diabetes guide
 

Diabetes: Half Of People With Diabetes Don't Take Aspirin Therapy
By Hector Milla
The American College of Preventive Medicine (ACPM) found that 48 per cent of U.S. adults over forties with do not take aspirin therapy to reduce their risk of recurrent heart attack or stroke and they even do not report or discuss this situation with their doctors.
This population is at intensified risk of cardiovascular cases and hence it is potential candidate for a doctor-recommended aspirin therapy based on nowadays American Association (ADA) and U.S. Preventive Services Task Force principles.
Some of the most life-threatening consequences of diseases are heart attack and stroke, which occur more than twice as often among people with than in those who are not affected by the illness. According to statistics, this situation accounts for approximately 65 per cent of deaths in people with diabetes.
A diagnosis of as an adult presents a similar level of coronary heart disease risk as already having suffered a heart attack, under the American Association. Hence, this association recommends that aspirin therapy should be considered for use in the prevention of both first and recurrent cardiovascular events in patients affected by who have at least one additional risk factor.
According to the experts, the survey findings suggest that few Americans with are aware of aspirin therapy and its cardio-protective benefits. Despite benefits of aspirin therapy have been proven to outweigh the risks in moderate to high risk populations, it is concerning that so many people with seem unaware of this fact.

Article written by Hector Milla editor of http://www.mydiabetessupply.com, a website about testing supply, or you may read their last article :: D Chiro Inositol

Britain Must Double Spending on Elderly Care: Study
Spending on care for the elderly must more than double over the next 15 years just to keep the same level of service for a rapidly aging population, a think tank said in a report on Tuesday. Reuters Health Information (Source: Medscape Medical News Headlines)
Salsalate Shows Promise in Treating Type 2 Diabetes
Drug efficacy points to possible inflammatory pathogenesis of diabetes, researchers say. Medscape Medical News (Source: Medscape Today Headlines)
Editorial Board
(Source: Primary Care Diabetes)
Contents
(Source: Primary Care Diabetes)
American Diabetes Association: Are You Surrounded by Risk?
ALEXANDRIA, VA (MARKET WIRE) To combat the growing diabetes epidemic, the American Diabetes Association is asking Americans -- "What will you do to Stop Diabetes? Know your risk." On March 23, the 22nd annual American Diabetes Association Alert Day(SM), the Association is encouraging people to join the Stop Diabetes movement by taking the Diabetes Risk Test (at stopdiabetes.com or 800-DIABETES) to find out if they are at risk for developing type 2 diabetes and how they can take action to prevent the disease. (Source: Market Wire - Pharmaceuticals and Biotech)
Potential new drug for type 2 diabetes
An experimental oral drug has lowered blood sugar levels and inflammation in mice with Type 2 diabetes, suggesting that the medication could someday be added to the arsenal of drugs used by millions of Americans with this disease, according to new research. (Source: ScienceDaily Headlines)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Get the very latest Swine Flu news via the MedWorm <b><a href="http://www.medworm.com/rss/search.php?qu=%2Bswine+%2B%28influenza+flu%29&t=Swine+Flu&f=infectiousdiseases&r=Any&o=d" target ="_self">Swine Flu RSS news feed</a></b> - updated hourly from thousands of authoritative health and news sources.</p></div>
Soy Formula, Maternal Diabetes Linked To Daughters' Fibroids
RESEARCH TRIANGLE PARK, N.C. - Analysis of the 2010 National Institute of Environmental Health Sciences Sister Study data for predictors of early uterine fibroid diagnoses found that an increased risk is associated with being fed soy formula and prepregnancy maternal diabetes, according to research published online March 2 by Environmental Health Perspectives (118;3:375-381). Full story on lexis.com (Source: LexisNexis&#174; Mealey's&#8482; Emerging Toxic Torts Legal News)
Medtronic Receives FDA Approval for Industry's Most Advanced Integrated System for Diabetes Management
Next Generation Integrated System – MiniMed Paradigm&reg; REAL-Time Revel™ System – Incorporates Predictive Alerts to Help Patients More Tightly Control Diabetes MINNEAPOLIS--(HSMN NewsFeed)--Medtronic, Inc. (NYSE:MDT ) today announced it has received U... Devices, Endocrinology, FDAMedtronic, MiniMed Paradigm, insulin pump, glucose monitor (Source: HSMN NewsFeed)
FDA approves Medtronic diabetes system
Medtronic Inc. on Wednesday said federal regulators have approved its diabetes-management system, which includes features such as predictive alerts that warn diabetics about possible high or low blood sugar. (MDT) (Source: bizjournals.com Health Care:Biotechnology headlines)
2008 Kent award lecture: an historian interprets the future of gerontology.
Authors: Achenbaum WA Donald Peterson Kent believed that gerontology would grow through innovative inquiry, effective teaching, and well-evaluated policies and programs that benefited the elderly people. Because advances in research, education, and practice sustain each other, Kent's tripartite agenda continues to be instructive as globalization presents fresh challenges and opportunities for gerontologists to advance our multifaceted, multidisciplinary, multinational enterprise. Donald Kent's vision offers a compelling blueprint for interpreting the field's future as gerontologists engage in theory building, educational trail blazing, and redefining older people's roles in aging societies. PMID: 20231175 [PubMed - in process] (Source: The Gerontologist)
Improving end of life care for nursing home residents: an analysis of hospital mortality and readmission rates
Conclusion Survival rates in nursing home residents admitted to an acute medical unit are low, and measures are suggested to reduce inappropriate admissions and facilitate improved end of life care. (Source: Postgraduate Medical Journal)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Get the very latest Swine Flu news via the MedWorm <b><a href="http://www.medworm.com/rss/search.php?qu=%2Bswine+%2B%28influenza+flu%29&t=Swine+Flu&f=infectiousdiseases&r=Any&o=d" target ="_self">Swine Flu RSS news feed</a></b> - updated hourly from thousands of authoritative health and news sources.</p></div>
New deal would see 50% more elderly people in England helped with costs of social care
(Source: BMJ Online First)
Resveratrol - A Miracle Anti-Aging Drug Or Not?
Imagine a wonder drug that could slow down the aging process, and potentially one day provide a cure for disease such as diabetes and cancer. (Source: WBZ-TV - Breaking News, Weather and Sports for Boston, Worcester and New Hampshire)
Risk Factor Analysis In A Contemporary Cystectomy Cohort Using Standardized Reporting Methodology And Adverse Event Criteria
UroToday.com - Despite significant improvements in surgical technique, preoperative preparation and perioperative care since the inception of radical cystectomy (RC), the complication rate associated with this operation remains high. Patients requiring RC are elderly with considerable associated comorbidities due to the strong association of cigarette smoking and urothelial bladder carcinoma... (Source: Health News from Medical News Today)
Risk Factor Analysis In A Contemporary Cystectomy Cohort Using Standardized Reporting Methodology And Adverse Event Criteria
UroToday.com - Despite significant improvements in surgical technique, preoperative preparation and perioperative care since the inception of radical cystectomy (RC), the complication rate associated with this operation remains high. Patients requiring RC are elderly with considerable associated comorbidities due to the strong association of cigarette smoking and urothelial bladder carcinoma... (Source: Urology / Nephrology News From Medical News Today)
ACCORD Lipid Study Brings New Hope To People With Type 2 Diabetes And Atherogenic Dyslipidemia Says International Academic Foundation
Cardiovascular risk can be reduced by an additional 31 percent in type 2 diabetes patients with atherogenic dyslipidemia, the common combination of elevated triglycerides (TG, 204 mg/dL or 2.3 mmol/L or higher) and low levels of high-density lipoprotein cholesterol (HDL-C, 34 mg/dL or 0.88 mmol/L or lower). This is achieved by adding fenofibrate to simvastatin... (Source: Cardiovascular / Cardiology News From Medical News Today)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Get the very latest Swine Flu news via the MedWorm <b><a href="http://www.medworm.com/rss/search.php?qu=%2Bswine+%2B%28influenza+flu%29&t=Swine+Flu&f=infectiousdiseases&r=Any&o=d" target ="_self">Swine Flu RSS news feed</a></b> - updated hourly from thousands of authoritative health and news sources.</p></div>
Search For New Diabetes And Heart Disease Treatments Unresolved
Treatment with the anti-hypertensive drug valsartan (Diovan) led to a modest reduction in the development of type 2 diabetes but did not significantly reduce cardiovascular events in patients with impaired glucose tolerance, according to researchers at Duke University Medical Center and the University of Oxford... (Source: Hypertension News From Medical News Today)
ACCORD Lipid Study Brings New Hope To People With Type 2 Diabetes And Atherogenic Dyslipidemia Says International Academic Foundation
Cardiovascular risk can be reduced by an additional 31 percent in type 2 diabetes patients with atherogenic dyslipidemia, the common combination of elevated triglycerides (TG, 204 mg/dL or 2.3 mmol/L or higher) and low levels of high-density lipoprotein cholesterol (HDL-C, 34 mg/dL or 0.88 mmol/L or lower). This is achieved by adding fenofibrate to simvastatin. Only 20 of these patients need to be treated for 5 years to prevent one cardiovascular event... (Source: Health News from Medical News Today)
Search For New Diabetes And Heart Disease Treatments Unresolved
