascular complications in
diabetes, endothelial dysfunction plays an important role. Alterations of the endothelial-dependent coronary blood flow reserve
have been shown to be based on the reduced bioavailability of nitric oxide (NO). Therefore, pharmacological approaches, which
potentially reduce oxidative stress at the site of the endothelium, may be beneficial. As compared with other nitrates, the
long-acting nitrate pentaerythritol tetranitrate (PETN) displays characteristics which may be beneficial for the treatment
of endothelial dysfunction: apart from its vasodilatory and anti-ischemic properties, it has been shown to reduce endothelial
dysfunction by activating... Progression of diabetic retinopathy during pregnancy in women with type 2 diabetes Conclusions/interpretation Despite a low risk of progression of retinopathy in pregnant women with type 2 diabetes, sight-threatening deterioration did
occur.
Content Type Journal ArticleCategory ArticleDOI 10.1007/s00125-010-1697-9Authors
K. L. Rasmussen, Copenhagen University Hospital Department of Endocrinology, Rigshospitalet Blegdamsvej 9 2100 København Ø DenmarkC. S. Laugesen, Copenhagen University Hospital Department of Ophthalmology, Rigshospitalet Copenhagen DenmarkL. Ringholm, Copenhagen University Hospital Department of Endocrinology, Rigshospitalet Blegdamsvej 9 2100 København Ø DenmarkM. Vestgaard, Copenhagen University Hospital Department of Endocrinology, Rigshospitalet Blegdamsvej 9 2100 København Ø DenmarkP. Damm, Copenhagen University Hospital...<div id="medworm"><p><b><i>MedWorm Message:</i></b> Get the very latest Swine Flu news via the MedWorm <b><a href="http://www.medworm.com/rss/search.php?qu=%2Bswine+%2B%28influenza+flu%29&t=Swine+Flu&f=infectiousdiseases&r=Any&o=d" target ="_self">Swine Flu RSS news feed</a></b> - updated hourly from thousands of authoritative health and news sources.</p></div> Regulation of insulin secretion: role of mitochondrial signalling Abstract Pancreatic beta cells are specialised endocrine cells that continuously sense the levels of blood sugar and other fuels and,
in response, secrete insulin to maintain normal fuel homeostasis. During postprandial periods an elevated level of plasma
glucose rapidly stimulates insulin secretion to decrease hepatic glucose output and promote glucose uptake into other tissues,
principally muscle and adipose tissues. Beta cell mitochondria play a key role in this process, not only by providing energy
in the form of ATP to support insulin secretion, but also by synthesising metabolites (anaplerosis) that can act, both intra-
and extramitochondrially, as factors that couple glucose sensing to insulin granule exocytosis. ATP on its own, and possibly
modulated by these coupl... Impact of Diabetes Mellitus on the Prognosis of Patients with Oral Squamous Cell Carcinoma: A Retrospective Cohort Study Conclusion DM status could be a prognostic factor for OSCC, particularly for its effect in the survival and perineural invasion. Although
diabetes-associated comorbidities may impair decision making toward less aggressive therapeutic modality, adjuvant treatment
may be essential for DM patients to improve their survival.
Content Type Journal ArticleCategory Head and Neck OncologyDOI 10.1245/s10434-010-0996-1Authors
Cheng-Hsien Wu, Taipei Veterans General Hospital Oral and Maxillofacial Surgery, Department of Stomatology Taipei Taiwan, ROCTzu-Ying Wu, Taipei Veterans General Hospital Division of Orthodontics, Department of Stomatology Taipei Taiwan, ROCChia-Chen Li, Taipei Veterans General Hospital Division of Orthodontics, Department of Stomatology Taipei Taiwan, RO... Exercising just got easier for busy people, study shows (McMaster University) Researchers have found that interval training does not have to be "all out" to be effective in helping reduce the risk of such diseases at Type 2 diabetes. (Source: EurekAlert! - Social and Behavioral Science) Election social care truce urged MPs urge political parties to set aside "pre-election point scoring" and try to reach consensus over elderly social care in England. (Source: BBC News | Health | UK Edition) Asymmetric Large-for-Gestational-Age Infants of Type 1 Diabetic Women: Morbidity and Abdominal Growth Amer J PerinatolDOI: 10.1055/s-0030-1249362ABSTRACTWe sought to examine neonatal morbidity in four groups of offspring (asymmetric large for gestational age [LGA], symmetric LGA, asymmetric non-LGA, symmetric non-LGA) exposed in utero to maternal type 1 diabetes, and the association between rate of fetal abdominal circumference growth and asymmetric LGA. We performed a secondary analysis of 302 singleton pregnancies. Neonatal morbidity (respiratory distress syndrome, polycythemia, hypoglycemia, hyperbilirubinemia, acidosis, and composite morbidity [any of the five]) was assessed. Serial ultrasound examinations after 20 weeks' gestation were available for 35 fetuses. Logistic regression and general linear mixed modeling were used for analysis. Asymmetric LGA infants had 3.5-, 2.2-, and 3.2-...