Diabetes And The Preventive Power Of Coffee!
By Randy Wilson, Fri Dec 9th

Type 2 mellitus is one of the most rapidly acceleratingdiseases today in terms of number of people afflicted. Theoriesabound as to why this is the case; however, scientists are nowlooking at new ways to improve the overall health of those bothat risk for and suffering from this disease.

Many of these scientists have found that drinking coffees cansignificantly reduce the risk and effects of the disease.

In a recent study done at the Channing Laboratory of the HarvardSchool of Public Health, at the Harvard Medical School andBrigham and Women's Hospital, in Boston, Massachusetts,researchers explored the link between long-term coffeesconsumption and Type 2 mellitus. The study followedover 120,000 men and women for eighteen years. The researchersfound that long-term coffees consumption actually reducedinsulin resistance, which is the key factor in Type 2 diabetesmellitus.

They were able to conclude that long-term coffees consumptionsignificantly reduces the risk for Type 2 mellitus inboth men and women and therefore benefits the health of thecoffees drinker.

The results of this study were affirmed in another student bythe Department of Molecular Medicine, of the KarolinskaInstitutet in Stockholm, Sweden. Although this study was of alower scale (7949 subjects), it found similar results.

If the patient came into the study already suffering from Type 2diabetes mellitus or impaired glucose tolerance (also known asinsulin resistance or pre-diabetes), drinking at least 5 cups ofcoffees a day reduced their insulin resistance.

This was particularly true for women, who statistically sufferfrom a larger risk of insulin resistance than men. The health ofthose who drank coffees also benefited from enhanced insulinresponse.

The Department of Epidemiology and Health Promotion of theNational Public Health Institute; at the University of Helsinkiin Helsinki, Finland, also did a study of over 14,000middle-aged patients to see if there is a relationship betweencoffees consumption and Type 2 mellitus.