Treatment with the anti-hypertensive drug valsartan (Diovan) led to a modest reduction in the development of type 2 diabetes but did not significantly reduce cardiovascular events in patients with impaired glucose tolerance, according to researchers at Duke University Medical Center and the University of Oxford. They jointly reported results at the American College of Cardiology meeting from the world's first study designed to find ways to control the progression to diabetes and cardiovascular disease in people at risk... (Source: Health News from Medical News Today)
Amylin, Lilly And Alkermes Receive Complete Response Letter From FDA For Exenatide Once Weekly Submission
Amylin Pharmaceuticals, Inc. (Nasdaq: AMLN), Eli Lilly and Company (NYSE: LLY) and Alkermes, Inc. (Nasdaq: ALKS) announced that the U.S. Food and Drug Administration (FDA) has issued a complete response letter regarding the New Drug Application (NDA) for BYDUREON? (exenatide for extended-release injectable suspension). In the complete response letter there are no requests for new pre-clinical or clinical trials... (Source: Health News from Medical News Today)
Amylin, Lilly And Alkermes Receive Complete Response Letter From FDA For Exenatide Once Weekly Submission
Amylin Pharmaceuticals, Inc. (Nasdaq: AMLN), Eli Lilly and Company (NYSE: LLY) and Alkermes, Inc. (Nasdaq: ALKS) announced that the U.S. Food and Drug Administration (FDA) has issued a complete response letter regarding the New Drug Application (NDA) for BYDUREON? (exenatide for extended-release injectable suspension)... (Source: Diabetes News From Medical News Today)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Get the very latest Swine Flu news via the MedWorm <b><a href="http://www.medworm.com/rss/search.php?qu=%2Bswine+%2B%28influenza+flu%29&t=Swine+Flu&f=infectiousdiseases&r=Any&o=d" target ="_self">Swine Flu RSS news feed</a></b> - updated hourly from thousands of authoritative health and news sources.</p></div>
Alzheimer's Disease-Like Changes Discovered In Elderly People Without The Disease
The emergence of multiple new brain imaging technologies and the combined application of these new approaches is helping to create new insights into aging and Alzheimer's disease. One of the hallmarks of Alzheimer's disease is the deposition of amyloid beta protein in clumps or "plaques" within the brain. These plaques can be measured in humans with PET scans that use a chemical marker or radiotracer called 11C-PIB. It was long thought that the formation of plaques injured and perhaps even caused the death of nerve cells in the brain... (Source: Health News from Medical News Today)
The Control Of Fatty Acid Uptake By Muscle Cells
A new study from the Swedish medical university Karolinska Institutet shows that the blood vessels and muscles of the heart can regulate the uptake of fatty acids that we ingest through meat, milk products and other food. The researchers behind the study have also identified the way in which regulation is governed by the muscles themselves. The results, which are published in the scientific journal Nature, open the way for new forms of treatment for pathological fat accumulation in the muscles which, in turn, increases the risk of type II (adult) diabetes and cardiovascular disease... (Source: Health News from Medical News Today)
FDA Requests Additional Information Regarding AFREZZA? In Complete Response Letter To MannKind
MannKind Corporation (Nasdaq:MNKD) announced that it has received a Complete Response letter from the U.S. Food & Drug Administration (FDA) regarding the New Drug Application (NDA) for AFREZZA? (insulin human [rDNA origin]) Inhalation Powder for the treatment of adult patients with type 1 and type 2 diabetes mellitus for the control of hyperglycemia. A Complete Response letter is issued by the FDA's Center for Drug Evaluation and Research when the review of a file is completed and questions remain that preclude the approval of the NDA in its current form... (Source: Health News from Medical News Today)
Minorities At Greater Risk For Kidney Disease
Certain ethnic minorities, including African Americans and Hispanics, are at a higher risk than the general population for developing potentially life-threatening chronic kidney disease (CKD) , which has been linked to higher rates of diabetes and high blood pressure, according to the National Kidney Foundation (NKF)... (Source: Health News from Medical News Today)
The Control Of Fatty Acid Uptake By Muscle Cells
A new study from the Swedish medical university Karolinska Institutet shows that the blood vessels and muscles of the heart can regulate the uptake of fatty acids that we ingest through meat, milk products and other food. The researchers behind the study have also identified the way in which regulation is governed by the muscles themselves... (Source: Diabetes News From Medical News Today)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Get the very latest Swine Flu news via the MedWorm <b><a href="http://www.medworm.com/rss/search.php?qu=%2Bswine+%2B%28influenza+flu%29&t=Swine+Flu&f=infectiousdiseases&r=Any&o=d" target ="_self">Swine Flu RSS news feed</a></b> - updated hourly from thousands of authoritative health and news sources.</p></div>
FDA Requests Additional Information Regarding AFREZZA? In Complete Response Letter To MannKind
MannKind Corporation (Nasdaq:MNKD) announced that it has received a Complete Response letter from the U.S. Food & Drug Administration (FDA) regarding the New Drug Application (NDA) for AFREZZA? (insulin human [rDNA origin]) Inhalation Powder for the treatment of adult patients with type 1 and type 2 diabetes mellitus for the control of hyperglycemia... (Source: Diabetes News From Medical News Today)
Alzheimer's Disease-Like Changes Discovered In Elderly People Without The Disease
The emergence of multiple new brain imaging technologies and the combined application of these new approaches is helping to create new insights into aging and Alzheimer's disease. One of the hallmarks of Alzheimer's disease is the deposition of amyloid beta protein in clumps or "plaques" within the brain... (Source: Alzheimer's / Dementia News From Medical News Today)
Minorities At Greater Risk For Kidney Disease
Certain ethnic minorities, including African Americans and Hispanics, are at a higher risk than the general population for developing potentially life-threatening chronic kidney disease (CKD) , which has been linked to higher rates of diabetes and high blood pressure, according to the National Kidney Foundation (NKF)... (Source: Urology / Nephrology News From Medical News Today)
Sales surge pushes Axis-Shield to profit
The diagnostic group said sales of its diabetes-testing Afinion machine rose by 72% in 2009 and announced that it had bought back the US marketing rights to the device (Source: FT.com - Drugs and Healthcare)
Publix Pharmacies Launch Free Metformin For Type II Diabetes Patients As New Diabetes Program Debuts
Publix Pharmacies launched the first phase of a new diabetes management system. The program is a multi-faceted program established to assist customers and associates living with diabetes in managing their medication, compliance, monitoring, education, nutrition and exercise. In its first phase, this one-of-a-kind program offers diabetic patients free medication, online resources and the benefit of knowledgeable pharmacists. At the core of the program is the free generic immediate-release metformin (500 mg, 850 mg or 1,000 mg) - the generic form of the drug Glucophage... (Source: Health News from Medical News Today)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Get the very latest Swine Flu news via the MedWorm <b><a href="http://www.medworm.com/rss/search.php?qu=%2Bswine+%2B%28influenza+flu%29&t=Swine+Flu&f=infectiousdiseases&r=Any&o=d" target ="_self">Swine Flu RSS news feed</a></b> - updated hourly from thousands of authoritative health and news sources.</p></div>
Publix Pharmacies Launch Free Metformin For Type II Diabetes Patients As New Diabetes Program Debuts
Publix Pharmacies launched the first phase of a new diabetes management system. The program is a multi-faceted program established to assist customers and associates living with diabetes in managing their medication, compliance, monitoring, education, nutrition and exercise... (Source: Diabetes News From Medical News Today)
Difficulty trusting and reaching out to others may shorten diabetes patients' lives
(University of Washington) Being overly cautious or dismissive in relating to others, including health-care providers, may shorten the lives of people with diabetes. In a five-year study, diabetes patients who had a lower propensity to reach out to others had a higher mortality rate than those who felt comfortable seeking support. There are approaches that health-care professionals might try to improve collaboration with patients who have an independent relationship style. (Source: EurekAlert! - Social and Behavioral Science)
Elderly woman died after botched operation from German doctor
An elderly woman died after a German locum doctor carried out one of the "worst botched operations" ever seen in a British hospital, an inquest heard yesterday. (Source: Telegraph Health)
Staples for skin closure in surgery
(Source: BMJ Online First)
Shrinking budgets, improving care: Simplify processes and engage with patients
(Source: BMJ Online First)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Get the very latest Swine Flu news via the MedWorm <b><a href="http://www.medworm.com/rss/search.php?qu=%2Bswine+%2B%28influenza+flu%29&t=Swine+Flu&f=infectiousdiseases&r=Any&o=d" target ="_self">Swine Flu RSS news feed</a></b> - updated hourly from thousands of authoritative health and news sources.</p></div>
Prevalence of the Metabolic Syndrome among rural original adults in NingXia, China
Background Metabolic syndrome (MS) is combination of medical disorders that increase people's risk for cardiovascular disease and diabetes mellitus. Little data exists on the prevalence of MS of rural original adults in Ningxia of China.Methods A cross-sectional survey method was used and the participants were interviewed by trained health workers under a structured questionnaire in rural of Ningxia in 2008. The number of research subjects was 1612. MS was defined by International Diabetes Federation IDF (2005).Results The age-adjusted prevalence of the metabolic syndrome was 11.8%, whereas ethnic-specific prevalence was 10.3% in Han ethnic group and 13.7% in Hui ethnic group. Components of MS and MS were more common in Hui ethnic group than Han ethnic group. The mean levels and prevalence...
