What is Glycemic? The Glycemic Index was discovered in 1981 and is the basis for many recently popular diets, including the South Beach Diet as well as others. The Glycemic Index determines how long certain carbohydrates take to break down and digest in the system. Those with a high rating, take the longest time to break down and do the most damage to the system of someone with diabetes. The good glycemic foods; that is, those with the lower rates, are more desirable not only for diabetics, but for those who are watching their carbohydrate intake through such diets as the South Beach Diet, they should also be aware of what the good glycemic foods are.

Good glycemic foods tend to absorb slowly into the system, allowing the body to break down the refined sugars and starches so that the body can digest them properly. People with Type I and Type II have a difficult time digesting carbohydrates, particularly those that are high on the glycemic index, and this lack of proper digestion makes it difficult for the diabetic to expel glucose from their blood,. While most diabetics are wise to avoid most, if not all carbohydrates, as these are what are the most difficult to digest and break down, certain carbohydrates are better than others for diabetics to consume.

Good glycemic foods tend to have a low score on the Glycemic Index that was developed in 1981 at the University of Toronto. Good glycemic foods are still carbohydrates, but make it easier for the diabetic to digest and are much healthier and preferable than those glycemic foods with high ratings on the Glycemic Index. Substitutions are available for foods that rate high on the Glycemic Index and are widely available in supermarkets and other food stores.

Some of the foods that rate low on the Glycemic Index include most fruits and vegetables, Although fruits and vegetables contain sugar, the sugars contained in these good glyceic foods digest into the system at a lower rate and also provide valuable nutrients to the diabetic, or just about everyone. The only vegetable that a diabetic should