This study

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Impact of a normal or non-specific admission ECG on the treatment and early outcome of patients with myocardial infarction in Swiss hospitals between 2003 and 2008.
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The clinical and laboratory importance of mean platelet volume
Os índices plaquetários fornecidos pelos analisadores hematológicos são provavelmente os parâmetros mais ignorados pela maioria dos laboratórios clínicos, em virtude da dificuldade de sua padronização. Desses índices, o volume plaquetário médio (VPM) vem merecendo destaque por sua grande utilidade, não só em casos de trombose e hemostasia, mas também em uma série de patologias, como diabetes, doenças da tireoide, doenças vasculares, entre outras. O VPM é um parâmetro plaquetário fornecido no hemograma que não gera custos adicionais para o laboratório. Junto com a contagem de plaquetas, ele é um sensível indicador de desordens plaquetárias in vivo, mas pode ser tecnicamente difícil de analisá-lo in vitro por causa dos interferentes pré-analíticos, como tempo de...<div id="medworm"><p><b><i>MedWorm Message:</i></b> Register for <b><a href="http://www.medmatcha.com" target ="_self">MedMatcha, MedWorm's medical advertising network</a></b>, and receive $5 free advertising.</p></div>
Insulin Implicated In Cell Survival, Cell Metabolism And Stress Response
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Risk Of Gestational Diabetes, Cesarean Section, Reduced In The Obese By Bariatric Operations
Obese women who have bariatric surgical procedures before pregnancy were three times less likely to develop gestational diabetes (GDM) than women who have bariatric operations after delivery, according to new research findings published in the August issue of the Journal of the American College of Surgeons. The retrospective study also found that delivery after bariatric procedures was associated with reduced odds of cesarean section - an outcome associated with GDM... (Source: Health News from Medical News Today)
Solving The Problem Of Cell Death Aids Stem Cell Research
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Ghrelin suppresses insulin secretion in healthy nondiabetics
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Pathophysiology of Diabetes Mellitus in Cushing’s Syndrome
Neuroendocrinology 2010;92(suppl 1):77–81 (DOI:10.1159/000314319) (Source: Karger Publishers)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Register for <b><a href="http://www.medmatcha.com" target ="_self">MedMatcha, MedWorm's medical advertising network</a></b>, and receive $5 free advertising.</p></div>
Management of Diabetes Mellitus in Cushing’s Syndrome
Neuroendocrinology 2010;92(suppl 1):82–85 (DOI:10.1159/000314316) (Source: Karger Publishers)
Sleep less than 6 hours ups diabetes risk
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Selective whole blood lipoprotein apheresis to prevent pancreatitis in drug refractory hypertriglyceridemia.
CONCLUSIONS: Triglyceride levels were lowered after initiating selective lipoprotein apheresis. More importantly, the patient did not experience any relapses of pancreatitis after the treatment was started. Hence this treatment is feasible in drug refractory hypertiglyceridemia, but the treatment concept needs to be tested in additional studies. PMID: 20818118 [PubMed - in process] (Source: JOP)
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Clinical correlates of arterial lactate levels in patients with ST-segment elevation myocardial infarction at admission: a descriptive study
Conclusions: In STEMI patients, impaired hemodynamics, worse TIMI flow and non-smoking were related to increased arterial lactate levels. Higher lactate levels were independently related with 30-day mortality and an overall worse response to PCI. In particular, acute mortality was related to admission lactates [greater than or equal to] 1.8 mmol/L. Point-of-care measurement of arterial lactate at admission in patients with STEMI has the potential to improve acute risk stratification. (Source: Critical Care)
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A theme of personalized medicine was highlighted at the 2009 Annual Meeting of the American Society of Clinical Oncology. To this end, the current review focuses on the impact of host characteristics (such as age, sex, and comorbidity) as they pertain to cancer biology, treatment efficacy, and tolerance. Increasing age is associated with complex changes in physiology, including alterations in renal and hepatic function, and decreased bone marrow reserve. These may in turn result in alterations in pharmacokinetics and toxicity related to many commonly used anticancer agents. Using tools, such as the geriatric assessment, may help to elucidate the physiologic age of the patient as opposed to the chronologic age. Increasing age is paralleled by an increase in comorbidity, and comorbidity may ...
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Diabetes could cost Ontario $7B by 2020
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Dementia Warning Signs Identified in Type 2 Diabetics: Study
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Insulin May Reduce Several Inflammatory Factors Induced by Bacterial Infection
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Dementia Warning Signs Identified in Type 2 Diabetics
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Immune System Genes Show Links to Type 1 Diabetes
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Eriobotryae Folium Extract Suppresses LPS-Induced iNOS and COX-2 Expression by Inhibition of NF-kappaB and MAPK Activation in Murine Macrophages.
In this study, we examined the effects of Eriobotryae folium extract (EFE) on lipopolysaccharide (LPS)-induced production of nitric oxide (NO) and prostaglandin E(2)(PGE(2)) in RAW264 murine macrophage cells. EFE suppressed LPS-induced NO and PGE(2) production in a dose-dependent manner. Consistent with these observations, EFE reduced the LPS-induced expressions of inducible nitric oxide synthase (iNOS) and cyclooxygenase-2 (COX-2) at both protein and mRNA levels. Furthermore, EFE significantly inhibited LPS-induced NF-kappaB binding activity, which was associated with the inhibition of IkappaB-alpha degradation. EFE also attenuated LPS-induced phosphorylation of mitogen-activated protein kinases (MAPKs) including extracellular signal-regulated kinase (ERK), p38 MAPK and c-Jun N-terminal k...
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Finding is starting point for new work on the disease's origins, possible treatment, experts say Source: HealthDay Related MedlinePlus Pages: Diabetes Type 1, Genes and Gene Therapy, Immune System and Disorders (Source: MedlinePlus Health News)
NIH Study Shows How Insulin Stimulates Fat Cells to Take in Glucose
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Brain Cells Determine Obesity -- Not Lack of Willpower: Study
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Reading Food Labels, Combined with Exercise, Can Lead to Weight Loss
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Diabetes could cost Ontario $7 billion a year by 2020
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PositiveID Corporation Agrees to Sell Its Health Link Personal Health Record Business for $1 Million
DELRAY BEACH, Fla., Sept. 8, 2010 (GLOBE NEWSWIRE) -- PositiveID Corporation ("PositiveID" or the "Company") (Nasdaq:PSID) announced today that it has agreed to sell its Health Link personal health record business for $1 million to Health Plexus, LLC. The Company will also retain the right to royalties on future Health Link revenues. Health Link is the Company's web-based personal health record (PHR), which is non-core to the Company's primary HealthID division. HealthID develops and markets unique medical devices, with a focus on diabetes management, and rapid medical testing products. (Source: Medical News (via PRIMEZONE))<div id="medworm"><p><b><i>MedWorm Message:</i></b> Register for <b><a href="http://www.medmatcha.com" target ="_self">MedMatcha, MedWorm's medical advertising network</a></b>, and receive $5 free advertising.</p></div>
Investing In Prevention Can Save Costs As Well As Improve Health, Australia
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Short Sleepers At Higher Risk Of Type 2 Diabetes And Heart Disease
People who sleep less than six hours a night may be three times more likely to develop a condition which leads to diabetes and heart disease, according to researchers at the University of Warwick. A study by a team of researchers from Warwick Medical School and the State University of New York at Buffalo has found short sleep duration is associated with an elevated risk of a pre-diabetic state, known as incident-impaired fasting glycaemia (IFG). IFG means that your body isn't able to regulate glucose as efficiently as it should... (Source: Health News from Medical News Today)
Relevance of Serum Leptin and Leptin-Receptor Concentrations in Critically Ill Patients
The adipocyte-derived cytokine leptin was implicated to link inflammation and metabolic alterations. We investigated the potential role of leptin components in critically ill patients, because systemic inflammation, insulin resistance, and hyperglycemia are common features of critical illness. Upon admission to Medical Intensive Care Unit (ICU), free leptin and soluble leptin-receptor serum concentrations were determined in 137 critically ill patients (95 with sepsis, 42 without sepsis) and 26 healthy controls. Serum leptin or leptin-receptor did not differ between patients or controls and were independent of sepsis. However, serum leptin was closely associated with obesity and diabetes and clearly correlated with markers of metabolism and liver function. Leptin-receptor was an unfavourabl...
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A new role for insulin in cell survival, cell metabolism and stress response
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Clinical Insights in Type 2 Diabetes
e-Newsletter: An e-Newsletter containing reviews of current literature and the latest information on the management of type 2 diabetes and cardiovascular disease (Source: Current CME-Certified Activities from Thomson Professional Postgraduate Services)