Program opens girls&#8217; eyes to science
After Keisha Barreto saw many of her relatives suffer serious health issues, she knew she wanted to be a doctor. "My mother has diabetes, my uncle died from heart problems and there is cancer in my family," said Barreto, a high school junior. "If there's... (Source: OrlandoSentinel: Medical Research)
Association between physical activity and metabolic syndrome: a cross sectional survey in adolescents in Ho Chi Minh City, Vietnam
Conclusions: A more physically active lifestyle appears to be associated with a lower odds of metabolic syndrome in Vietnamese adolescents. Socio-economic status should be taken into account when planning interventions to prevent adolescent metabolic syndrome. (Source: BMC Public Health - Latest articles)
Durable responses with the metronomic rituximab and thalidomide plus prednisone, etoposide, procarbazine, and cyclophosphamide regimen in elderly patients with recurrent mantle cell lymphoma
Targeting the tumor microenvironment and angiogenesis is a novel lymphoma therapeutic strategy. The authors report safety, activity, and angiogenic profiling results with the rituximab and thalidomide plus prednisone, etoposide, procarbazine, and cyclophosphamide (RT-PEPC) regimen in patients with recurrent mantle cell lymphoma (MCL).RT-PEPC included induction (Months 1-3) of rituximab 4 times weekly, daily thalidomide (50 mg), and PEPC followed by maintenance thalidomide (100 mg), oral PEPC titrated to the neutrophil count, and rituximab every 4 months. Endpoints included safety, efficacy, quality of life (QoL), and translational studies, including tumor angiogenic phenotyping, plasma vascular endothelial growth factor (VEGF), and circulating endothelial cells.Twenty-five patients were en...
Being next of kin to an elderly person with cancer
Conclusion: With the onset of a serious illness, all next of kin are greatly affected in many ways but especially by changes in their roles, without, however, being prepared. The phenomenon of time seems to have significant meaning to the next of kin, although it may be perceived differently from the perspective of healthcare professionals than from that of next of kin. (Source: Scandinavian Journal of Caring Sciences)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Get the very latest Swine Flu news via the MedWorm <b><a href="http://www.medworm.com/rss/search.php?qu=%2Bswine+%2B%28influenza+flu%29&t=Swine+Flu&f=infectiousdiseases&r=Any&o=d" target ="_self">Swine Flu RSS news feed</a></b> - updated hourly from thousands of authoritative health and news sources.</p></div>
Wednesday 17 March
Hospitals should axe thousands of beds: Nearly 30,000 hospital beds in England should be axed to save money and improve care, according to the think-tank Reform. The study, Fewer Hospitals and More Competition says the NHS focus should move away from hospital treatment as more people suffer from conditions, such as diabetes, which can be treated at home. It says a quarter of beds could be axed to fund more personalised treatment. Tom Sandford, Director of RCN England said: “Simply slashing bed numbers without planning for the long term would be completely irresponsible”. (Source: Royal College of Nursing News Alert)
Early-life determinants of overweight and obesity: a review of systematic reviews
The aim of this paper was to review the evidence for early-life (from conception to 5 years of age) determinants of obesity. The design is review of published systematic reviews. Data sources included Medline, Embase, Web of Science, Cochrane Library, CINAHL, PsycINFO. Identification of 22 eligible reviews from a database of 12 021 independent publications. Quality of selected reviews assessed using the Assessment of Multiple Systematic Reviews score. Articles published after the reviews were used to confirm results. No review was classified as high quality, 11 as moderate and 11 as low. Factors associated with later overweight and obesity: maternal diabetes, maternal smoking, rapid infant growth, no or short breastfeeding, obesity in infancy, short sleep duration, (Source: Obesity Reviews...
Sernova Announces Interim Results From Key Preclincal Study With Its Proprietary Cell Pouch SystemTM
Sernova Corp. (TSX VENTURE:SVA) today reported interim results from a key porcine diabetes study evaluating the safety and efficacy of the Cell Pouch System?. Interim results, to be presented at the American Society of Artificial Internal Organs 56th Annual Conference, Baltimore, MD, May 27th-29th in a podium presentation, confirm that the Cell Pouch System? establishes a biological environment capable of preserving the functionality of therapeutic cells... (Source: Health News from Medical News Today)
Sernova Announces Interim Results From Key Preclincal Study With Its Proprietary Cell Pouch SystemTM
Sernova Corp. (TSX VENTURE:SVA) today reported interim results from a key porcine diabetes study evaluating the safety and efficacy of the Cell Pouch System?... (Source: Diabetes News From Medical News Today)
FDA Eyes Improvements for Diabetics' Glucose Devices
U.S. health regulators are taking a closer look at how well devices used by diabetics to monitor their blood sugars work, seeking possible changes for device makers to help make them more reliable. Source: Reuters Health Related MedlinePlus Pages: Diabetes, Diabetes Type 1, Medical Device Safety (Source: MedlinePlus Health News)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Get the very latest Swine Flu news via the MedWorm <b><a href="http://www.medworm.com/rss/search.php?qu=%2Bswine+%2B%28influenza+flu%29&t=Swine+Flu&f=infectiousdiseases&r=Any&o=d" target ="_self">Swine Flu RSS news feed</a></b> - updated hourly from thousands of authoritative health and news sources.</p></div>
Leveraging leptin for type I diabetes? [Commentaries]
(Source: Proceedings of the National Academy of Sciences)
Feature Article: Leptin therapy in insulin-deficient type I diabetes [Medical_Sciences]
In nonobese diabetic mice with uncontrolled type 1 diabetes, leptin therapy alone or combined with low-dose insulin reverses the catabolic... (Source: Proceedings of the National Academy of Sciences)
Improving Sensorimotor Function after Stroke in aged rats (2010-03-30)
&lt;span style=&quot;font-size: 11pt;::Stroke is caused by clots and bleeds within the brain and is one of the leading causes of disability in the UK, particularly afflicting the elderly. There are no fully restorative therapies for stroke. My laboratory has recently developed a novel model of stroke in aged rats and we have successfully screened two candidate therapies using this model. Both ther (Source: Institute of Psychiatry | Events)
Abnormal Ankle-Brachial Index an Indicator of Cardiovascular Events in Low-Risk Elderly
An abnormal ankle-brachial index predicts risk for myocardial infarction in elderly people with low to intermediate Framingham Risk Scores. Medscape Medical News (Source: Medscape Today Headlines)
PPAR/RXR Regulation of Fatty Acid Metabolism and Fatty Acid &#x03C9;-Hydroxylase (CYP4) Isozymes: Implications for Prevention of Lipotoxicity in Fatty Liver Disease
Fatty liver disease is a common lipid metabolism disorder influenced by the combination of individual genetic makeup, drug exposure, and life-style choices that are frequently associated with metabolic syndrome, which encompasses obesity, dyslipidemia, hypertension, hypertriglyceridemia, and insulin resistant diabetes. Common to obesity related dyslipidemia is the excessive storage of hepatic fatty acids (steatosis), due to a decrease in mitochondria &#x03B2;-oxidation with an increase in both peroxisomal &#x03B2;-oxidation, and microsomal &#x03C9;-oxidation of fatty acids through peroxisome proliferator activated receptors (PPARs). How steatosis increases PPAR&#x03B1; activated gene expression of fatty acid transport proteins, peroxisomal and mitochondrial fatty acid &#x03B2;-oxidation an...<div id="medworm"><p><b><i>MedWorm Message:</i></b> Get the very latest Swine Flu news via the MedWorm <b><a href="http://www.medworm.com/rss/search.php?qu=%2Bswine+%2B%28influenza+flu%29&t=Swine+Flu&f=infectiousdiseases&r=Any&o=d" target ="_self">Swine Flu RSS news feed</a></b> - updated hourly from thousands of authoritative health and news sources.</p></div>
Old Arthritis Drug May Help Diabetics (CME/CE)
A drug widely used to treat joint pain improved blood glucose control in patients with type 2 diabetes, researchers said. (Source: MedPage Today Nephrology)
Type 2 Diabetes Study: Drugs Don't Cut Heart Disease Risk
New data suggest that aggressive drug treatments to reduce known heart-disease risk factors don't actually help Type 2 diabetes patients. Why? And what now? (Source: TIME.com: Top Science and Health Stories)
Mylan, Takeda Reach Agreement Over Diabetes Drugs
From Associated Press (March 16, 2010) PITTSBURGH -- Generic drug maker Mylan Inc. has reached settlement agreements with Japanese drug maker Takeda Pharmaceuticals over rights to launch generic versions of two Type 2 diabetes treatments. Mylan... (Source: Drugs.com - Pharma News)
Emmi - Roth Käse USA Announces Recall of Spreadables brand Crab Creole and Shrimp Scampi Cheese Spreads
Emmi - Roth Käse USA is voluntarily recalling approximately 1,971 total individual containers of 7 ounce and 2 pound Spreadables brand Crab Creole and Shrimp Scampi cheese spreads because they have the potential to be contaminated with Salmonella, an organism which can cause serious and sometimes fatal infections in young children, frail or elderly people, and others with weakened immune systems. Healthy persons infected with Salmonella often experience fever, diarrhea (which may be bloody), nausea, vomiting and abdominal pain. (Source: Food and Drug Administration)