<div id="medworm"><p><b><i>MedWorm Message:</i></b> Get the very latest Swine Flu news via the MedWorm <b><a href="http://www.medworm.com/rss/search.php?qu=%2Bswine+%2B%28influenza+flu%29&t=Swine+Flu&f=infectiousdiseases&r=Any&o=d" target ="_self">Swine Flu RSS news feed</a></b> - updated hourly from thousands of authoritative health and news sources.</p></div> Diabetes Link to Eating Disorders Diabetics, under the gun to better manage their disease by controlling their food intake and weight, may find themselves in the sticky wicket of needing treatment that makes them hungry, researchers said. (Source: Disabled World) Glycemic index diet: A helpful tool for diabetes? Some people with diabetes use the glycemic index (GI) as a guide in selecting foods. (Source: MayoClinic.com - Ask a Specialist) Diabetes and Cognitive Decline: Investigating the Potential Influence of Factors Related to Health Disparities Discussion: Findings suggest that factors related to health disparities may influence cognitive outcomes among older adults with diabetes. (Source: Journal of Aging and Health) Factors Influencing Driving Status in an Older Latino Population This study uses cross-sectional data from 421 elderly Latino participants in the Los Angeles Latino Eye Study (LALES) along with cognitive screening, and comparison is by driving status (currently driving, used to drive, never drove) and self-reported difficulty driving among current drivers. Results: Current drivers were more educated and reported better health.Those who never drove were less acculturated.Those who gave up driving had more visual impairment and lower scores on mental status testing. Self-reported difficulties among current drivers were associated with more health problems but not cognitive difficulties. Discussion: Elderly Latinos have a lower driving rate than the general older population. There are significant differences between older Latinos who continue to drive vers... Prevalence and Correlates of Functional Status in an Older Community-- Representative Sample in Brazil Discussion: A large proportion of noninstitutionalized elderly have ADL problems. In addition to health care, interventions promoting equity of access to education and economic opportunity could reduce ADL dependency in coming generations. (Source: Journal of Aging and Health)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Get the very latest Swine Flu news via the MedWorm <b><a href="http://www.medworm.com/rss/search.php?qu=%2Bswine+%2B%28influenza+flu%29&t=Swine+Flu&f=infectiousdiseases&r=Any&o=d" target ="_self">Swine Flu RSS news feed</a></b> - updated hourly from thousands of authoritative health and news sources.</p></div> Do elderly edentulous patients with a history of periodontitis harbor periodontal pathogens? The presence of periodontal pathogens in the oral cavity may impact implant survival. Therefore, this study aimed to determine the prevalence of Campylobacter rectus, Porphyromonas gingivalis, Aggregatibacter actinomycetemcomitans, Prevotella intermedia, Tannerella forsythia, Treponema denticola, Eikenella corrodens and Parvimonas micra in a specific elderly population with a history of periodontitis who have never worn dentures. Thirty dentate subjects (mean age 61.7±7.05 years) and 30 edentulous subjects (mean age 65.8±8.05 years) were included in this cross-sectional study. Microbiological samples of cheek mucosa and the dorsum of the tongue were taken from all subjects. In addition, sulcus samples were taken from the dentate group. All samples were analysed using a bacterial DNA-spec... [Viewpoint] The role of academic health science systems in the transformation of medicine The challenges facing the health of communities around the world are unprecedented, and the data are all too familiar. For 5 billion people living in developing countries, environmental factors and inadequacies in hygiene, economic development, and health-care access are the main causes of shortened life expectancies. Improvements in health status, including reductions in infant mortality and declining incidence of infectious diseases, are being met by the new epidemics of obesity, diabetes mellitus, and cardiovascular disease. (Source: LANCET) Dietary fat and bile juice, but not obesity, are responsible for the increase in small intestinal permeability induced through the suppression of tight junction protein expression in LETO and OLETF rats. Conclusion:
Excessive dietary fat and/or increased levels of luminal bile juice, but not genetic obesity, are responsible for the increase in small intestinal permeability resulting from the suppression of TJ protein expression. (Source: Nutrition & Metabolism) Further evidence that mutations in INS can be a rare cause of Maturity-Onset Diabetes of the Young (MODY) Conclusion:
Mutations in INS can be a rare cause of MODY and we conclude that screening for mutations in INS should be recommended in MODYX patients. (Source: BMC Medical Genetics - Latest articles) Slower Visuomotor Corrections with Unchanged Latency are Consistent with Optimal Adaptation to Increased Endogenous Noise in the Elderly Author Summary