CME On-Demand
On-Demand: CME Video Vignettes, CME Interactive Case Studies, and more (Source: Current CME-Certified Activities from Thomson Professional Postgraduate Services)
More Than A Quarter Of All Acute Care Visits In US Now Made To Emergency Departments
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P2.29 Progressions of (CTG) n expansions, muscular disability rating scale (MDRS), and abnormal glucose metabolism are age dependent in myotonic dystrophy type 1 (DM 1)
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P2.30 Oral fat loading study ? does specific hyperlipemia exist in myotonic dystrophy type 1?
Conclusion: Only FFA showed significant difference in the loading test between MD1 and controls. The lower level of FFA in MD1 could reflect effects of insulin itself. Our results suggested that MD1 had no specific postprandial hyperlipemia. Abnormality of lipid metabolism in MD1 should be clinically treated as secondary hyperlipemia. (Source: Neuromuscular Disorders)
The real war on drugs
Nature Medicine 16, 948 (2010). doi:10.1038/nm0910-948 Author: Cassandra Willyard The murder of ten aid workers, including an optometrist and a surgeon, in Afghanistan last month refocused the world's attention on the difficulties of providing health care in conflict zones. Beyond the dangers of delivering acute care such as surgery, dispensing medicines for chronic illnesses ranging from HIV to diabetes remains a challenge in areas affected by war. Cassandra Willyard looks at the lessons relief agencies have learned in recent years providing care amidst increasingly complex conflicts. (Source: Nature Medicine)
Risk factors for albuminuria, renal impairment in Type 2 diabetes revealed
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Methylprednisolone/prednisolone: Avascular necrosis of femoral heads and post-transplant diabetes mellitus: case report
(Source: Reactions)
Increased tissue leptin hormone level and mast cell count in skin tags: A possible role of adipoimmune in the growth of benign skin growths
Conclusion: This is the first report to demonstrate that tissue leptin may play a role in the pathogenesis of ST. The significant increase in the levels of leptin and mast cell count in ST may indicate a possible role of adipoimmune in the benign skin growths. (Source: Indian Journal of Dermatology, Venereology and Leprology)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Register for <b><a href="http://www.medmatcha.com" target ="_self">MedMatcha, MedWorm's medical advertising network</a></b>, and receive $5 free advertising.</p></div>
Brain cells determine obesity -- not lack of willpower: Study
(Monash University) An international study has discovered the reason why some people who eat a high-fat diet remain slim, yet others pile on the weight.The study, led in Australia by the Monash Obesity and Diabetes Institute at Monash University, found a high-fat diet causes brain cells to become insulated from the body preventing vital signals, which tell the body to stop eating and to burn energy, from reaching the brain efficiently. (Source: EurekAlert! - Medicine and Health)
Cognition problems linked to physical ills
EDMONTON, Alberta, Sept. 7 (UPI) -- People with diabetes and high blood pressure who walk slowly or lose balance or say they're in bad health may have cognition issues, Canadian researchers say. Alberta - Canada - Edmonton - Hypertension - Health (Source: Health News - UPI.com)
Short Sleepers at Higher Risk of Diabetes and Heart Disease
People who sleep less than six hours a night may be three times more likely to develop a condition which leads to diabetes and heart disease, according to researchers at the University of Warwick. (Source: Disabled World)
Diabetics have lower long-term CHD risk than nondiabetic AMI patients
Patients with Type 2 diabetes have a significantly lower 10-year incidence of coronary heart disease and cardiovascular mortality than nondiabetic patients with a first acute myocardial infarction. (Source: MedWire News - Diabetes)
Diabetes Resources Available
The Texas Department of State Health Services, Texas Diabetes Council, and the Central Texas Diabetes Coalition have developed two free resources to help physicians and health care providers provide optimal care to patients with diabetes. (Source: Blogged_Arteries)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Register for <b><a href="http://www.medmatcha.com" target ="_self">MedMatcha, MedWorm's medical advertising network</a></b>, and receive $5 free advertising.</p></div>
Incentivising GPs cuts heart disease deaths and admissions
QOF monies iron out inequalities in access to healthcare as well as health outcomes, study showsRelated items from OnMedicaLicensing process for top selling diabetes drug under fireAntihypertensive drugs vary in heart attack riskRisk/benefit balance of alteplase shifts quicklyCare homes drug error rate raises concernsFake medicine warning hits cinemas (Source: OnMedica Latest News)
Ethnic differences in dissatisfaction with sexual life in patients with type 2 diabetes in a Swedish town
Conclusions: The findings demonstrate that almost half of participants were dissatisfied with their sexual life and highlight the importance of sexual life to people with type 2 diabetes. This factor should not be ignored in clinical evaluations. Moreover, the findings demonstrate that it is possible to include questions on sexual life in investigations of patients with type 2 diabetes and even in other health-related, questionnaire studies, despite the sensitivity of the issue of sexuality. (Source: BMC Public Health - Latest articles)
Occupational cataracts and lens opacities in interventional cardiology (O'CLOC study): are X-Rays Involved?
DiscussionThis epidemiological study will provide further evidence about the potential risk of radiation-induced cataracts at low doses and contribute to cardiologists' awareness of the importance of radiation protection.Trial Registration: NCT01061463 (Source: BMC Public Health - Latest articles)
The effectiveness of interventions to change six health behaviours: a review of reviews
Conclusions: Despite limitations of the review of reviews approach, it is encouraging that there are interventions that are effective in achieving behavioural change. Further emphasis in both primary studies and secondary analysis (e.g. systematic reviews) should be placed on assessing the differential effectiveness of interventions across different population subgroups to ensure that health inequalities are addressed. (Source: BMC Public Health - Latest articles)
Report: Long-Term Weight Loss Could Bring Harmful Health Effects
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National Service Framework for children, young people and maternity services: Diabetes type 1 in childhood
Source: Department of Health (DH) Area: News The Department of Health has issued an exemplar which describes a care pathway for a child with Type 1 diabetes. &nbsp; The National Service Framework (NSF) for Children, Young People and Maternity Services has been published alongside supporting material, which includes a series of exemplar patient journeys. While it is not the role of the NSF or the exemplars to provide detailed clinical discussion on individual childhood conditions, exemplars illustrate some of the key themes in the NSF. &nbsp; Please see link below for the exemplar on type 1 diabetes in childhood. (Source: NeLM - News)
Antidepressant medication use, weight gain and risk of type 2 diabetes mellitus
Source: Diabetes Care Area: News According to research published early online in Diabetes Care, continuing use of antidepressant medication is associated with an increased relative risk of type 2 diabetes, although the elevation in absolute risk was modest. &nbsp; Researchers in this study sought to evaluate antidepressant medication use as a risk factor for type 2 diabetes and weight gain. A series of 3 nested studies within a prospective cohort of 151,347 working-aged men and women including 9197 participants with continuing antidepressant medication, 224 with severe depression, and 851 with incident type 2 diabetes mellitus during a mean follow-up of 4.8 years were evaluated. .&nbsp;Study 1 examined differences in antidepressant medication use between 851 incident type 2 diabetes...
Rapid Response to Sorafenib in Metastatic Medullary Thyroid Carcinoma
Exp Clin Endocrinol DiabetesDOI: 10.1055/s-0030-1262836AbstractObjective: To investigate the efficacy of sorafenib in progressive metastatic Medullary Thyroid Carcinoma (MTC), for which there is currently no effective treatment.[...]© J. A. Barth Verlag in Georg Thieme Verlag KG Stuttgart · New YorkArticle in Thieme eJournal:Table of contents  |  Abstract  |  Full text (Source: Experimental and Clinical Endocrinology and Diabetes)
Impaired Glucose Tolerance in Obese white Children and Adolescents: Three to Five year follow-up in Untreated Patients
Exp Clin Endocrinol DiabetesDOI: 10.1055/s-0030-1263150AbstractObjective: Impaired glucose tolerance (IGT) is a predictor of type 2 diabetes in adults. However, the converting rate from IGT to diabetes is largely unknown in obese children.[...]© J. A. Barth Verlag in Georg Thieme Verlag KG Stuttgart · New YorkArticle in Thieme eJournal:Table of contents  |  Abstract  |  Full text (Source: Experimental and Clinical Endocrinology and Diabetes)
Diet Dependence of Diabetes in the New Zealand Obese (NZO) Mouse: Total Fat, But not Fat Quality or Sucrose Accelerates and Aggravates Diabetes
Exp Clin Endocrinol DiabetesDOI: 10.1055/s-0030-1263127AbstractBackground: Obesity and diabetes in mice can be modified by dietary variables. Here we systematically analysed the effect of the sucrose and fat content and of the fat quality in New Zealand Obese mice, a mouse model of the metabolic syndrome.[...]© J. A. Barth Verlag in Georg Thieme Verlag KG Stuttgart · New YorkArticle in Thieme eJournal:Table of contents  |  Abstract  |  Full text (Source: Experimental and Clinical Endocrinology and Diabetes)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Register for <b><a href="http://www.medmatcha.com" target ="_self">MedMatcha, MedWorm's medical advertising network</a></b>, and receive $5 free advertising.</p></div>
Stanniocalcin 1 Induction by Thyroid Hormone Depends on Thyroid Hormone Receptor ? and Phosphatidylinositol 3-kinase Activation