Globe article on the cost of care at Children?s
A Boston Globe article this morning brought the cost of care here at Children?s Hospital Boston into question, saying, among other things, that ?Children?s charges the highest fees for both outpatient and inpatient care.? It?s based on data by Harvard Pilgrim Health Care (HPHC) that we don?t feel accurately reflects the care that we provide. While the writer, Liz Kowalczyk, did say that because about 30 percent of our patients are on Medicaid, we have to ?make up the lost revenue from private insurers,? I don?t think she went far enough in explaining why our costs tend to be higher than other hospitals in the state. First and most important, Children?s is the only freestanding children?s hospital on the Globe?s list, so comparing the care we deliver to that of hospi...<div id="medworm"><p><b><i>MedWorm Message:</i></b> Get the very latest Swine Flu news via the MedWorm <b><a href="http://www.medworm.com/rss/search.php?qu=%2Bswine+%2B%28influenza+flu%29&t=Swine+Flu&f=infectiousdiseases&r=Any&o=d" target ="_self">Swine Flu RSS news feed</a></b> - updated hourly from thousands of authoritative health and news sources.</p></div>
Valsartan delays progression to type 2 diabetes
Results from a landmark study involving more than 9,000 people showed that the high blood pressure medicine valsartan delayed progression to type 2 diabetes in patients with cardiovascular disease or risk factors and impaired glucose tolerance (IGT). (Source: Pharmacy Europe)
Obesity and lung inflammation
The prevalence of obesity has increased dramatically worldwide, predisposing individuals to an increased risk of morbidity and mortality due to cardiovascular disease and type 2 diabetes. Less recognized is the fact that obesity may play a significant role in the pathogenesis of pulmonary diseases through mechanisms that may involve proinflammatory mediators produced in adipose tissue that contribute to a low-grade state of systemic inflammation. In animal models, inflammatory responses in the lung have been shown to influence the production of the adipocytokines, leptin and adiponectin, cytokines, acute phase proteins, and other mediators produced by adipose tissue that may participate in immune responses of the lung. An increased adipose tissue mass may also influence susceptibility to p...
BES: Testosterone Gel Improves Diabetes in Hypogonadal Men (CME/CE)
MANCHESTER, England (MedPage Today) -- Topical testosterone replacement reduced insulin resistance and glycated hemoglobin in men who were deficient in the hormone and at risk for, or diagnosed with type 2 diabetes, researchers reported here. (Source: MedPage Today Cardiovascular)
Generex Oral-lyn(TM) Presentation at CODHy Congress
WORCESTER, Mass., March 16, 2010 (GLOBE NEWSWIRE) -- Generex Biotechnology Corporation (Nasdaq:GNBT) (www.generex.com), the leader in drug delivery for metabolic diseases through the inner lining of the mouth, today announced that Philip Raskin, MD, of The University of Texas Southwestern Medical Center in Dallas, Texas, made a presentation in respect of Generex Oral-lyn(tm), the Company's proprietary buccal insulin spray product, at The Latin America Congress on Controversies to Consensus in Diabetes, Obesity and Hypertension (CODHy) held in Buenos Aires, Argentina, March 11-14, 2010 (www.comtecmed.com/Codhy/argentina). (Source: Medical News (via PRIMEZONE))
Seniors And Driving
Public safety should win against personal choice especially when it comes to elderly seniors who shouldn't drive, states an editorial in CMAJ (Canadian Medical Association Journal). Seniors can be the safest drivers but that decreases with age as a growing number of medical conditions can lower a person's ability to drive. By 2025, one in four Canadians will be 65 or older... (Source: Public Health News From Medical News Today)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Get the very latest Swine Flu news via the MedWorm <b><a href="http://www.medworm.com/rss/search.php?qu=%2Bswine+%2B%28influenza+flu%29&t=Swine+Flu&f=infectiousdiseases&r=Any&o=d" target ="_self">Swine Flu RSS news feed</a></b> - updated hourly from thousands of authoritative health and news sources.</p></div>
Seniors And Driving
Public safety should win against personal choice especially when it comes to elderly seniors who shouldn't drive, states an editorial in CMAJ (Canadian Medical Association Journal). Seniors can be the safest drivers but that decreases with age as a growing number of medical conditions can lower a person's ability to drive. By 2025, one in four Canadians will be 65 or older... (Source: Health News from Medical News Today)
New Research Reveals Potential New Drug For Type 2 Diabetes
An experimental oral drug has lowered blood sugar levels and inflammation in mice with Type 2 diabetes, suggesting that the medication could someday be added to the arsenal of drugs used by millions of Americans with this disease, according to new research. The drug consists of a synthetic molecule that stops the biological activity of a protein called macrophage migration inhibitory factor, or MIF. This protein is implicated in a number of diseases because it is associated with the production of inflammation in the body... (Source: Health News from Medical News Today)
More Support For Health Benefits Of Coffee
Multitudes of people worldwide begin each day with a cup of steaming hot coffee. Although it is sometimes referred to as "the devil's brew," coffee contains several nutrients (eg, calcium) as well as hundreds of potentially biologically active compounds (eg, polyphenols) that may promote health. For instance, observational studies have suggested a beneficial link between coffee consumption and type 2 diabetes. Determining whether or not this association is causative, however, requires controlled intervention trials... (Source: Health News from Medical News Today)
New Research Reveals Potential New Drug For Type 2 Diabetes
An experimental oral drug has lowered blood sugar levels and inflammation in mice with Type 2 diabetes, suggesting that the medication could someday be added to the arsenal of drugs used by millions of Americans with this disease, according to new research... (Source: Biology / Biochemistry News From Medical News Today)
King's Fund sets out social care funding proposals
Elderly people who need social care should foot part of the bill so current standards can be maintained as costs soar over the next 15 years, according to a new study. (Source: HSJ)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Get the very latest Swine Flu news via the MedWorm <b><a href="http://www.medworm.com/rss/search.php?qu=%2Bswine+%2B%28influenza+flu%29&t=Swine+Flu&f=infectiousdiseases&r=Any&o=d" target ="_self">Swine Flu RSS news feed</a></b> - updated hourly from thousands of authoritative health and news sources.</p></div>
Diabetes Trial: Drug Treatment May Not Cut Heart Disease
New data suggest that aggressive drug treatments to reduce known heart-disease risk factors don't actually help diabetes patients. Why? And what now? (Source: TIME.com: Top Science and Health Stories)
Diabetes' link to eating disorders explored
Diabetics, under the gun to better manage their disease by controlling their food intake and weight, may find themselves in the sticky wicket of needing treatment that makes them hungry, researchers said. (Source: ScienceDaily Headlines)
Partners reducing effects of diabetes (PREDICT): a diabetes prevention physical activity and dietary intervention through African-American churches
Type 2 diabetes is epidemic in the United States with greater incidence rates in African-American communities. Lifestyle interventions during the phase of insulin resistance mitigate cardiovascular risk and prevent diabetes. The primary aim of this study is to test the impact of a Community Health Advisor (CHA)-based diabetes prevention controlled intervention in urban African-American communities. In this controlled trial, church congregants in New Haven, CT, receiving a 1-year CHA-led diabetes prevention intervention were compared with church congregants in Bridgeport, CT, who did not receive an intervention. Outcome measures included physical activity, dietary pattern, anthropometric measure, social support, diabetes knowledge, nutrition and exercise self-efficacy. The results indicate ...
The role of collective efficacy in exercise adherence: a qualitative study of spousal support and Type 2 diabetes management
Adhering to increased exercise is often reported as one of the greatest challenges facing adults living with diabetes, a perception shared by the married middle-aged and older adults living with diabetes who participated in this study. Understanding how that challenge can best be met is both research and program relevant. Drawing on the social cognitive theory and social support literature, this qualitative study explored the powerful couple relationship in Type 2 diabetes management. The overarching goal of this paper was to illuminate the potentially key role of collective efficacy in exercise adherence in order to develop and test interventions that provide more effective supports for adults living with diabetes. Analyses revealed three core themes used by the couples to describe their ...