In a hand-eye coordination task that requires continuous movement to correct for a disturbance, it turns out that signs of response to the disturbance appear no later in the elderly than in the young. The elderly motion is noisy and less efficient, however, and once movements in response to a disturbance begin, they are at a lower speed. One can model subject response by assuming that it results from combining noise and a response that is mathematically optimal given this noise, delay, and a least-squares sort of control objective. This modeling approach is appropriate for young and most elderly subjects. The model holds that increased noise should lead to no change in delay until response gets underway, but should make the response itself proceed at a slower speed. This is...<div id="medworm"><p><b><i>MedWorm Message:</i></b> Get the very latest Swine Flu news via the MedWorm <b><a href="http://www.medworm.com/rss/search.php?qu=%2Bswine+%2B%28influenza+flu%29&t=Swine+Flu&f=infectiousdiseases&r=Any&o=d" target ="_self">Swine Flu RSS news feed</a></b> - updated hourly from thousands of authoritative health and news sources.</p></div> Clinical Trial Summary: Assessment on the Prevention of Progression by Rosiglitazone on Atherosclerosis in Diabetes Patients With Cardiovascular History (APPROACH) The goal of the trial was to evaluate treatment with rosiglitazone compared with glipizide among patients with type 2 diabetes. (Source: Cardiosource) Age influences glucose handling in acute phase of STEMI Older patients have higher glucose levels and worse glycemic control in the early phase of ST-elevation myocardial infarction than younger patients, although insulin resistance does not vary by age, Italian researchers have shown. (Source: MedWire News - Diabetes) Metformin and reduced risk of hepatocellular carcinoma in diabetic patients with chronic liver disease Previous studies have reported the association between type 2 diabetes mellitus (DM2) and hepatocellular carcinoma (HCC). To explore the relationships among DM2, antidiabetic therapy and HCC risk. We recruited 610 HCC patients compared with 618 matched cirrhotic patients and 1696 Controls. The odds ratio (OR) for HCC in diabetic subjects treated with insulin, sulphonylureas and metformin was calculated. DM2 prevalence was 31.2% in HCC, 23.3% in cirrhotic patients and 12.7% in Controls (P (Source: Liver International) Research protocol of the NeedYD-study (Needs in Young onset Dementia): a prospective cohort study on the needs and course of early onset dementia DiscussionThe study protocol of the NeedYD-study is presented here. To our knowledge, this study is the first prospective cohort study in this research area. Although some limitations exist, these do not outweigh the strong points of this study design. (Source: BMC Geriatrics) Diabetic Nephropathy Classification Developed A new consensus on the classification of type 1 and type 2 diabetes-related nephropathy, dividing
diabetic nephropathy into four hierarchical glomerular lesions with varying degrees of severity, may aid
international clinical practice, according to an article published online Feb. 18 in the Journal of the American
Society of Nephrology. (Source: Modern Medicine)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Get the very latest Swine Flu news via the MedWorm <b><a href="http://www.medworm.com/rss/search.php?qu=%2Bswine+%2B%28influenza+flu%29&t=Swine+Flu&f=infectiousdiseases&r=Any&o=d" target ="_self">Swine Flu RSS news feed</a></b> - updated hourly from thousands of authoritative health and news sources.</p></div> Leptin Shows Advantages Over Insulin in Type 1 Diabetes The ability of leptin to restore hemoglobin A1c to normal in mice with diabetes (along with its
additional benefits relating to body fat and cholesterol) suggests that the hormone may have a role in treating
type 1 diabetes mellitus in humans, and may have both short- and long-term advantages over insulin monotherapy,
according to research published online March 1 in the Proceedings of the National Academy of
Sciences. (Source: Modern Medicine) Teaching energy metabolism using scientific articles This work describes the use of a virtual learning environment (VLE) applied to the biochemistry class for undergraduate, first-year medical students at the Federal University of Rio de Janeiro. The course focused on the integration of energy metabolism, exploring metabolic adaptations in different physiological or pathological states such as starvation, diabetes, and exercise. The VLE was designed to combine online activities with traditional course content and presented guided inquiry-based activities to assist in the use of original scientific articles as educational resources. Based on the analysis of a semi-open questionnaire, the results provided evidence that the VLE encouraged students' engagement in activities and improved feedback. The results also suggested that guided inquiry-ba... Oxidative