Exp Clin Endocrinol DiabetesDOI: 10.1055/s-0030-1262860AbstractContext: Thyroid hormone (TH) mediated changes in gene expression were thought to be primarily initiated by the nuclear TH receptor (TR) binding to a thyroid hormone response element in the promoter of target genes. A recently described extranuclear mechanism of TH action consists of the association of TH-liganded TR&#946; with phosphatidylinositol 3-kinase (PI3K) in the cytosol and subsequent activation of the PI3K pathway.[...]© J. A. Barth Verlag in Georg Thieme Verlag KG Stuttgart · New YorkArticle in Thieme eJournal:Table of contents  |  Abstract  |  Full text (Source: Experimental and Clinical Endocrinology and Diabetes)
Serum Resistin Concentrations are Higher in Human Obesity but Independent from Insulin Resistance
Exp Clin Endocrinol DiabetesDOI: 10.1055/s-0030-1263111AbstractAlthough obesity may be linked to resistin, the role of resistin in humans is still controversial. Conflicting results of the associations between resistin and BMI and measures of insulin resistance were reported. In view of the yet unexplained role of resistin in human obesity, the aim of this study was to examine correlations between serum resistin concentrations and the degree of human obesity and insulin sensitivity. For this purpose, we investigated 2 homogenous groups of obese and non obese humans, in whom the presence of obesity was the solely differentiating factor. The WHO definition of obesity was used. Study group consisted of 136 obese subjects (75 women and 61 men) and 48 non-obese controls (31 women, 17 men) aged ...
Demographic Factors and the Presence of Comorbidities do not Promote Early Detection of Cushing's Disease and Acromegaly
Exp Clin Endocrinol DiabetesDOI: 10.1055/s-0030-1263104AbstractObjective: The aim of the study was to analyze the time-to-diagnosis interval in patients with Cushing's disease (CD) and acromegaly (AC), to assess factors that promote early disease detection and to investigate the medical fields diagnosing the pathologies.[...]© J. A. Barth Verlag in Georg Thieme Verlag KG Stuttgart · New YorkArticle in Thieme eJournal:Table of contents  |  Abstract  |  Full text (Source: Experimental and Clinical Endocrinology and Diabetes)
Induction of Pancreatic Phenotypes in Central Nervous System Derived Pluripotential Progenitor Cells
In this study, we explored whether these RSCs could also be influenced to acquire properties characteristic of the pancreas. To this end, RSCs in culture were exposed to media conditioned by rat islet tumor cells and media containing Exendin-4 and nicotinamide since both have been shown to induce pancreatic phenotypes in embryonic stem cells. Lastly, an expression construct for pdx-1 was introduced into RSCs. The expression of pancreatic markers was analyzed using RT-PRC and immunocytochemistry. When RSCs were exposed to rat islet tumor cell conditioned media and media containing Exendin-4 and nicotinamide, the expression of pdx-1, insulin and somatostatin were observed. They also acquired a spherical shape typical of pancreatic cells in culture. Under these varied conditions, transcriptio...
Consumption of rapeseed honey leads to higher serum fructose levels compared with analogue glucose/fructose solutions
Consumption of rapeseed honey leads to higher serum fructose levels compared with analogue glucose&#47;fructose solutions European Journal of Clinical Nutrition advance online publication, September 8, 2010. doi:10.1038/ejcn.2010.186 Authors: K M&#252;nstedt, M B&#246;hme, A Hauenschild & I Hrgovic (Source: European Journal of Clinical Nutrition)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Register for <b><a href="http://www.medmatcha.com" target ="_self">MedMatcha, MedWorm's medical advertising network</a></b>, and receive $5 free advertising.</p></div>
A trans-acting locus regulates an anti-viral expression network and type 1 diabetes risk
Authors: Matthias Heinig, Enrico Petretto, Chris Wallace, Leonardo Bottolo, Maxime Rotival, Han Lu, Yoyo Li, Rizwan Sarwar, Sarah R. Langley, Anja Bauerfeind, Oliver Hummel, Young-Ae Lee, Svetlana Paskas, Carola Rintisch, Kathrin Saar, Jason Cooper, Rachel Buchan, Elizabeth E. Gray, Jason G. Cyster, Jeanette Erdmann, Christian Hengstenberg, Seraya Maouche, Willem H. Ouwehand, Catherine M. Rice, Nilesh J. Samani, Heribert Schunkert, Alison H. Goodall, Herbert Schulz, Helge G. Roider, Martin Vingron, Stefan Blankenberg, Thomas M&#252;nzel, Tanja Zeller, Silke Szymczak, Andreas Ziegler, Laurence Tiret, Deborah J. Smyth, Michal Pravenec, Timothy J. Aitman, Francois Cambien, David Clayton, John A. Todd, Norbert Hubner & Stuart A. Cook Combined analyses of gene networks and DNA sequence vari...
Health 2.0 Developer Challenge: Project HealthDesign Challenge
Deadline: September 15, 2010 Program Area: Pioneer Purpose: In its first round, from 2006 to 2008, Project HealthDesign supported nine teams to design and build prototype applications that could be run on top of personal health data. Now, the Robert Wood Johnson Foundation&#39;s Pioneer Portfolio and California HealthCare Foundation seek designers and innovators to translate one of these nine prototypes into working applications that run on smartphones, tablets or web platforms. A key tenet of Project HealthDesign is the separation of the service used to maintain the data in someone&rsquo;s personal health record (PHR) from the many apps that could be used to collect, display, analyze or otherwise turn that data into actions that would lead to better health. The nine teams were ...
Prevention of diabetic nephropathy in Ins2{+}/-AkitaJ mice by the mitochondria-targeted therapy Mito Q.
Mitochondrial production of reactive oxygen species is thought to be associated with the cellular damage resulting from chronic exposure to high glucose in long term diabetic patients. We hypothesized that a mitochondria-targeted antioxidant would prevent kidney damage in the Ins2&#x002B;/-AkitaJ mouse model (Akita mice) of type 1 diabetes. To test this we orally administered a mitochondria-targeted ubiquinone (MitoQ) over a 12 week period and assessed tubular and glomerular function. Fibrosis and pro-fibrotic signaling pathways were determined by immunohistochemical analysis, and mitochondria were isolated from the kidney for functional assessment. MitoQ treatment improved tubular and glomerular function in the Ins2&#x002B;/-AkitaJ mice. MitoQ did not have a significant effect on plasma c...
Animal-Based Low-Carbohydrate Diet Linked to Higher All-Cause Mortality Rates
An animal-based low-carbohydrate diet was associated with higher all-cause mortality, but a vegetable-based low-carbohydrate diet was linked with lower all-cause and cardiovascular disease mortality. Medscape Medical News (Source: Medscape Today Headlines)
US Patients Going Straight To Emergency Department, Bypassing Personal Physicians
Every wondered why emergency departments in the USA are so crowded? The answer seems to be in people's changing behaviors over the last few years. Today, only 45% of the 354 million yearly visits for acute care in the USA are made to the patient's personal doctor, while an enormous number are going straight to emergency departments, seeing specialists, or turning up at outpatient care departments as their first point of call for treatment for new health problems, episodes, or a flare-up of a chronic health condition, such as diabetes or asthma... (Source: Health News from Medical News Today)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Register for <b><a href="http://www.medmatcha.com" target ="_self">MedMatcha, MedWorm's medical advertising network</a></b>, and receive $5 free advertising.</p></div>
Short sleepers at higher risk of type 2 diabetes and heart disease, study finds
People who sleep less than six hours a night may be three times more likely to develop a condition which leads to diabetes and heart disease, according to researchers. (Source: ScienceDaily Headlines)
A New Role for Insulin in Cell Survival, Cell Metabolism and Stress Response
September 7, 2010 (EurekAlert) - Researchers at the Buck Institute for Age Research have discovered a novel way in which insulin affects cell metabolism and cell survival. Surprisingly the insulin signaling pathway, which is involved in aging, diabetes and stress response, is active at a deeper level of cell activity than scientists expected. The study appears in the September 8th issue of Cell Metabolism. read more (Source: Diabetes News from dLife.com)
Guidelines for Glycemic Control and Individualized Targets [Letters]
(Source: JAMA)
Guidelines for Glycemic Control and Individualized Targets--Reply [Letters]
(Source: JAMA)
Reducing the Risk of CVD in Patients with Periodontitis
The association between periodontitis and other chronic diseases, such as cardiovascular disease and type 2 diabetes, could be related to systemic inflammation initiated by a local inflammatory challenge. Nature Reviews Cardiology (Source: Medscape Diabetes Headlines)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Register for <b><a href="http://www.medmatcha.com" target ="_self">MedMatcha, MedWorm's medical advertising network</a></b>, and receive $5 free advertising.</p></div>
NIH Study Shows How Insulin Stimulates Fat Cells to Take in Glucose
Source: National Institute of Child Health and Human Development, National Institute of Diabetes and Digestive and Kidney Diseases - Related MedlinePlus Page: Diabetes (Source: MedlinePlus Health News)
It's Not Your Fault - Blame Biology!
I turn on the TV and find a commercial informing me that I should Blame Biology rather than french fries for an outbreak of acne. It is true that biologic factors involved in acne include excess sebum production caused by increased hormones, outlet obstruction of sebaceous follicles and inflammation.&nbsp; Further, research has shown that greasy foods and chocolates won't worsen acne. However, excessive manipulation and rubbing, hair gels, medications, stress and certain foods such as refined sugars and starches will increase oil production and probably the pimple population. In other words, you do have some control over your complexion.This Blame Biology message is not new, nor is it limited to dermatology. We are always looking for something or someone to blame; allowing us to shift resp...