Lifestyle And Diet Still Best Ways To Help Prevent Type 2 Diabetes
Researchers looking at whether using a drug that lowers blood pressure (Valsartan) or a drug that lowers blood glucose levels (Nateglinide) could prevent Type 2 diabetes from developing found no great difference in the number of people who went on to develop the condition when prescribed either drug compared with the people who were prescribed a dummy pill. The drugs were also not successful in preventing heart attacks and strokes, which are complications of Type 2 diabetes. All the people taking part in the study had high blood glucose levels... (Source: Health News from Medical News Today)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Get the very latest Swine Flu news via the MedWorm <b><a href="http://www.medworm.com/rss/search.php?qu=%2Bswine+%2B%28influenza+flu%29&t=Swine+Flu&f=infectiousdiseases&r=Any&o=d" target ="_self">Swine Flu RSS news feed</a></b> - updated hourly from thousands of authoritative health and news sources.</p></div>
Study Shows Superior Efficacy For TAXUS(R) Express(R) Stents At One Year Compared To Bare-Metal Stents In Diabetic Patients Experiencing Heart Attack
Boston Scientific Corporation (NYSE: BSX) announced results from an analysis of one-year subset data from the HORIZONS AMI trial assessing the impact of diabetes on clinical and angiographic outcomes in heart attack patients treated with the TAXUS® Express2? Paclitaxel-Eluting Stent System or the Express® bare-metal stent... (Source: Health News from Medical News Today)
Neuroimaging Study Describes Alzheimer's Disease Like Changes In Elderly People Without The Disease
In a new study published in Biological Psychiatry, by Elsevier, researchers have related the findings that are emerging from PET-PIB imaging to changes in the function of brain circuits. The emergence of multiple new brain imaging technologies and the combined application of these new approaches is helping to create new insights into aging and Alzheimer's disease. One of the hallmarks of Alzheimer's disease is the deposition of amyloid beta protein in clumps or "plaques" within the brain... (Source: Health News from Medical News Today)
Generic Drug For Type 2 Diabetes Passes Next Clinical Hurdle
Clinical studies of a generic drug called salsalate, widely prescribed for arthritis, now provide early promising results that it may be useful for the treatment of patients with type 2 diabetes as well. Salsalate is an atypical non-steroidal anti-inflammatory agent that is chemically similar to aspirin but a bit easier on the stomach. In a three-month trial of people with type 2 diabetes that was led by Joslin Diabetes Center researchers, those who took the drug showed significantly improved blood glucose levels... (Source: Health News from Medical News Today)
Lifestyle And Diet Still Best Ways To Help Prevent Type 2 Diabetes
Researchers looking at whether using a drug that lowers blood pressure (Valsartan) or a drug that lowers blood glucose levels (Nateglinide) could prevent Type 2 diabetes from developing found no great difference in the number of people who went on to develop the condition when prescribed either drug compared with the people who were prescribed a dummy pill... (Source: Diabetes News From Medical News Today)
Study Shows Superior Efficacy For TAXUS(R) Express(R) Stents At One Year Compared To Bare-Metal Stents In Diabetic Patients Experiencing Heart Attack
Boston Scientific Corporation (NYSE: BSX) announced results from an analysis of one-year subset data from the HORIZONS AMI trial assessing the impact of diabetes on clinical and angiographic outcomes in heart attack patients treated with the TAXUS® Express2? Paclitaxel-Eluting Stent System or the Express® bare-metal stent... (Source: Diabetes News From Medical News Today)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Get the very latest Swine Flu news via the MedWorm <b><a href="http://www.medworm.com/rss/search.php?qu=%2Bswine+%2B%28influenza+flu%29&t=Swine+Flu&f=infectiousdiseases&r=Any&o=d" target ="_self">Swine Flu RSS news feed</a></b> - updated hourly from thousands of authoritative health and news sources.</p></div>
Generic Drug For Type 2 Diabetes Passes Next Clinical Hurdle
Clinical studies of a generic drug called salsalate, widely prescribed for arthritis, now provide early promising results that it may be useful for the treatment of patients with type 2 diabetes as well. Salsalate is an atypical non-steroidal anti-inflammatory agent that is chemically similar to aspirin but a bit easier on the stomach... (Source: Diabetes News From Medical News Today)
Neuroimaging Study Describes Alzheimer's Disease Like Changes In Elderly People Without The Disease
In a new study published in Biological Psychiatry, by Elsevier, researchers have related the findings that are emerging from PET-PIB imaging to changes in the function of brain circuits. The emergence of multiple new brain imaging technologies and the combined application of these new approaches is helping to create new insights into aging and Alzheimer's disease... (Source: Alzheimer's / Dementia News From Medical News Today)
Researcher urges caution in reducing blood pressure
For patients with diabetes and heart disease, less isn't always more &#8212; at least when it comes to blood pressure. New data show an increased risk of heart attack, stroke or death for patients having blood pressure deemed too high &#8212; or too low,... (Source: OrlandoSentinel: Medical Research)
UNC's Dr. John Buse To Receive National Award For Clinical Excellence
John B. Buse, M.D., Ph.D., has been selected to receive a Clinical Excellence award at the Castle Connolly National Physician of the Year Awards ceremony. Buse is a professor in the University of North Carolina at Chapel Hill School of Medicine, chief of the division of endocrinology and metabolism and director of the UNC Diabetes Care Center... (Source: Health News from Medical News Today)
Mayo Clinic Proceedings Study Finds Link Between Hypoglycemia And Mortality Rates In Critically Ill
In a study published in the March issue of Mayo Clinic Proceedings, researchers report that they have found a link between mild to moderate hypoglycemia (low blood sugar) and mortality in critically ill patients. The multicenter study involved six medical centers from Australia, New Zealand and Japan. The purpose of the study was to understand the epidemiology, severity, duration, recovery and outcome associations of hypoglycemia in critically ill patients... (Source: Health News from Medical News Today)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Get the very latest Swine Flu news via the MedWorm <b><a href="http://www.medworm.com/rss/search.php?qu=%2Bswine+%2B%28influenza+flu%29&t=Swine+Flu&f=infectiousdiseases&r=Any&o=d" target ="_self">Swine Flu RSS news feed</a></b> - updated hourly from thousands of authoritative health and news sources.</p></div>
Mayo Clinic Proceedings Study Finds Link Between Hypoglycemia And Mortality Rates In Critically Ill
In a study published in the March issue of Mayo Clinic Proceedings, researchers report that they have found a link between mild to moderate hypoglycemia (low blood sugar) and mortality in critically ill patients. The multicenter study involved six medical centers from Australia, New Zealand and Japan... (Source: Diabetes News From Medical News Today)
UNC's Dr. John Buse To Receive National Award For Clinical Excellence
John B. Buse, M.D., Ph.D., has been selected to receive a Clinical Excellence award at the Castle Connolly National Physician of the Year Awards ceremony. Buse is a professor in the University of North Carolina at Chapel Hill School of Medicine, chief of the division of endocrinology and metabolism and director of the UNC Diabetes Care Center... (Source: Public Health News From Medical News Today)
Nearly 2 million Californians lost health insurance during recession, study finds
Nearly 2 million Californians lost their health insurance during 2008 and 2009 &mdash; years characterized by a deep recession and mass layoffs &mdash; bringing the total number of uninsured in the state to more than 8 million, according to new estimates from the UCLA Center for Health Policy Research. &nbsp; The number represents a 25 percent increase in the number of uninsured since 2007, when 6.4 million Californians lacked insurance, according to the authors of the new policy brief, "Number of Uninsured Jumped to More Than Eight Million from 2007 to 2009." Today, nearly one-quarter of all adult Californians lack health insurance. &nbsp; "These estimates help us understand the scale of the damage inflicted on California over the last two years," said Shana Alex Lavarreda, the center's d...