and Nitrosative Stress and Progression of Diabetic Nephropathy in Type 2 Diabetes Am J Nephrol 2010;31:342–352 (DOI:10.1159/000297290) (Source: Karger Publishers) McCormick Recall Due to Possible Health Risk from HVP Ingredient Expands to Include Additional "Best By" Dates McCormick & Company, Incorporated (NYSE:MKC) is expanding a March 5, 2010 recall to include additional "Best By" dates of products manufactured with HVP (hydrolyzed vegetable protein) supplied by Basic Food Flavors of Las Vegas, Nevada, because the ingredient has the potential to be contaminated with Salmonella. "Consumption of products containing Salmonella can cause serious and sometimes fatal infections in young children, frail or elderly people, and others with weakened immune systems... (Source: Food and Drug Administration) Big first trimester weight gain ups diabetes risk NEW YORK (Reuters Health) - Women who gain weight too quickly during the first three months of pregnancy are more prone to develop pregnancy-related diabetes, new research shows. (Source: Reuters: Health)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Get the very latest Swine Flu news via the MedWorm <b><a href="http://www.medworm.com/rss/search.php?qu=%2Bswine+%2B%28influenza+flu%29&t=Swine+Flu&f=infectiousdiseases&r=Any&o=d" target ="_self">Swine Flu RSS news feed</a></b> - updated hourly from thousands of authoritative health and news sources.</p></div> Big First Trimester Weight Gain Ups Diabetes Risk Women who gain weight too quickly during the first three months of pregnancy are more prone to develop pregnancy-related diabetes, new research shows.Source: Reuters Health
Related MedlinePlus Page: Diabetes and Pregnancy (Source: MedlinePlus Health News) Comorbid Diabetes and Depression Increase Dementia Risk Patients with diabetes and major depression have a markedly increased risk of developing dementia compared with their counterparts with diabetes alone. Medscape Medical News (Source: Medscape Today Headlines) FDA Says No "Clear Connection" Between Bisphosphonate Use and Femur Fracture Risk FDA Says No "Clear Connection" Between Bisphosphonates, Femur Fracture Risk Medscape Medical News (Source: Medscape Today Headlines) Austinuts Of Dallas, Inc. Announces Voluntary Recall of Honey Mustard Pretzels Austinuts of Dallas, Inc. has issued a voluntary recall for Honey Mustard Pretzels, Lot number 61150/0280 because the product may be contaminated with Salmonella. Salmonella is an organism which can cause serious and sometimes fatal infections in young children, frail or elderly people, and others with weakened immune systems. (Source: Food and Drug Administration) Body's Response to Foods' Smell, Taste Could Be Diabetes Risk Factor A gene mutation could trigger key insulin reaction in some, researchers say
Source: HealthDay
Related MedlinePlus Pages: Diabetes, Genes and Gene Therapy, Taste and Smell Disorders (Source: MedlinePlus Health News)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Get the very latest Swine Flu news via the MedWorm <b><a href="http://www.medworm.com/rss/search.php?qu=%2Bswine+%2B%28influenza+flu%29&t=Swine+Flu&f=infectiousdiseases&r=Any&o=d" target ="_self">Swine Flu RSS news feed</a></b> - updated hourly from thousands of authoritative health and news sources.</p></div> Metabolic disease prevention and suppression of fat accumulation by Salacia reticulata In this study, we attempted to
clarify the antiobesity mechanism and the safety of S. reticulata in vivo and in vitro. We gave ordinary MF feed, alone or mixed with S. reticulata (0.3 or 1.0%), to Tsumura Suzuki obesity diabetes (TSOD) mice (spontaneous obese type II diabetes model mice) and Tsumura
Suzuki non-obese (TSNO) mice (the corresponding reference animals), ad libitum for 2 months. As compared with the TSNO control
mice, the TSOD control mice became obese due to fat accumulation and developed various signs of metabolic diseases. The TSOD
mouse group receiving S. reticulata showed the following effects: suppression of body weight increase and fat accumulation, alleviation of abnormal lipid metabolism
and abnormal glucose tolerance, and suppression of intrahepatic fat accu... Diagnostic and prognostic testing to evaluate coronary artery disease in patients with diabetes mellitus Abstract Coronary artery disease (CAD) continues to be the most common cause of morbidity and mortality in patients with diabetes mellitus
(DM). In recent years, the strategies for treatment of CAD in DM have undergone much evolution. Currently, all patients with
DM, regardless of symptoms or diagnosed CAD, are treated aggressively for CAD risk factor reduction. In this clinical climate,
the ability to specifically identify patients with disease that will benefit from more aggressive and invasive therapies remains
a challenge. In this article we review the current literature on diagnostic and prognostic utility of conventional non-invasive
modalities for assessment of CAD in patients with DM, as well as on novel and emerging methods for CAD risk stratification.