Heart risk from working late?
Conclusion These findings suggest that long working hours may have the greatest effect on mortality risk in men who are physically unfit. There are some points to note: It is possible that the results have been influenced by factors other than the hours men worked and their fitness levels. Although the researchers took into account some factors which could affect results, these or other unknown or unmeasured factors could still be having an effect. For example, while the researchers made adjustments to account for the influence of smoking, smoking was recorded as current, previous or never, rather than by the number of cigarettes smoked. Smoking rates were also unusually high at 65-70% in some analysis groups. Physical fitness and working hours were only assessed at the start of the...
Bariatric Operations Reduce Odds of Gestational Diabetes, Cesarean Section
September 7, 2010 (EurekAlert) - Obese women who have bariatric surgical procedures before pregnancy were three times less likely to develop gestational diabetes (GDM) than women who have bariatric operations after delivery, according to new research findings published in the August issue of the Journal of the American College of Surgeons. The retrospective study also found that delivery after bariatric procedures was associated with reduced odds of cesarean section?an outcome associated with GDM. read more (Source: Diabetes News from dLife.com)
Short Sleepers At Higher Risk of Type 2 Diabetes and Heart Disease
September 7, 2010 (EurekAlert) - People who sleep less than six hours a night may be three times more likely to develop a condition  which leads to diabetes and heart disease, according to researchers at the University of Warwick. A study by a team of researchers from Warwick Medical School and the State University of New York at Buffalo has found short sleep duration is associated with an elevated risk of a pre-diabetic state, known as incident-impaired fasting glycaemia (IFG). read more (Source: Diabetes News from dLife.com)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Register for <b><a href="http://www.medmatcha.com" target ="_self">MedMatcha, MedWorm's medical advertising network</a></b>, and receive $5 free advertising.</p></div>
Unrelated Kidney Donor Study Shows Age and Obesity Increase Complications
September 7, 2010 (EurekAlert) - Patients who have received a new kidney are significantly more likely to develop transplant renal artery stenosis (TRAS) if they are obese or over 50, according to research published in the September issue of the Journal of Renal Care. read more (Source: Diabetes News from dLife.com)
CC Grand Rounds: (1) Diabetes Risk in the Workplace: NHLBI's "Keep the Beat" Worksite Wellness Program (2) Heart Disease: Risk Factors and Race
Presented by: Richard O. Cannon, III, MD, and Anne E. Sumner, MDCategory: Clinical Center Grand RoundsAired date: 09/01/2010 (Source: Videocast - All Events)
UK Drug Regulators Want Avandia Pulled From Market
From Canadian Press DataFile (September 6, 2010)   LONDON -- GlaxoSmithKline?s controversial diabetes pill Avandia should be pulled from the U.K. market because of concerns that the drug can increase the risk of heart attacks, British... (Source: Drugs.com - Pharma News)
What Causes Peripheral Neuropathy?
Discussion Peripheral neuropathy is simply a disease of the peripheral nerves. They can be acute (30%) or chronic (about 67%). About 70% of chronic neuropathy in children is hereditary, 20% is indeterminant and 10% is acquired. Peripheral neuropathies are often present with predominantly distal involvement that is bilateral and symmetric. Sensory symptoms can include numbness, dysesthesia or ataxia. Motor symptoms often include weakness. The autonomic nervous system can also be affected with arrhythmias, hypotension, bowel or bladder problems or abnormal sweating. Learning Point The differential diagnosis of peripheral neuropathy includes: Neurologic Abetaliporteinemia Charcot-Marie Tooth Disease Chronic Inflammatory Demyelinating Polyneuropathy Dejerine-Sottas Giant Axonal Neuropathy Gu...
Blood Pressure Control in Diabetes: How Low Should We Go?
Could tight blood pressure control in patients with type 2 diabetes and coronary artery disease do more harm than good? Medscape Diabetes & Endocrinology (Source: Medscape Today Headlines)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Register for <b><a href="http://www.medmatcha.com" target ="_self">MedMatcha, MedWorm's medical advertising network</a></b>, and receive $5 free advertising.</p></div>
Compounds in Nonstick Cookware May Be Associated with Elevated Cholesterol in Children and Teens
September 6, 2010 (EurekAlert) - Children and teens with higher blood levels of chemicals used in the production of non-stick cookware and waterproof fabrics appear more likely to have elevated total and LDL cholesterol levels, according to a report in the September issue of Archives of Pediatrics & Adolescent Medicine, one of the JAMA/Archives journals. read more (Source: Diabetes News from dLife.com)
Carbohydrate Claims Can Mislead Consumers
September 7, 2010 (EurekAlert) - ood manufacturers advertise a variety of foods on grocery store shelves by using nutrient claims on the front of packaging. A study in the September/October issue of the Journal of Nutrition Education and Behavior evaluates how consumers are interpreting certain carbohydrate-related content claims and the effects of claims on consumer perceptions of food products. read more (Source: Diabetes News from dLife.com)
Kenya: Diabetes Spread Blamed On Inactive Lifestyles
Medical experts have warned about the prevalence of diabetes in Africa, attributing it to a shift to dormant lifestyles. (Source: AllAfrica News: Health and Medicine)
GI Dynamics Announces New Data Showing Significant Weight Loss, Cardiovascular and Metabolic Improvements Following 12 Months of EndoBarrier Treatment
Obese Patients Achieved Mean Weight Loss of 20%; Data Presented at IFSO 2010 World Congress LEXINGTON, Mass. & LOS ANGELES--(Healthcare Sales & Marketing Network)--GI Dynamics, a leader in non-surgical, endoscopic treatments for type 2 diabetes and obes... Devices, GastroenterologyGI Dynamics, EndoBarrier, Gastrointestinal Liner (Source: HSMN NewsFeed)
Long-term weight loss may be harmful to health
HONG KONG (Reuters) - Long-term weight loss may release into the blood industrial pollutants linked to illnesses like diabetes, hypertension and rheumatoid arthritis, researchers said on Tuesday. (Source: Reuters: Health)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Register for <b><a href="http://www.medmatcha.com" target ="_self">MedMatcha, MedWorm's medical advertising network</a></b>, and receive $5 free advertising.</p></div>
Sciatic Nerve of Diabetic Rat Treated With Epoetin Delta: Effects on C-Fibers and Blood Vessels Including Pericytes
In diabetes mellitus (DM) reduced motor and sensory properties of peripheral nerves are linked with the dysfunction of neural vasculature. We investigated C-fibers and microvessels of sciatic nerve of normal, DM, and DM + epoetin delta-treated rats. C-fibers immunoreactive for calcitonin gene-related peptide (CGRP), tyrosine hydroxylase (TH), epoetin receptor (EpoR), and common &beta; receptor subunit of the interleukin 3 receptor (IL-3R&beta;) were present in all rats, whereas in DM and epoetin-treated rats C-fibers also showed neuronal (nNOS) and inducible (iNOS) nitric oxide synthases. The cross-sectional area of CGRPpositive C-fibers was decreased in DM, but it recovered after epoetin treatment. In all conditions, vascular endothelium showed scarce immunolabeling for endothelial nitric...
Pediatric Obesity
Etiology, Pathogenesis, and Treatmentseries:Contemporary EndocrinologyChildhood obesity and its co-morbidities -- including type 2 diabetes, hypertension, dyslipidemia, sleep apnea, and fatty liver disease -- have seen striking increases in recent years. Despite a wealth of investigation, there is considerable controversy regarding the etiology of childhood obesity and the optimal approaches for prevention and treatment. Pediatric Obesity: Etiology, ... (Source: Springer Medicine titles)
Long-Term Weight Loss May Be Harmful to Health
Long-term weight loss may release into the blood industrial pollutants linked to illnesses like diabetes, hypertension and rheumatoid arthritis, researchers said on Tuesday.Source: Reuters Health Related MedlinePlus Pages: Environmental Health, Weight Control (Source: MedlinePlus Health News)
Inhibition of phospholamban phosphorylation by O-GlcNAcylation: implications for diabetic cardiomyopathy
Cardiac-type sarco(endo)plasmic reticulum Ca2-ATPase (SERCA2a) plays a major role in cardiac muscle contractility. Phospholamban (PLN) regulates the function of SERCA2a via its Ser16-phosphorylation. Since it has been proposed that the Ser/Thr residues on cytoplasmic and nuclear proteins are modified by O-linked N-acetylglucosamine (O-GlcNAc), we examined the effect of O-GlcNAcylation on PLN function in rat adult cardiomyocytes. Studies using enzymatic labeling and co-immunoprecipitation of wild type and a series of mutants of PLN showed that PLN was O-GlcNAcylated and Ser16 of PLN might be the site for O-GlcNAcylation. In cardiomyocytes treated with O-(2-acetamido-2-deoxy-d-glucopyranosylidene)amino-N-phenylcarbamate (PUGNAc), the O-GlcNAcylation was significantly increased compared to no...
Losing weight may pollute the blood
Weight loss releases chemical pollutants into the blood, which can stick around, increasing the risk of diabetes, cancer and dementia (Source: New Scientist - Health)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Register for <b><a href="http://www.medmatcha.com" target ="_self">MedMatcha, MedWorm's medical advertising network</a></b>, and receive $5 free advertising.</p></div>
MHRA under pressure to withdraw rosiglitazone
The UK drug regulator has come under fire for failing to act on an expert recommendation to withdraw the type 2 diabetes drug rosiglitazone. (Source: Pulse)
Diabetes education programme cost effective in UK
(Source: PharmacoEconomics and Outcomes News)
Hormone in Hair May Reveal Heart Risk
Title: Hormone in Hair May Reveal Heart RiskCategory: Health NewsCreated: 9/7/2010 10:36:00 AMLast Editorial Review: 9/7/2010 10:36:35 AM (Source: MedicineNet Diabetes General)