Salsalate May Help Treat Type 2 Diabetes
Title: Salsalate May Help Treat Type 2 DiabetesCategory: Health NewsCreated: 3/16/2010 10:27:00 AMLast Editorial Review: 3/16/2010 10:27:48 AM (Source: MedicineNet Diabetes General)
ED, Heart Disease May Be Deadly Duo
Title: ED, Heart Disease May Be Deadly DuoCategory: Health NewsCreated: 3/16/2010 9:59:00 AMLast Editorial Review: 3/16/2010 9:59:28 AM (Source: MedicineNet Diabetes General)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Get the very latest Swine Flu news via the MedWorm <b><a href="http://www.medworm.com/rss/search.php?qu=%2Bswine+%2B%28influenza+flu%29&t=Swine+Flu&f=infectiousdiseases&r=Any&o=d" target ="_self">Swine Flu RSS news feed</a></b> - updated hourly from thousands of authoritative health and news sources.</p></div>
Boosting Vitamin D Can Do a Heart Good
Title: Boosting Vitamin D Can Do a Heart GoodCategory: Health NewsCreated: 3/15/2010 4:10:00 PMLast Editorial Review: 3/16/2010 (Source: MedicineNet Diabetes General)
Salsalate May Help Treat Type 2 Diabetes
Title: Salsalate May Help Treat Type 2 DiabetesCategory: Health NewsCreated: 3/16/2010 10:27:00 AMLast Editorial Review: 3/16/2010 10:27:48 AM (Source: MedicineNet Senior Health General)
Salsalate May Help Treat Type 2 Diabetes
(Source: eMedicineHealth.com)
AMA offers booklet on elderly driving
CHICAGO, March 16 (UPI) -- The American Medical Association has produced a guide for older drivers to help protect their lives and make roads safer, AMA officials say. (Source: Health News - UPI.com)
Vital Signs: Study Links Soda Price Increases to Better Health
Research found that when the price of a two-liter bottle went up, people consumed less, which was associated with a drop in weight and a lower risk for pre-diabetes. (Source: NYT)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Get the very latest Swine Flu news via the MedWorm <b><a href="http://www.medworm.com/rss/search.php?qu=%2Bswine+%2B%28influenza+flu%29&t=Swine+Flu&f=infectiousdiseases&r=Any&o=d" target ="_self">Swine Flu RSS news feed</a></b> - updated hourly from thousands of authoritative health and news sources.</p></div>
Landmark ACCORD Trial Finds Intensive Blood Pressure and Combination Lipid Therapies do not Reduce Combined Cardiovascular Events in Adults with Diabetes
Source: National Heart, Lung, and Blood Institute - Related MedlinePlus Page: Diabetes Complications (Source: MedlinePlus Health News)
Review call after GP's morphine deaths
A CORONER called for a review of GPs' medical practices after finding that high doses of morphine administered by an elderly doctor contributed to patients' deaths. (Source: Scotsman.com News - Health)
Socio-economic differences in life expectancy among persons with diabetes mellitus or myocardial infarction: results from the German MONICA/KORA study
Conclusion: This study shows that in Germany the differences in LE by socio-economic status are comparable to those found in other European countries, and that these differences seem to increase when diabetes mellitus or myocardial infarction are present. The statistical method used allows estimates of LE with relatively small datasets. (Source: BMC Public Health - Latest articles)
Elderly care costs set to double in the next 15 years
THE cost of social care for the elderly is set to double in the next 15 years just to maintain current standards, according to a report today by the King's Fund. (Source: Scotsman.com News - Health)
Reducing delirium in elderly patients with hip fracture: a multi-factorial intervention study
There is an evident need for improved management of elderly patients with trauma in order to avoid common and troublesome complications such as delirium. The aim of this study was to investigate whether an implementation of a multi-factorial program including intensified pre-hospital and perioperative treatment and care could reduce the incidence of delirium in elderly patients with hip fracture, cognitively intact at admission to the hospital. In addition, we explored the factors that characterize patients who developed delirium. A prospective, quasi-experimental design was used. A total of 263 patients with hip fracture ([ge]65 years), cognitively intact at admission, were consecutively included between April 2003 and April 2004. On 1 October 2003, a new program was introduced. All patie...<div id="medworm"><p><b><i>MedWorm Message:</i></b> Get the very latest Swine Flu news via the MedWorm <b><a href="http://www.medworm.com/rss/search.php?qu=%2Bswine+%2B%28influenza+flu%29&t=Swine+Flu&f=infectiousdiseases&r=Any&o=d" target ="_self">Swine Flu RSS news feed</a></b> - updated hourly from thousands of authoritative health and news sources.</p></div>
No benefit of lower blood pressure or lipid targets in type 2 diabetes
Read the full story on MD Consult: No benefit of lower blood pressure or lipid targets in type 2 diabetes (Source: MD Consult: News: Top Stories)
Dementia: Nostalgic songs and films can help sufferers
I NEVER know if tears are a good or a bad thing in my line of work," says singer Patricia Hammond. The 35-year-old Canadian has travelled the UK performing for elderly audiences in hospitals and retirement homes, (Source: Daily Express - Health)
Drugs in type 2 diabetes: their properties and recommended use
There are now six classes of oral antidiabetic drugs and a new class of injectable GLP-1 agonists in the drug therapy of type 2 diabetes, with metformin remaining the cornerstone of treatment. Our Drug review considers their mode of action, properties and recommended use, followed by sources of further information and an analysis of prescription data. Copyright © 2010 Wiley Interface Ltd (Source: Prescriber)
Pluripotent plasticity of stem cells and liver repopulation
Different types of stem cells have a role in liver regeneration or fibrous repair during and after several liver diseases. Otherwise, the origin of hepatic and/or extra-hepatic stem cells in reactive liver repopulation is under controversy. The ability of the human body to self-repair and replace the cells and tissues of some organs is often evident. It has been estimated that complete renewal of liver tissue takes place in about a year. Replacement of lost liver tissues is accomplished by proliferation of mature hepatocytes, hepatic oval stem cells differentiation, and sinusoidal cells as support. Hepatic oval cells display a distinct phenotype and have been shown to be a bipotential progenitor of two types of epithelial cells found in the liver, hepatocytes, and bile ductular cells. In g...
Mitigation of septic shock in mice and rhesus monkeys by human chorionic gonadotrophin-related oligopeptides
The marked improvement of several immune-mediated inflammatory diseases during pregnancy has drawn attention to pregnancy hormones as potential therapeutics for such disorders. Low molecular weight fractions derived from the pregnancy hormone human chorionic gonadotrophin (hCG) have remarkable potent immunosuppressive effects in mouse models of diabetes and septic shock. Based on these data we have designed a set of oligopeptides related to the primary structure of hCG and tested these in models of septic shock in mice and rhesus monkeys. We demonstrate that mice exposed to lipopolysaccharide (LPS) and treated subsequently with selected tri-, tetra-, penta- and hepta-meric oligopeptides (i.e. MTR, VVC, MTRV, LQGV, AQGV, VLPALP, VLPALPQ) are protected against fatal LPS-induced septic shock....<div id="medworm"><p><b><i>MedWorm Message:</i></b> Get the very latest Swine Flu news via the MedWorm <b><a href="http://www.medworm.com/rss/search.php?qu=%2Bswine+%2B%28influenza+flu%29&t=Swine+Flu&f=infectiousdiseases&r=Any&o=d" target ="_self">Swine Flu RSS news feed</a></b> - updated hourly from thousands of authoritative health and news sources.</p></div>
Self Care Campaign group report on cost of seeing GP for ailments that can be self-treated
Source: Self Care Campaign Area: News 'Self Care: An Ethical Imperative', a paper published by the Self Care Campaign group, presents the results of research on the impact that a dependency and demand-led culture is having on the NHS. According to the paper, seeing a GP for ailments that can be self-treated is estimated to cost £2 billion every year. Other findings from the paper include: &nbsp; .&nbsp;57 million GP consultations every year involve minor ailments which can be self-treated &nbsp; .&nbsp;Of these 57m consultations, 51.4m involve a minor ailments only, equating to 18% of GP workload &nbsp; .&nbsp;91% of these consultations end in a prescription, which cost the NHS £371 million annually &nbsp; .&nbsp;Treatment of 10 minor ailments account for 75% of GP consu...
Salsalate for blood glucose control?
Source: Ann Intern Med Area: News A small controlled trial suggests that salsalate, a derivative of salicylic acid that acts as a salicylate pro-drug, may improve blood glucose control in type 2 diabetes. &nbsp; There is some experimental evidence that salicylate may improve glycaemic control in type 2 diabetes: this trial aimed to determine what dose of salsalate, a salicylate pro-drug with no gastro-intestinal irritant effects, was beneficial in such patients. Participants were adults with type 2 diabetes: inclusion criteria were fasting plasma glucose concentrations of 12.5 mmol/L or less and haemoglobin A1c (HbA1c) levels of 7.0% to 9.5%, treated by diet, exercise, and oral medication at stable doses for at least 8 weeks. They were randomised to salsalate 3.0, 3.5, or 4.0 gm daily...
Dapagliflozin improves glycemic control and weight of Type 2 diabetics
Study results show that dapagliflozin treatment improves the glycemic control and body weight of both early and late-stage Type 2 diabetics. (Source: MedWire News - Diabetes)
Influence of general health and degree of surgical insult on long-term survival
This study investigated the relationship of American Society of Anesthesiologists Physical Status (ASA-PS) grade and degree of surgical insult to long-term postoperative survival.National death records to June 2007 were matched against records of patients undergoing elective surgery between January 1997 and December 2001. Stratified survival analysis was performed to allow baseline hazard functions to vary among four patient groups (15-64 years with no malignancy, at least 65 years with no malignancy, 15-64 years with malignancy and at least 65 years with malignancy).Of 8134 patients, 6185 (76·0 per cent) were alive after a median follow-up of 7·1 (range 0-10·5) years. The overall mortality rate was 3·62 (95 per cent confidence interval (c.i.) 3·46 to 3·78) per 100 person-years. The ...