Content... Knee Replacement in Seniors Improves Balance Knee replacement in elderly patients shown to improve balance - Multiple benefits to surgery reported for patients with advanced osteoarthritis. (Source: Disabled World) Pregnancy characteristics and maternal breast cancer risk: a review of the epidemiologic literature Abstract The short- and long-term effects of pregnancy on breast cancer risk are well documented. Insight into potential biological
mechanisms for these associations may be gained by studying breast cancer risk and pregnancy characteristics (e.g., preeclampsia,
twining), which may reflect hormone levels during pregnancy. To date, no review has synthesized the published literature for
pregnancy characteristics and maternal breast cancer using systematic search methods. We conducted a systematic search to
identify all published studies. Using PUBMED (to 31 July 2009), 42 relevant articles were identified. Several studies suggest
that multiple births may be associated with a lowered breast cancer risk of about 10?30%, but results were inconsistent across
18 studies. The maj... Utilities and disutilities for attributes of injectable treatments for type 2 diabetes Discussion The three injection attributes were associated with small utility shifts in the expected directions. Dose frequency appears
to be the most important of the three attributes from the patients? perspective. The vignette-based SG approach was feasible
and useful for assessing added utility or disutility of injection-related attributes associated with treatments for type 2
diabetes.
Content Type Journal ArticleCategory Original PaperDOI 10.1007/s10198-010-0224-8Authors
Kristina S. Boye, Eli Lilly and Company Indianapolis IN USALouis S. Matza, United BioSource Corporation Center for Health Outcomes Research 7101 Wisconsin Avenue, Suite 600 Bethesda MD 20814 USAKimberly N. Walter, United BioSource Corporation Center for Health Outcomes Research 7101 Wisconsi...<div id="medworm"><p><b><i>MedWorm Message:</i></b> Get the very latest Swine Flu news via the MedWorm <b><a href="http://www.medworm.com/rss/search.php?qu=%2Bswine+%2B%28influenza+flu%29&t=Swine+Flu&f=infectiousdiseases&r=Any&o=d" target ="_self">Swine Flu RSS news feed</a></b> - updated hourly from thousands of authoritative health and news sources.</p></div> Enhanced expression of naofen in kidney of streptozotocin-induced diabetic rats: possible correlation to apoptosis of tubular epithelial cells Conclusions These data suggest that naofen expression may be upregulated by hyperglycemia, with possible correlation to apoptosis of tubular
epithelial cells and thereby to diabetic nephropathy.
Content Type Journal ArticleCategory Original ArticleDOI 10.1007/s10157-010-0276-1Authors
Yuko Sato, Aichi Medical University School of Medicine Department of Anesthesiology Nagakute Aichi-gun Aichi 480-1195 JapanGuo-Gang Feng, Aichi Medical University School of Medicine Department of Pharmacology Nagakute Aichi-gun Aichi 480-1195 JapanLei Huang, Aichi Medical University School of Medicine Department of Pharmacology Nagakute Aichi-gun Aichi 480-1195 JapanJun-Hua Fan, Nagoya University Graduate School of Medicine Department of Gastroenterology 65 Tsuruma-cho, Showa-ku Nagoya A... Cholesterol, Diabetes Medications Top List of Prescription Drug Expenses for Medicare Recipients Metabolic agents make up nearly one quarter of all purchases by those aged 65 years and older. Medscape Medical News (Source: Medscape Today Headlines) Hybrid Thoracoabdominal Aortic Aneurysm Repair: Concomitant Visceral Revascularization and Endovascular Aneurysm Exclusion Thoracoabdominal aortic aneurysms (TAAA) remain a formidable surgical challenge, with conventional open repair associated with significant rates of mortality and morbidity. Furthermore, many of these patients are elderly with significant comorbidities and may not be candidates for repair. Consequently, the availability of a ?hybrid? option, including open visceral debranching with concomitant endovascular aneurysm exclusion, may have advantages in these high-risk patients, including the potential to offer therapy to those ineligible for conventional repair. Our technique for hybrid TAAA repair is performed by means of midline laparotomy. A commercially manufactured custom multibranched Dacron graft is used to sequentially bypass, in extranatomic manner, the left renal artery, superior ... Long-Acting Insulin Analogs May up Risk of Diabetic Ketoacidosis in Children Use of insulin glargine or detemir rather than NPH insulin does not reduce the risk of ketoacidosis in children and adolescents with type 1 diabetes, and in fact may increase the risk, a new study shows. Reuters Health Information (Source: Medscape Diabetes Headlines) Overview on practices in thalassemia intermedia management aiming for lowering complication rates across a region of endemicity: the OPTIMAL CARE study This study provides evidence that calls for prospective evaluation of the roles of transfusion, iron chelation, and hydroxyurea therapy in TI patients. (Source: Blood)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Get the very latest Swine Flu news via the MedWorm <b><a href="http://www.medworm.com/rss/search.php?qu=%2Bswine+%2B%28influenza+flu%29&t=Swine+Flu&f=infectiousdiseases&r=Any&o=d" target ="_self">Swine Flu RSS news feed</a></b> - updated hourly from thousands of authoritative health and news sources.