No Surprise: Walking, Cycling Linked to Healthier Weights
Title: No Surprise: Walking, Cycling Linked to Healthier WeightsCategory: Health NewsCreated: 9/4/2010 12:10:00 PMLast Editorial Review: 9/7/2010 (Source: MedicineNet Diabetes General)
Winter Sports Tourists at Higher Risk of Heart Attack
Title: Winter Sports Tourists at Higher Risk of Heart AttackCategory: Health NewsCreated: 9/5/2010 10:10:00 AMLast Editorial Review: 9/7/2010 (Source: MedicineNet Diabetes General)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Register for <b><a href="http://www.medmatcha.com" target ="_self">MedMatcha, MedWorm's medical advertising network</a></b>, and receive $5 free advertising.</p></div>
Low-Carb Diets Heavy on Meat May Raise Health Risks
Title: Low-Carb Diets Heavy on Meat May Raise Health RisksCategory: Health NewsCreated: 9/6/2010 6:10:00 PMLast Editorial Review: 9/7/2010 (Source: MedicineNet Diabetes General)
Concern over diabetes drug sales
Concerns have been raised after a diabetes drug that was urged to be withdrawn from sale more than two months ago remains available (Source: Nursing in Practice)
Erectile dysfunction common in Chinese men with Type 2 diabetes
Erectile dysfunction affects three-quarters of Chinese men with Type 2 diabetes, say researchers who add that the majority of such men can be successfully treated with sildenafil citrate. (Source: MedWire News - Diabetes)
The role of PPAR?in pancreatic cell function and survival: therapeutic implications for the treatment of type 2 diabetes mellitus
This article will review the mechanisms by which PPAR?activation acts to maintaincell function and survival in Type 2 diabetes mellitus and highlight some of the current controversies in this field. (Source: Diabetes, Obesity and Metabolism)
Drug withdrawal advice unheeded
A recommendation from the British Medical Journal (BMJ) to withdraw a popular diabetes drug has gone unheeded for two months despite concerns the drug may raise the risk of heart attacks (Source: Pharmacy Europe)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Register for <b><a href="http://www.medmatcha.com" target ="_self">MedMatcha, MedWorm's medical advertising network</a></b>, and receive $5 free advertising.</p></div>
Gender differences in the effects of streptozotocin-induced diabetes on parasympathetic vasodilatation in the rat submandibular gland
Conclusions: Parasympathetic vasodilatation in the rat submandibular gland is diminished equally in diabetic males and females. However, in males diabetes predominantly impairs PGI2- and NO-dependent vasodilatation, whereas in females the contribution of EDHF-mediated pathways are affected and NO-dependent vasodilatation is preferentially maintained. (Source: Archives of Oral Biology)
Erectile dysfunction common in Chinese men with Type 2 diabetes
Erectile dysfunction affects three-quarters of Chinese men with Type 2 diabetes, say researchers who add that the majority of such men can be successfully treated with sildenafil citrate. (Source: MedWire News - Hypertension)
Rosiglitazone: a cautionary tale
(Source: BMJ Online First)
Study finds more Americans bypassing their personal physician when immediate treatment required
(Emory University) Only 45 percent of the 354 million annual visits for acute care in the United States are made to patients' personal physicians, as Americans increasingly make busy emergency departments, specialists or outpatient care departments their first point of contact for treatment of new health problems or a flare up of a chronic condition like asthma or diabetes. (Source: EurekAlert! - Medicine and Health)
Researchers at UC Riverside find solution to cell death problem vexing stem cell research
(University of California - Riverside) Researchers at the University of California, Riverside, have found that a chemically synthesized compound, blebbistatin, can help prevent cell death in human pluripotent stem cells. These cells are of interest to stem cell scientists working on finding therapies for spinal cord injuries, Parkinson's disease, burns, heart disease, diabetes, arthritis, and other ailments. Another advantage of using blebbistatin, say the researchers, is that no human- or animal-derived materials is needed for coating the culture surfaces. (Source: EurekAlert! - Medicine and Health)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Register for <b><a href="http://www.medmatcha.com" target ="_self">MedMatcha, MedWorm's medical advertising network</a></b>, and receive $5 free advertising.</p></div>
Bariatric operations reduce odds of gestational diabetes, cesarean section
(Weber Shandwick Worldwide) Obese women who have bariatric surgical procedures before pregnancy were three times less likely to develop gestational diabetes than women who have bariatric operations after delivery, according to new research findings published in the August issue of the Journal of the American College of Surgeons. (Source: EurekAlert! - Medicine and Health)
Short sleepers at higher risk of diabetes and heart disease
(University of Warwick) People who sleep less than six hours a night may be three times more likely to develop a condition which leads to diabetes and heart disease, according to researchers at the University of Warwick. (Source: EurekAlert! - Medicine and Health)
Premier issue of new Childhood Obesity journal launched by Mary Ann Liebert Inc., publishers
(Mary Ann Liebert, Inc./Genetic Engineering News) Publisher Mary Ann Liebert announced the launch of Childhood Obesity providing physicians, nurses, dietitians, diabetes educators, nutritionists, psychologists, educators and school nurses, community organizers, and policymakers with effective prevention and treatment strategies that promote environmental and policy changes, patient education and motivation tools, and clinical advances in the field. The journal, an outgrowth of Obesity and Weight Management, has a broad mission to be the premier journal and central forum on childhood and adolescent obesity. (Source: EurekAlert! - Medicine and Health)
NIH study shows how insulin stimulates fat cells to take in glucose
(NIH/National Institute of Diabetes and Digestive and Kidney Diseases) Using high-resolution microscopy, researchers at the National Institutes of Health have shown how insulin prompts fat cells to take in glucose in a rat model. The findings were reported in the Sept. 8 issue of the journal Cell Metabolism. (Source: EurekAlert! - Medicine and Health)
The Effect of Features of the Metabolic Syndrome on Atherosclerotic Risk in Relatively Long-Surviving Patients with Type 1 Diabetes
Metabolic Syndrome and Related Disorders , Vol. 0, No. 0. (Source: Metabolic Syndrome and Related Disorders)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Register for <b><a href="http://www.medmatcha.com" target ="_self">MedMatcha, MedWorm's medical advertising network</a></b>, and receive $5 free advertising.</p></div>
Effect of Subcutaneous Glucose Sensor Implantation on Skin mRNA Expression in Pigs
Diabetes Technology & Therapeutics , Vol. 0, No. 0. (Source: Diabetes Technology)
Risk Factors for Microvascular Complications of Diabetes Among South Indian Subjects with Type 2 Diabetes?The Chennai Urban Rural Epidemiology Study (CURES) Eye Study-5
Diabetes Technology & Therapeutics , Vol. 0, No. 0. (Source: Diabetes Technology)
UK watchdog calls for Glaxo's Avandia recall
UK regulators call for the withdrawal across Europe of GlaxoSmith-Kline's diabetes drug Avandia (Source: FT.com - Drugs and Healthcare)
Diabetes and poor glycemic control increase HF risk in CAD patients
Results from the Heart and Soul Study show that patients with stable coronary artery disease (CAD) who have diabetes are at increased risk for developing heart failure (HF) compared with nondiabetics with CAD. (Source: MedWire News - Diabetes)
Smoking and obesity critical to controlling diabetes levels
Report shows improvement in diabetics? health with primary care, writes JOANNE HUNT (Source: The Irish Times - Health)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Register for <b><a href="http://www.medmatcha.com" target ="_self">MedMatcha, MedWorm's medical advertising network</a></b>, and receive $5 free advertising.</p></div>
Kardiomiopatia rozstrzeniowa i przerostowa u płodu matki z cukrzyca ciezarnych - opis przypadku.
We report a case of hypertrophic cardiomyopathy preceded with dilated cardiomyopathy in a fetus of a diabetic mother. The fetal echocardiography at the 23rd week of gestation revealed signs of dilated cardiomyopathy with signs of cardiac failure. Under the echocardiographic monitoring the successful treatment was performed. In spite of poor prognosis, the child was born at the 39th gestation week in a good condition. PMID: 20813091 [PubMed - as supplied by publisher] (Source: Pediatric Endocrinology, Diabetes, and Metabolism)
[The importance of case reports in current pediatric endocrinology and metabolism literature - the analysis of publications indexed in Medline in the years 2004-2009.]
Conclusion: Case reports remain an important contribution to the pediatric literature, mainly fulfilling an essential role in providing information about new medical problems. Medical literature published in Polish is relatively rich in clinical case reports. Publishing a case report in field of endocrinology and metabolism in Pubmed indexed journal is considered reasonable in situations where a new medical condition is being presented (most often a new mutation), a novel therapy has been discovered, the case is interesting or where the publishing of such reports fulfils didactic/educational needs. PMID: 20813090 [PubMed - in process] (Source: Pediatric Endocrinology, Diabetes, and Metabolism)
[Endocrine disorders in children after treatment for brain tumors.]
Authors: Krawczuk-Rybak M Endocrine dysfunction is one of the most common late effect of anticancer treatment. The kind and degree of the disorder depend on tumor location, therapy, especially on the dose of radiotherapy, different sensitivity of the hypothalamo-pituitary axes to irradiation, as well as on the time of treatment. The growth hormone secretion axis is the most vulnerable part, and growth disorders occure most frequently (after a total dose of &gt;30 Gy); then, after a total dose of 50-60 Gy: gonadotropin, ACTH deficiency, and, rarely, TSH deficiency. Spinal irradiation leads to the height loss and disproportionate growth as well as dysfunction of gonads and thyroid gland. Chemotherapy (alkylating agents) deteriorates gonadal function. The recognition, good and early diagn...