[Research Article] Cholinergic Augmentation of Insulin Release Requires Ankyrin-B
The scaffolding protein ankyrin-B is needed for maximal insulin release and loss of function is a risk factor for diabetes. (Source: Signal Transduction Knowledge Environment)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Get the very latest Swine Flu news via the MedWorm <b><a href="http://www.medworm.com/rss/search.php?qu=%2Bswine+%2B%28influenza+flu%29&t=Swine+Flu&f=infectiousdiseases&r=Any&o=d" target ="_self">Swine Flu RSS news feed</a></b> - updated hourly from thousands of authoritative health and news sources.</p></div>
Millions of older ER patients got wrong Rx
ANN ARBOR, Mich., March 15 (UPI) -- Many elderly people treated in U.S. hospital emergency rooms are given one or more potentially inappropriate medications, researchers estimate. (Source: Health News - UPI.com)
Salsalate May Help Treat Type 2 Diabetes
Salsalate, a common pain reliever, may help people with type 2 diabetes control their blood sugar levels. (Source: WebMD Health)
Observatory: Seeking Safe Ways to Deliver Nitric Oxide in Medical Care
Researchers are investigating new methods for storing and releasing an important gas for those who do not produce enough of it. (Source: NYT &gt; Health)
To Cut Diabetes Heart Risks, Diet and Exercise May Beat Drugs
A 5-step action plan for lowering heart risks associated with diabetes. (Source: U.S. News - Health)
Salsalate As a Type 2 Diabetes Treatment? It Looks Promising
A longtime arthritis medicine could one day be an affordable diabetes treatment. (Source: U.S. News - Health)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Get the very latest Swine Flu news via the MedWorm <b><a href="http://www.medworm.com/rss/search.php?qu=%2Bswine+%2B%28influenza+flu%29&t=Swine+Flu&f=infectiousdiseases&r=Any&o=d" target ="_self">Swine Flu RSS news feed</a></b> - updated hourly from thousands of authoritative health and news sources.</p></div>
Drug Helps Diabetics, Trial Finds
A generic anti-inflammatory drug from the aspirin family helped patients in a clinical trial lower their blood sugar. (Source: NYT &gt; Health)
Arthritis Drug May Fight Diabetes, Too
Study finds that salsalate helps control blood sugar levels Source: HealthDay Related MedlinePlus Pages: Arthritis, Diabetes, Medicines (Source: MedlinePlus Health News)
Mortality and Morbidity Reduction by Primary Percutaneous Coronary Intervention Is Independent of the Patient's Age
Conclusions In this analysis of randomized trials, the reduction in clinical end points by PPCI was not influenced by age. Hence, age per se should not be considered an exclusion criterion for the application of PPCI. (Source: Journal of the American College of Cardiology: Cardiovascular Interventions)
Adding fat-lowering drug no help for diabetic hearts
ATLANTA (Reuters) - Adding a drug that lowers blood fats known as triglycerides to cholesterol-fighting statins provided no additional protection from heart attack, stroke and death from heart disease in patients with Type 2 diabetes, according to data from a large study. (Source: Reuters: Health)
Boosting Vitamin D Can Do a Heart Good
In those with low levels to start, odds eased for diabetes, cardio woes, study found Source: HealthDay Related MedlinePlus Pages: Heart Diseases--Prevention, Vitamin D (Source: MedlinePlus Health News)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Get the very latest Swine Flu news via the MedWorm <b><a href="http://www.medworm.com/rss/search.php?qu=%2Bswine+%2B%28influenza+flu%29&t=Swine+Flu&f=infectiousdiseases&r=Any&o=d" target ="_self">Swine Flu RSS news feed</a></b> - updated hourly from thousands of authoritative health and news sources.</p></div>
Hydroxyurea-Associated Dermatomyositis-like Eruption Demonstrating Abnormal Epidermal p53 Expression: A Potential Premalignant Manifestation of Chronic Hydroxyurea and UV Radiation Exposure [Observation]
Conclusions&nbsp; We suggest that dermatomyositis-like eruption and hydroxyurea-associated squamous dysplasia represent similar clinical manifestations of a common underlying chronic phototoxic process involving aberrant keratinocyte p53 expression mediated by hydroxyurea's antimetabolite properties and UV radiation exposure. Accordingly, we suggest that dermatomyositis-like eruption, previously considered a benign entity, may represent a premalignant precursor of hydroxyurea-associated nonmelanoma skin cancers warranting discontinuation of hydroxyurea therapy. (Source: Archives of Dermatology)
Second Malignant Neoplasm Occurring Years After Hyperthermic Isolated Limb Perfusion for Melanoma [Observation]
Conclusions&nbsp; Because long-term survivors of regionally advanced melanoma, although rare, do exist, candidates for HILP should be warned of the risk of long-term development of nonmelanoma secondary cancers. The risk-benefit balance of high-dose local chemotherapy should be carefully evaluated in the light of these findings, especially in patients with early-stage melanoma or other non&ndash;life-threatening medical conditions. (Source: Archives of Dermatology)
The Role of Circumstances of Diagnosis and Access to Dermatological Care in Early Diagnosis of Cutaneous Melanoma: A Population-Based Study in France [Study]
Conclusion&nbsp; Easy access of patients to dermatologists, information campaigns targeting elderly people, and education of general practitioners are complementary approaches to improving early detection. (Source: Archives of Dermatology)
Economic Burden of Melanoma in the Elderly Population: Population-Based Analysis of the Surveillance, Epidemiology, and End Results (SEER)-Medicare Data [Study]
Conclusions&nbsp; Melanoma care presents a significant economic burden in the elderly population, particularly in late-stage disease. If effective, prevention and early detection efforts may reduce the economic burden. (Source: Archives of Dermatology)
Error in Total Population in: Identification of Specific Quality Improvement Opportunities for the Elderly Undergoing Gastrointestinal Surgery [Correction]
(Source: Archives of Surgery)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Get the very latest Swine Flu news via the MedWorm <b><a href="http://www.medworm.com/rss/search.php?qu=%2Bswine+%2B%28influenza+flu%29&t=Swine+Flu&f=infectiousdiseases&r=Any&o=d" target ="_self">Swine Flu RSS news feed</a></b> - updated hourly from thousands of authoritative health and news sources.</p></div>
Vital Signs: Study Links Soda Price Increases to Better Health
Research found that when the price of a two-liter bottle went up, people consumed less, which was associated with a drop in weight and a lower risk for pre-diabetes. (Source: NYT &gt; Health)
Association Between Ambulatory 24-Hour Blood Pressure Levels and Cognitive Performance: A Cross-Sectional Elderly Population-Based Study
Rejuvenation Research Feb 2010, Vol. 13, No. 1: 39-46. (Source: Rejuvenation Research)
Adding Fat-Lowering Drug No Help for Diabetic Hearts
Adding a drug that lowers blood fats known as triglycerides to cholesterol-fighting statins provided no additional protection from heart attack, stroke and death from heart disease in patients with Type 2 diabetes, according to data from a large study.Source: Reuters Health Related MedlinePlus Pages: Diabetes, Heart Diseases, Statins (Source: MedlinePlus Health News)
Ezetimibe Reduces Hepatic Fat in Obese Patients
In insulin-resistant subjects on a weight loss diet, ezetimibe (Zetia) reduces hepatic steatosis and inflammatory markers, Australian researchers report in the February 25th online issue of Diabetes Care. Reuters Health Information (Source: Medscape Diabetes Headlines)
Balance Improves in Elderly Patients After Total Knee Replacement
Elderly patients who undergo total knee replacement for osteoarthritis have significant improvements in dynamic balance, according to study findings presented Thursday at the American Academy of Orthopaedic Surgeons meeting in New Orleans. Reuters Health Information (Source: Medscape Orthopaedics Headlines)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Get the very latest Swine Flu news via the MedWorm <b><a href="http://www.medworm.com/rss/search.php?qu=%2Bswine+%2B%28influenza+flu%29&t=Swine+Flu&f=infectiousdiseases&r=Any&o=d" target ="_self">Swine Flu RSS news feed</a></b> - updated hourly from thousands of authoritative health and news sources.</p></div>
Exenatide Improves Postprandial Endothelial Function
The diabetes drug exenatide (Byetta) is known to lower glucose and is believed to lower lipid excursions after meals, but new research suggests that it may also improve endothelial function. Reuters Health Information (Source: Medscape Diabetes Headlines)
ACC: Saline, Bicarb Tie for Kidney Safety (CME/CE)
ATLANTA (MedPage Today) -- Sodium bicarbonate hydration appears no better than the old standard, saline, in preventing kidney damage from use of radiology contrast agents in at-risk diabetes patients, according to one of the first head-to-head comparison trials. (Source: MedPage Today Cardiovascular)
Deborah Moggach: My mother, the murderess
Deborah Moggach on how her mother was imprisoned for helping a sick and elderly friend to die (Source: Telegraph Health)
Alkermes shares pop on FDA's diabetes-drug response
Alkermes Inc. shares popped Monday on news that federal regulators responded positively to a new diabetes-drug application filed by the Waltham, Mass.-based biotechnology firm and its development partners, Amylin Pharmaceuticals Inc. and Eli Lilly and Co. (LLY) (Source: bizjournals.com Health Care:Biotechnology headlines)
Factors associated with probability of personal digital assistant-based dietary self-monitoring in those with type 2 diabetes
This study examined modifiable and nonmodifiable factors associated with technology-based self-monitoring. 123 participants with type 2 diabetes self-monitored diet using a personal digital assistant in a 6-month behavioral intervention. Multinomial logistic regression was used to examine probability of nonadherent and suboptimally adherent behavior relative to adherent behavior. Sociodemographic characteristics were not associated with probability of self-monitoring. Probability of adherence generally was greater in the weeks preceding no group session, and lower in the weeks following no group session or following skipped sessions. Non-modifiable factors suggested by the literature to be associated with poorer access to technology (lower income, older age, minority race, and lower ...<div id="medworm"><p><b><i>MedWorm Message:</i></b> Get the very latest Swine Flu news via the MedWorm <b><a href="http://www.medworm.com/rss/search.php?qu=%2Bswine+%2B%28influenza+flu%29&t=Swine+Flu&f=infectiousdiseases&r=Any&o=d" target ="_self">Swine Flu RSS news feed</a></b> - updated hourly from thousands of authoritative health and news sources.</p></div>
Craniovertebral junction tuberculosis: a case report and review of the literature
We report on a 80-year-old woman presenting with CVJ TB without pulmonary involvement. The diagnosis was made by biopsy of the cervical lymph node showing granulomatous caseation necrosis. Despite extensive erosion of the clivus, C1, and C2, and spinal cord compression, the patient was effectively managed with antituberculous drug therapy and conservative neck stabilization. Neck pain resulting from cervical spondylosis is common in elderly people. However, even if there is no obvious pulmonary involvement, CVJ TB should be considered in the differential diagnosis, especially in patients with painful neck stiffness. The most useful method available for evaluating this region is a combination of CT scan and MRI study. CVJ TB can be managed conservatively, except for a selected few cas...