</p></div> Adherence Studies in Adolescents with Chronic Kidney or Urologic Diseases, or Diabetes (R01) Funding Opportunity Number: RFA-DK-10-004 Opportunity Category: DiscretionaryFunding Instrument Type: GrantCategory of Funding Activity: Food and NutritionHealthCFDA Number: 93.847Eligible Applicants State governmentsCounty governmentsCity or township governmentsSpecial district governmentsIndependent school districtsPublic and State controlled institutions of higher educationNative American tribal governments (Federally recognized)Public housing authorities/Indian housing authoritiesNative American tribal organizations (other than Federally recognized tribal governments)Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher educationNonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher educationPrivate instit... World Kidney Day Podcast The focus on diabetic kidney disease for World Kidney Day 2010 brings awareness of the magnitude of the problem and ramifications for global health for people with diabetes and kidney disease. It is therefore time to act and act urgently. It is time for strategies that prevent diabetes and its sequelae. It is time for programs for health care workers to diagnose and treat people with diabetic kidney disease. It is time for governments to pass legislation to enable the diabetes pandemic to be controlled. After all, diabetic kidney disease, like the epidemics of infectious diseases that have long dominated public health agendas, is potentially preventable. Indeed, March 11, 2010 is time to act on diabetic kidney disease and to commit to sustaining that action long after World Kidney Day.
Li... 2009 H1N1 Influenza and its Impact on People with Chronic Medical Conditions: Questions and Answers The January 12, 2010 National Influenza Vaccination Week Webinar featured Dr. Nicole Lurie with the US Department of Health and Human Services; Dr. Anthony Fiore with Centers for Disease Control and Prevention; Dr. Otis Webb Brawley with American Cancer Society; Christine Tobin with American Diabetes Association; and Mary Partridge with the American Lung Association. (Source: PandemicFlu.gov RSS Feed for News Releases) Metabolic Meds Top Medicare Drug Spending Metabolic drugs (MedPage Today) -- namely cholesterol and diabetes meds -- account for the greatest Medicare prescription expenses, researchers say. (Source: MedPage Today Public Health) Protect Your Kidneys by Controlling Diabetes and High Blood Pressure Source: Centers for Disease Control and Prevention
Related MedlinePlus Pages: Diabetic Kidney Problems, Kidney Diseases (Source: MedlinePlus Health News)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Get the very latest Swine Flu news via the MedWorm <b><a href="http://www.medworm.com/rss/search.php?qu=%2Bswine+%2B%28influenza+flu%29&t=Swine+Flu&f=infectiousdiseases&r=Any&o=d" target ="_self">Swine Flu RSS news feed</a></b> - updated hourly from thousands of authoritative health and news sources.</p></div> Foods high in meat and fat confer increased risk for diabetes in all ethnic groups Foods high in meat and fat appear to confer an increased risk for diabetes in all ethnic groups, whereas the effects of other dietary patterns vary by gender and ethnicity, say US researchers. (Source: MedWire News - Diabetes) New Knee May Improve Balance Replacement joint seems to help prevent falls among elderly, study finds
Source: HealthDay
Related MedlinePlus Pages: Falls, Knee Replacement (Source: MedlinePlus Health News) Impact of Chronic Kidney Disease on Platelet Function Profiles in Diabetes Mellitus Patients With Coronary Artery Disease Taking Dual Antiplatelet Therapy Conclusions: In DM patients with coronary artery disease taking maintenance aspirin and clopidogrel therapy, impaired renal function is associated with reduced clopidogrel-induced antiplatelet effects and a greater prevalence of HPPR. (Source: Journal of the American College of Cardiology) Determinants of Coronary Calcium Conversion Among Patients With a Normal Coronary Calcium Scan: What Is the ?Warranty Period? for Remaining Normal? Conclusions: Among individuals with CAC = 0, conversion to CAC >0 is nonlinear and occurs at low frequency before 4 years. No clinical factor seems to mandate earlier repeat CAC scanning. (Source: Journal of the American College of Cardiology) Single and unhappily married men are at 64% higher risk of dying from stroke Men who were single in the 1960s were 64% more likely to suffer a fatal stroke over the next three decades than their married counterparts.The risk of fatal stroke was also 64% higher in men who reported dissatisfaction with their marriages than in men who rated their marriages as successful.That figure is comparable to the risk of fatal stroke faced by men with diabetes.References:Single Men Have Higher Risk of Stroke. WebMD.Image source: CT scan slice of the brain showing a right-hemispheric ischemic stroke (left side of image). Wikipedia, GNU Free Documentation License.