[The role of FTO gene polymorphism in the pathogenesis of obesity.]
Authors: Tercjak M, Luczyński W, Wawrusiewicz-Kurylonek N, Bossowski A Both environmental and genetic factors play a role in the pathogenesis of obesity. At present, researchers are examining the genetic background of overweight. Over 100 genes are suspected to influence the obesity. One of those genes is FTO (fat mass and obesity-associated gene). In the manuscript, the relationship between FTO gene polymorphism (AA allele) and overweight, obesity and their consequences are discussed. It was proved, in studies on large number of people, that FTO gene polymorphism is related to higher body mass index, weight and abdominal circumference. Some authors showed that FTO gene polymorphism influences the food intake, energy expanditure and insulin resistance. The expression of FTO gene pro...
[Evaluation of mental development of children with congenital hypothyroidism detected in screening test - personal observations.]
Conclusions: 1. Mental development of the studied children with CH was within normal range. 2. Out of all measured parameters determining mental development, tasks in mathematics, analysis and synthesis, visual concentration and concentration on the hearing level had worst results. 3. The level of TSH in the screening test had no effect on the mental development of children with CH. 4. Out of all environmental factors, parental education influenced the mental development of the studied children. PMID: 20813087 [PubMed - in process] (Source: Pediatric Endocrinology, Diabetes, and Metabolism)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Register for <b><a href="http://www.medmatcha.com" target ="_self">MedMatcha, MedWorm's medical advertising network</a></b>, and receive $5 free advertising.</p></div>
Budowa somatyczna oraz zdolność zachowania równowagi dynamicznej dziewczat uprawiajacych gimnastyke artystyczna.
Conclusion: Body constitution type in the qualified gymnasts is characterised by the prevalence of the ectomorphic component. The study results indicate that female gymnasts are generally slim and lean. It is necessary to monitor BMI in order to exclude weight-related disorders and to observe the changes with age. The poorest result was found when the gymnasts bent in the backward direction as this body position is most difficult to assume and to maintain body equilibrium as compared to all other directions. PMID: 20813086 [PubMed - as supplied by publisher] (Source: Pediatric Endocrinology, Diabetes, and Metabolism)
[Agility in treatment of children with type 1 diabetes - pilot study.]
This study showed that an interesting physical activity resulted in a more eager and systematic effort among examined diabetic children. Its proper organization in time may help in the metabolic control in children with type 1 diabetes. PMID: 20813085 [PubMed - in process] (Source: Pediatric Endocrinology, Diabetes, and Metabolism)
[Overweight, obesity and metabolic syndrome in children with type 1 diabetes melllitus.]
Conclusions: The population of children with type 1 diabetes is characterized by high frequency of overweight/obesity, abdominal obesity, dyslipidemia and hypertension. The features of metabolic syndrome are less frequent. It is worthwhile to monitor the risk for development of cardiovascular diseases in this group of children. PMID: 20813084 [PubMed - in process] (Source: Pediatric Endocrinology, Diabetes, and Metabolism)
L-karnityna obniza stres oksydacyjny indukowany eksperymentalnym niedotlenieniem hypobarycznym.
Conclusion: This study suggests that the administration of L-carnitine can be beneficial in attenuating the oxidative stress associated with exposure to high altitude. PMID: 20813083 [PubMed - as supplied by publisher] (Source: Pediatric Endocrinology, Diabetes, and Metabolism)
[Optimization of monogenic diabetes screening programme - initial report on recruitment efficacy of the TEAM project.]
Conclusions: Periodic reevaluation of patients' data allows a significant increase in the number of candidates subjected to genetic screening and potentially achieving beneficial therapeutic effects by means of pharmacogenetics. PMID: 20813082 [PubMed - in process] (Source: Pediatric Endocrinology, Diabetes, and Metabolism)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Register for <b><a href="http://www.medmatcha.com" target ="_self">MedMatcha, MedWorm's medical advertising network</a></b>, and receive $5 free advertising.</p></div>
[Evaluation of preserved insulin secretion in children and adolescents with type 1 diabetes.]
Conclusion: Repeated measures of c-peptide can enable us to define two groups of patients with immune-mediated diabetes with different levels of disease and metabolic control. PMID: 20813081 [PubMed - in process] (Source: Pediatric Endocrinology, Diabetes, and Metabolism)
Engaging community pharmacists in the primary prevention of cardiovascular disease: protocol for the Pharmacist Assessment of Adherence, Risk and Treatment in Cardiovascular Disease (PAART CVD) pilot study
This study will be a longitudinal pre- and post-test pilot study with a single cohort of up to 100 patients in ten pharmacies. Patients aged 50-74 years with no history of heart disease or diabetes, and taking antihypertensive or lipid-lowering medicines, will be approached for participation. Assessment of cardiovascular risk, medicines use and health behaviours will be undertaken by a research assistant at baseline and following the intervention (6 months). Validated interview scales will be used where available. Baseline data will be used by accredited medicines management pharmacists to generate a report for the treating community pharmacist. This report will highlight individual patients' overall CVD risk and individual risk factors, as well as identifying modifiable health behaviours ...
Licensing process for top selling diabetes drug under fire
Doctors should demand more rigorous proof of long term risks and benefits for diabetes drugsRelated items from OnMedicaAntihypertensive drugs vary in heart attack riskRisk/benefit balance of alteplase shifts quicklyCare homes drug error rate raises concernsFake medicine warning hits cinemasBenefits of statins 'still outweigh risks' (Source: OnMedica Latest News)
Associations of Fetuin-A levels with vascular disease in type 2 diabetes patients with early diabetic nephropathy
Conclusions: The results of this cross-sectional study suggest that lower fetuin-A levels are associated with macrovascular late complications in high-risk type 2 diabetes patients while there are no associations of fetuin-A with metabolic status or microvascular complications. (Source: Cardiovascular Diabetology)
MHRA issues advice and information on the use of rosiglitazone (Avandia®, Avandamet®) in the treatment of diabetes and related BMJ commentaries
Source: MHRA, BMJ, BBC Area: News Following the broadcast of the BBC Panorama programme on rosiglitazone (Avandia®) and concerns over its cardiovascular safety, the MHRA has issued a reminder that there is an ongoing Europe-wide review of the drug's risks and benefits and that it is contributing to current EU assessment of rosiglitazone which is anticipated to reach its conclusion within the next month. The Agency reiterates that "while the European review is ongoing, healthcare professionals are reminded to closely observe the current contraindications and monitoring requirements for rosiglitazone, and to consider alternative treatments where appropriate." Further information for healthcare professionals (CAS communication July 2010) and patients (Q&A document) can be accessed from ...<div id="medworm"><p><b><i>MedWorm Message:</i></b> Register for <b><a href="http://www.medmatcha.com" target ="_self">MedMatcha, MedWorm's medical advertising network</a></b>, and receive $5 free advertising.</p></div>
Sibutramine treatment increases risk of cardiovascular outcomes in high-risk patients
Source: New England Journal of Medicine Area: News The New England Journal of Medicine has published the results of the SCOUT (Sibutramine Cardiovascular Outcomes Trial) study, which prompted the review by the EMEA earlier this year resulting in suspension of its European Marketing Authorisation. &nbsp; SCOUT aimed to determine the long-term effects of sibutramine on rates of cardiovascular events and cardiovascular death in patients at high cardiovascular risk. Participants were overweight or obese, aged 55 or older, with pre-existing cardiovascular disease, type 2 diabetes mellitus, or both. They were randomised to treatment with sibutramine or placebo in addition to a weight management programme. Primary end point was the time from randomisation to the first occurrence of a primary...
Vascular Effects of Ultrafine Particles in Type 2 Diabetics
Conclusions: Inhalation of elemental carbon ultrafine particles for 2 hr transiently activated platelets, and possibly the vascular endothelium, in people with type 2 diabetes. (Source: EHP-in-Press)
Sleep deficiency and Diabetes
This study found a link between sleep and developing diabetes or pre-diabetes. However, studies like these should be of value to those of us already with diabetes because they reveal how complicated this disease is and how we need to think of management in broader terms. We are complicated biological creatures. Diabetes is influenced by various hormonal systems which are in turn influenced by all sorts of stimuli. There is a need to look at ourselves in a holistic way and care for ourselves. In other words, we need to consider our bodies, minds, emotions, lives, stressors, environment - the list could go on. According to the study, getting less than 6 hours of sleep a night increases the likelihood of developing diabetes and heart disease. The researchers looked at data from 1,455 partic...
Medical Journal Urges U.K. to Pull Avandia
The British Medical Journal said diabetes drug Avandia should be withdrawn from sale. But GlaxoSmithKline said it has extensive documentation of the drug's benefits. (Source: WSJ.com: Health)