Possible cause of failure after McCall culdoplasty
Conclusion&nbsp;&nbsp;Failure of McCall culdoplasty occurs more frequently in patients with history of vaginal delivery of macrosomic infants, possibly due to direct pelvic floor damage. This technique should not be used in patients with a possible history of direct pelvic floor damage. Content Type Journal ArticleCategory General GynecologyDOI 10.1007/s00404-010-1418-0Authors Cetin Cam, Zeynep Kamil Hospital Department of Obstetrics and Gynecology No: 1, Selimiye, Uskudar 34668 Istanbul TurkeyAtes Karateke, Zeynep Kamil Hospital Department of Obstetrics and Gynecology No: 1, Selimiye, Uskudar 34668 Istanbul TurkeyMehmet Resit Asoglu, Zeynep Kamil Hospital Department of Obstetrics and Gynecology No: 1, Selimiye, Uskudar 34668 Istanbul TurkeySelcuk Selcuk, Zeynep Kamil Hospital...
Publix launches new diabetes program
Publix Pharmacies launched the first phase of a new diabetes management system March 15, which offers diabetic patients free medication. (Source: bizjournals.com Health Care:Biotechnology headlines)
NGM closes 1st tranche of $51M round
NGM Biopharmaceuticals closed the first tranche of a $51 million Series B financing, with plans to funnel the cash into diabetes treatments. (Source: bizjournals.com Health Care:Biotechnology headlines)
Julia's Spices Inc Recalls Hulled Sesame Seeds Because of Possible Health Risk
JULIA'S SPICES INC, of City of Industry, Ca is recalling all HULLED SESAME SEEDS distributed between November 17, 2009 and February 25,2010, because they have the potential to be contaminated with Salmonella, an organism which can cause serious and sometimes fatal infections in young children, frail or elderly people, and others with weakened immune systems. Healthy persons infected with Salmonella often experience fever, diarrhea (which may be bloody), nausea, vomiting and abdominal pain. (Source: Food and Drug Administration)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Get the very latest Swine Flu news via the MedWorm <b><a href="http://www.medworm.com/rss/search.php?qu=%2Bswine+%2B%28influenza+flu%29&t=Swine+Flu&f=infectiousdiseases&r=Any&o=d" target ="_self">Swine Flu RSS news feed</a></b> - updated hourly from thousands of authoritative health and news sources.</p></div>
Spice Industrial Inc. Recalls Lian How White Sesame Seeds Because of Possible Health Risk
SPICE INDUSTRIAL GROUP INC., of City of Industry, Ca is recalling LIAN HOW WHITE SESAME SEEDS supplied by Specialty Commodities Corp. distributed from November 6 to December 11, 2009, because they have the potential to be contaminated with Salmonella, an organism which can cause serious and sometimes fatal infections in young children, frail or elderly people, and others with weakened immune systems. Healthy persons infected with Salmonella often experience fever, diarrhea (which may be bloody), nausea, vomiting and abdominal pain. (Source: Food and Drug Administration)
ACCORD lipid: Fibrates do not improve CV outcomes in diabetic patients taking statins
Combination therapy with fenofibrate and simvastatin does not provide additional protection against cardiovascular disease in high-risk patients with Type 2 diabetes compared with simvastatin alone, according to findings from the ACCORD lipid trial. (Source: MedWire News - Lipidology)
Novel therapeutic concepts * The epidemic of cardiovascular disease in the developing world: global implications
The epidemic of cardiovascular disease (CVD) is a global phenomenon, and the magnitude of its increase in incidence and prevalence in low- and middle-income countries (LIMIC) has potentially major implications for those high-income countries that characterize much of the developed world. Cardiovascular disease remains the leading cause of death in the world and approximately 80% of all cardiovascular-related deaths occur in LIMIC and at a younger age in comparison to high-income countries. The economic impact in regard to loss of productive years of life and the need to divert scarce resources to tertiary care is substantial. The &lsquo;epidemiologic transition&rsquo; provides a useful framework for understanding changes in the patterns of disease as a result of societal and socioeconomic ...
Coronary sinus dilatation in an elderly patient with dyspnoea
(Source: European Heart Journal)
Comparison of health-related measures of two groups of adolescents in a rural southeastern county in the United States
Conclusion Thus, this research shows differences between similar populations in the same county and these differences must be explored further. (Source: Health Education Journal)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Get the very latest Swine Flu news via the MedWorm <b><a href="http://www.medworm.com/rss/search.php?qu=%2Bswine+%2B%28influenza+flu%29&t=Swine+Flu&f=infectiousdiseases&r=Any&o=d" target ="_self">Swine Flu RSS news feed</a></b> - updated hourly from thousands of authoritative health and news sources.</p></div>
Behavioural change in type 1 diabetes self-management: Why and how?
Conclusions Individuals intensively self-managing their diabetes have a high degree of motivation to improve glycaemic control, but also require the assistance of health professionals in primary and secondary care to enable this to take place. (Source: Health Education Journal)
Body's anticipation of a meal can be a diabetes risk factor
Alterations in our response to the taste or smell of food may be another culprit responsible for Type 2 diabetes, according to scientists who have identified the specific mechanism in human specimens and in mice. (Source: ScienceDaily Headlines)
Microscopic Colitis--A Common Cause of Diarrhoea in Older Adults
This article reviews the epidemiology, treatment, and management of microscopic colitis. Age and Ageing (Source: Medscape Rheumatology Headlines)
Search for Better Diabetes Therapy Falls Short
New strategies to prevent and treat diabetes and heart disease failed to improve care in two major studies, frustrating researchers' efforts to find more-effective approaches to the world's burgeoning diabetes epidemic. (Source: RWJF News Digest - Quality/Equality)
Senior drivers need more options: MDs
The rights of elderly drivers who may need their licences for safety reasons shouldn't win out over public safety, say doctors who argue for better transport programs. (Source: CBC | Health)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Get the very latest Swine Flu news via the MedWorm <b><a href="http://www.medworm.com/rss/search.php?qu=%2Bswine+%2B%28influenza+flu%29&t=Swine+Flu&f=infectiousdiseases&r=Any&o=d" target ="_self">Swine Flu RSS news feed</a></b> - updated hourly from thousands of authoritative health and news sources.</p></div>
Rhythm Pharma launches, raises $21M
Rhythm Pharmaceuticals Inc., a developer of peptide-based drugs to treat conditions such as obesity and diabetes, has launched with a $21 million Series A round of funding. The round was led by Boston?s MPM Capital and New Enterprise Associates of Maryland. (Source: bizjournals.com Health Care:Biotechnology headlines)
Landmark Accord Trial Finds Intensive Blood Pressure and Combination Lipid Therapies do not Reduce Combined Cardiovascular Events in Adults with Diabetes
BETHESDA, Md.,&nbsp;March 15, 2010--&nbsp;Lowering blood pressure to normal levels - below currently recommended levels - did not significantly reduce the combined risk of fatal or nonfatal cardiovascular disease events in adults with type 2... (Source: Drugs.com - Clinical Trials)
FDA letter moves Amylin drug toward approval
Amylin Pharmaceuticals, and partners Eli Lilly & Co. and Alkermes Inc., said Monday that their exenatide diabetes treatment is moving closer to approval by the Food and Drug Administration. (AMLN) (LLY) (Source: bizjournals.com Health Care:Biotechnology headlines)
Occurrence and Predictors of Futile Recanalization following Endovascular Treatment among Patients with Acute Ischemic Stroke: A Multicenter Study [INTERVENTIONAL]
CONCLUSIONS: Futile recanalization is a relatively common occurrence following endovascular treatment, particularly among elderly patients and those with severe neurologic deficits. (Source: American Journal of Neuroradiology)

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