Posted at Clinical Cases and Images. Stay updated and subscribe, follow on Twitter and Buzz, and connect on Facebook. (Source: Clinical Cases and Images)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Get the very latest Swine Flu news via the MedWorm <b><a href="http://www.medworm.com/rss/search.php?qu=%2Bswine+%2B%28influenza+flu%29&t=Swine+Flu&f=infectiousdiseases&r=Any&o=d" target ="_self">Swine Flu RSS news feed</a></b> - updated hourly from thousands of authoritative health and news sources.</p></div> Medical care costs among patients with established cardiovascular disease. CONCLUSIONS: The economic burden of providing care to patients with CVD may be substantially greater than current American Heart Association estimates. Although several comorbid conditions undoubtedly contribute to these costs, avoidance of secondary CVD hospitalization may be the key to substantially reducing healthcare consumption.
PMID: 20205493 [PubMed - in process] (Source: The American Journal of Managed Care) New cholesterol drug tested Conclusion
This is an important and well-conducted trial, which has demonstrated the potential of a drug, eprotirome, to lower cholesterol levels. However, conclusions about the effects of this drug should not be made too prematurely and much further research is needed:
So far, use of the drug alone has not been compared to statin treatment. In this trial eprotirome or inactive placebo was only ever given in addition to people?s long-term statins. Therefore no comparison of cholesterol-lowering effect of each of the treatments alone can be made.
Only a small number of people were included in the trial: 47 on the 25microgram dose, 46 on 50micrograms, and 44 on the 100microgram dose of eprotirome. These groups of participants are too small to draw any conclusions on the safety or eff... Agency For Healthcare Research And Quality News And Numbers: High Cholesterol, Diabetes Lead Drug Spending For The Elderly Purchases of cholesterol and diabetes prescription drugs by elderly Medicare beneficiaries reached nearly $19 billion in 2007 - about one-fourth of the approximately $82 billion spent for medications for the elderly, according to the latest AHRQ News and Numbers... (Source: Cholesterol News From Medical News Today) The American Diabetes Association Encourages Community Organizations To Join The Movement To Stop Diabetes The American Diabetes Association announced today their efforts to further engage community organizations across the country in raising awareness about the seriousness of diabetes and its complications through the Association's Stop Diabetes movement. The American Diabetes Association is rolling out a Stop Diabetes Community Outreach Toolkit to help community and faith-based organizations, health clinics, libraries, hospitals, fraternal groups and corporations raise awareness of diabetes risk factors among their constituents... (Source: Health News from Medical News Today) Agency For Healthcare Research And Quality News And Numbers: High Cholesterol, Diabetes Lead Drug Spending For The Elderly Purchases of cholesterol and diabetes prescription drugs by elderly Medicare beneficiaries reached nearly $19 billion in 2007 - about one-fourth of the approximately $82 billion spent for medications for the elderly, according to the latest AHRQ News and Numbers. Metabolic drugs, which are used to lower cholesterol levels, keep diabetes under control and for weight and thyroid problems, topped the list of the five leading categories of drugs purchased by the elderly... (Source: Health News from Medical News Today)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Get the very latest Swine Flu news via the MedWorm <b><a href="http://www.medworm.com/rss/search.php?qu=%2Bswine+%2B%28influenza+flu%29&t=Swine+Flu&f=infectiousdiseases&r=Any&o=d" target ="_self">Swine Flu RSS news feed</a></b> - updated hourly from thousands of authoritative health and news sources.</p></div> Glycated Hemoglobin Tests See Increasing Use Glycated hemoglobin (HbA1c) testing is one of the success stories of point-of-care diagnostics, and an area that will experience higher growth rates than other POC tests as a result of expert recommendations, new cases and booming mail-in test sales, according to the new report "Point-of-care Diagnostics 2010 and Beyond: Rapid Testing at a Crossroads," by healthcare market research publisher Kalorama Information. The test measures glucose attached to the blood protein hemoglobin, a well-established analyte related to the long-term evaluation of blood sugar control... (Source: Health News from Medical News Today) The American Diabetes Association Encourages Community Organizations To Join The Movement To Stop Diabetes The American Diabetes Association announced today their efforts to further engage community organizations across the country in raising awareness about the seriousness of diabetes and its complications through the Association's Stop Diabetes movement... (Source: Diabetes News From Medical News Today) Glycated Hemoglobin Tests See Increasing Use Glycated hemoglobin (HbA1c) testing is one of the success stories of point-of-care diagnostics, and an area that will experience higher growth rates than other POC tests as a result of expert recommendations, new