was particularly interesting because the Finnishpeople have the highest coffees consumption in the world. Thisstudy again found that the incidence of Type 2 mellitusdecreased as the coffees consumption increased. In doing thisstudy, the researchers found that this relationship existed evenwhen the results were statistically adjusted to account forother risk factors, such as age, smoking, weight, alcoholconsumption, and filtered/non-filtered coffees.

As mentioned previously, women have a higher incidence ofinsulin resistance and Type 2 mellitus than men. Thatmay be why the Department of Medicine at the SahlgrenskaUniversity Hospital/Ostra in Goteborg, Sweden, concentratedtheir study on women exclusively.

When they studied 1361 women with no previous incidence of heartdisease or over a period of twenty years, they foundthat the risk of developing Type 2 mellitus for womenwho consumed five or more cups of coffees daily was almost halfof that of women who drank three to four cups each day.

The study also found that it’s possible that the coffees had anaffect on the women’s cholesterol levels, further benefitingtheir overall health.

Finally, the Centre for Nutrition and Food Safety at the Schoolof Biomedical and Molecular Sciences at the University of Surreyin Guildford, United Kingdom, again confirmed the benefit ofdrinking coffees with regards to reducing the risk of Type 2diabetes mellitus.

This study focused on the coffees effects on thegastrointestinal hormones that help regulate insulin secretion.The study found that caffeinated coffees actually lowered theabsorption rate of the glucose, thereby reducing the effects ofthe Type 2 mellitus.

Overall, these studies suggest that drinking caffeinated coffeescan be beneficial to those looking to reduce their risk ofdeveloping or worsening Type 2 mellitus.

© Copyright Randy Wilson, All Rights Reserved.

About the author:Randy has more articles on coffee and coffee beans at Ultimate CoffeesInfo such as Are Coffee Enemas the Real Thing?.