cases and booming mail-in test sales, according to the new report "Point-of-care Diagnostics 2010 and Beyond: Rapid Testing at a Crossroads," by healthcare market rese... (Source: Diabetes News From Medical News Today) Recent Studies Link Obesity To Food Allergies First Lady Michelle Obama's "Let's Move" Campaign tells us that about 32 percent of children and teens (or 25 million) are obese or overweight. It revealed those extra pounds put them at greater risk of developing debilitating and costly diseases including diabetes, high blood pressure and high cholesterol and may also cause them to lead a two to five year shorter life than their parents... (Source: Health News from Medical News Today) Recent Studies Link Obesity To Food Allergies First Lady Michelle Obama's "Let's Move" Campaign tells us that about 32 percent of children and teens (or 25 million) are obese or overweight. It revealed those extra pounds put them at greater risk of developing debilitating and costly diseases including diabetes, high blood pressure and high cholesterol and may also cause them to lead a two to five year shorter life than their parents... (Source: Allergy News From Medical News Today)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Get the very latest Swine Flu news via the MedWorm <b><a href="http://www.medworm.com/rss/search.php?qu=%2Bswine+%2B%28influenza+flu%29&t=Swine+Flu&f=infectiousdiseases&r=Any&o=d" target ="_self">Swine Flu RSS news feed</a></b> - updated hourly from thousands of authoritative health and news sources.</p></div> No mortality benefit in reducing HbA1c below 9% There is little to gain in terms of reduced mortality from continually lowering HbA1c targets in patients with type 2 diabetes, a Dutch study has concluded. (Source: Pulse) Revascularization for coronary artery disease in diabetes mellitus: Angioplasty, stents and coronary artery bypass grafting Abstract Patients with diabetes mellitus (DM) are prone to a diffuse and rapidly progressive form of atherosclerosis, which increases
their likelihood of requiring revascularization. However, the unique pathophysiology of atherosclerosis in patients with DM
modifies the response to arterial injury, with profound clinical consequences for patients undergoing percutaneous coronary
intervention (PCI). Multiple studies have shown that DM is a strong risk factor for restenosis following successful balloon
angioplasty or coronary stenting, with greater need for repeat revascularization and inferior clinical outcomes. Early data
suggest that drug eluting stents reduce restenosis rates and the need for repeat revascularization irrespective of the diabetic
state and with no signifi... Clinical outcomes in diabetic and non-diabetic patients with drug-eluting stents: results from the first phase of the prospective multicenter German DES.DE registry Conclusion Data collected in DES.DE revealed that despite the use of DES the risk of myocardial infarction, death, and thrombotic events
remains higher in diabetic patients.
Content Type Journal ArticleCategory Original PaperDOI 10.1007/s00392-010-0136-8Authors
Ibrahim Akin, University Hospital Rostock, Rostock School of Medicine Divisions of Cardiology, Pulmonology, Department of Internal Medicine I, Intensive Care Unit Ernst-Heydemann-Str. 6 18057 Rostock GermanyAlexander Bufe, University of Witten/Herdecke Department of Cardiology, Helios Clinic Wuppertal Wuppertal GermanySteffen Schneider, Heart Center Ludwigshafen Department of Cardiology Ludwigshafen GermanyHolger Reinecke, University Hospital Münster Department of Cardiology Münster GermanyLars Eckardt, Univ... Oligodeoxynucleotide IMT504 induces a marked recovery in a streptozotocin-induced model of diabetes in rats: correlation with an early increase in the expression of nestin and neurogenin 3 progenitor cell markers Conclusions/interpretation IMT504 induced a marked recovery of STZ-induced diabetes that correlated with early production of progenitor cell markers,
such as nestin and NGN3.
Content Type Journal ArticleCategory ArticleDOI 10.1007/s00125-010-1694-zAuthors
M. S. Bianchi, Institute of Biology and Experimental Medicine (IBYME-CONICET) Buenos Aires ArgentinaA. Hernando-Insúa, Immunotech Buenos Aires ArgentinaN. A. Chasseing, Institute of Biology and Experimental Medicine (IBYME-CONICET) Buenos Aires ArgentinaJ. M. Rodríguez, Fundación Pablo Cassará Buenos Aires ArgentinaF. Elías, Fundación Pablo Cassará Buenos Aires ArgentinaN. Lago, Gema Biotech Buenos Aires ArgentinaJ. Zorzopulos, Immunotech Buenos Aires ArgentinaC. Libertun, Institute of Biology and Experimenta...
food pyramid is different from the Food Guide Pyramid put out by the USDA in that it groups foods based on the levels of carbohydrates and proteins, rather than by food classification. Portion sizes also tend to be different, in order to have similar carbohydrate content for each individual serving. Examples of this are cheese, which can be found in the meat group rather than in its typical home in dairy, and potatoes can be found in the starchy foods group rather than with the rest of the vegetables. These differences have been created in order to make the carbohydrate levels approximately equal between each food group.
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