Why fish oils work swimmingly against inflammation and diabetes
Researchers have identified the molecular mechanism that makes omega-3 fatty acids so effective in reducing chronic inflammation and insulin resistance. (Source: ScienceDaily Headlines)
Living arrangements of elderly adults in Catalonia (Spain). The impact of health deterioration on residential independence. - Zueras P, Ajenjo Cosp M.
OBJECTIVES: To identify the effect of health deterioration on residential dependency. MATERIAL AND METHODS: We performed a cross-sectional analysis of the microdata from the Catalan Survey of Health (2006), which features a sample of 3566 individuals aged ... (Source: SafetyLit: All (Unduplicated))
Key to fish oil "magic" found
The mystery of how fish oil helps fight diabetes and heart disease may have been solved (Source: Nursing in Practice)
Vulnerable Elderly Patients and Overactive Bladder Syndrome
(Source: Drugs)
Risk of Potential Drug-Drug Interactions among Brazilian Elderly: A Population-Based, Cross-Sectional Study
(Source: Drugs)
Beta-1 adrenergic receptor polymorphism may increase LVH risk.
The Arg389 polymorphism of the beta-1 adrenergic receptor is associated with a higher risk for left ventricular hypertrophy than is the Gly389 polymorphism in non-diabetic acute myocardial infarction survivors, researchers report. (Source: MedWire News - Diabetes)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Register for <b><a href="http://www.medmatcha.com" target ="_self">MedMatcha, MedWorm's medical advertising network</a></b>, and receive $5 free advertising.</p></div>
Shoulder surgery reduces pain in elderly
CHICAGO, Sept. 3 (UPI) -- U.S. researchers suggest arthroscopic surgery may help reduce pain from torn shoulder muscles in the elderly. Arthroscopy - Surgery - Health - Medicine - United States (Source: Health News - UPI.com)
Treating Diabetes With Severe Personality-Disordered Individuals and Families
Diabetes is an increasingly common chronic medical condition that affects not only patients but also their families. Ensuring adherence to a treatment regimen in diabetic patients is particularly challenging for physicians as well as counselors providing health-focused counseling. However, that challenge is exponentially increased when the patient and one or more family members manifest personality-disordered behavior that interferes with and complicates diabetic treatment. Diabetes as a chronic medical condition is described in the context of individual and family borderline dynamics. (Source: The Family Journal)
Mouse Study May Help Explain Fish Oil?s Benefits
Giving rodents omega-3 fatty acids helped counteract inflammation that can lead to diabetes (Source: The Doctors Lounge - Health News)
Long Term Data Presented at ESC 2010 Further Support the Benefit of TheSirolimus Drug-Eluting Stent Compared to The ENDEAVOR(R) Zotarolimus-Eluting Stent in Important High-Risk Subgroups
STOCKHOLM, September 2, 2010/PRNewswire/ -- &nbsp; - Additional Analysis of 18 Month Data of the SORT OUT III Trial Provides Detail on Safety and Efficacy Outcomes in Patients With Diabetes, Acute Coronary Syndrome, or Treatment of... (Source: Drugs.com - Clinical Trials)
Protein test ups diabetes diagnoses in some races
NEW YORK (Reuters Health) - Efforts to adopt a more accurate test for diagnosing diabetes may have hit a snag. Comparing the age-old oral glucose tolerance test to the newer hemoglobin A1c test confirms earlier evidence that race may influence test results, Danish researchers report. (Source: Reuters: Health)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Register for <b><a href="http://www.medmatcha.com" target ="_self">MedMatcha, MedWorm's medical advertising network</a></b>, and receive $5 free advertising.</p></div>
Enzymatic Function of Two Methylthiotransferase Families [Cell Biology]
Bacterial and eukaryotic transfer RNAs have been shown to contain hypermodified adenosine, 2-methylthio-N6-threonylcarbamoyladenosine, at position 37 (A37) adjacent to the 3'-end of the anticodon, which is essential for efficient and highly accurate protein translation by the ribosome. Using a combination of bioinformatic sequence analysis and in vivo assay coupled to HPLC/MS technique, we have identified, from distinct sequence signatures, two methylthiotransferase (MTTase) subfamilies, designated as MtaB in bacterial cells and e-MtaB in eukaryotic and archaeal cells. Both subfamilies are responsible for the transformation of N6-threonylcarbamoyladenosine into 2-methylthio-N6-threonylcarbamoyladenosine. Recently, a variant within the human CDKAL1 gene belonging to the e-MtaB subfamily was...
Metformin Might Prevent Colorectal, Lung Cancers
The old, cheap diabetes drug metformin is attracting notice as a chemoprevention agent. Medscape Medical News (Source: Medscape Hematology-Oncology Headlines)
Good Taste Noodle MFG Recalls "Egg Noodles and Wonton Skins" Because Of Possible Health Risk
Good Taste Noodle MFG. of Chicago, IL, is recalling its ?EGG NOODLES and WONTON SKINS, labeled with production date from June 19, 2010 to August 19, 2010?, because they have the potential to be contaminated with salmonella, an organism which can cause serious and sometimes fatal infections in young children, frail or elderly people, and others with weakened immune system. Healthy persons infected with salmonella often experience fever, diarrhea (which may be bloody), nausea, vomiting and abdominal pain. (Source: Food and Drug Administration)
NIHR Clinical Lecturer in Endocrinology and Diabetes (NTN(A) attached) - University of Sheffield
Up to two National Institute for Health Research Clinical Lectureship posts are available at the University of Sheffield offering a programme of integrated training in clinical academic medicine. The posts are open to a number of specialties, endocrinology and diabetes being one, and are available for four years or until the post holder obtains their CCT. They must also have successfully completed a PhD or MD and must be eligible for or in posession of a National Training Number (NTN). The deadline for applications is 5 October 2010. For more information please follow the link below. Further details (Source: Society for Endocrinology)
NSAIDs and the risk of accidental falls in the elderly - a systematic review
This review concluded that an increased risk of falls was probable when elderly individuals were exposed to NSAIDs. The lack of controlled trials and the likelihood of recall bias were important limitations of the review and made it difficult to verify results, but the authors' conclusions appeared to reflect the evidence presented. (Source: NLH Later Life Specialist Library Newsfeed)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Register for <b><a href="http://www.medmatcha.com" target ="_self">MedMatcha, MedWorm's medical advertising network</a></b>, and receive $5 free advertising.</p></div>
Differential Contribution of Diabetes and the Ren2 Gene to Glomerular Pathology in Diabetic (mREN-2)27 Rats
Narrowing the scope of utility for (mREN-2)27 rats may help to create better methods for researching diabetic nephropathy. Laboratory Investigation (Source: Medscape Today Headlines)
Fatty acids 'may prevent diabetes'
The secret of how fish oil helps prevent heart disease and diabetes is believed to have been unlocked by scientists who now hope to develop new dietary remedies and drugs to reduce conditions such as type-2 diabetes, heart disease and arthritis. (Source: Nursing Times Breaking News)
Longitudinal examination of cervical volume and vascularization changes during the antepartum and postpartum period using three-dimensional and power Doppler ultrasound
Journal of Perinatal Medicine 38 (5): 461-465 Abstract Objective: To assess longitudinally the changes in cervical volume and vascularization during the peripartum period using three-dimensional ultrasound (3D US) and power Doppler and to determine whether these measures change with gestational complications. Methods: Longitudinal measurements of cervical dimensions by transvaginal 3D US and power Doppler using the virtual organ computer-aided analysis program were performed at 11?14, 22?24, 32?34 weeks' gestation, and at 6 weeks' postpartum in 111 pregnant women. Comparisons were made between women who delivered at term (vs. preterm), nulliparous (vs. parous), with (vs. without) pre-eclampsia and those with (vs. without) gestational diabetes. Results: After establishing reference ...
Pcif1 modulates Pdx1 protein stability and pancreatic {beta} cell function and survival in mice
The homeodomain transcription factor pancreatic duodenal homeobox 1 (Pdx1) is a major mediator of insulin transcription and a key regulator of the &#x003b2; cell phenotype. Heterozygous mutations in PDX1 are associated with the development of diabetes in humans. Understanding how Pdx1 expression levels are controlled is therefore of intense interest in the study and treatment of diabetes. Pdx1 C terminus&#x02013;interacting factor-1 (Pcif1, also known as SPOP) is a nuclear protein that inhibits Pdx1 transactivation. Here, we show that Pcif1 targets Pdx1 for ubiquitination and proteasomal degradation. Silencing of Pcif1 increased Pdx1 protein levels in cultured mouse &#x003b2; cells, and Pcif1 heterozygosity normalized Pdx1 protein levels in Pdx1+/&#x02013; mouse islets, thereby increasing ...
How do organisms make dietary choices?
When given a choice, organisms will choose a diet that maintains a nutritional balance in tune with their needs. That choice, studied in fruit flies for the first time, is regulated by activity in a molecular pathway involved in aging, cancer and diabetes. Humans share the same molecular pathway. The study, the first to be done in a genetically tractable lab animal, could lead to treatments that would "reboot" metabolic pathways in individuals who are obese or suffer from diabetes. (Source: ScienceDaily Headlines)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Register for <b><a href="http://www.medmatcha.com" target ="_self">MedMatcha, MedWorm's medical advertising network</a></b>, and receive $5 free advertising.</p></div>
Children who eat vended snack foods face chronic health problems, poor diet, study finds
School children who consume foods purchased in vending machines are more likely to develop poor diet quality -- and that may be associated with being overweight, obese or at risk for chronic health problems such as diabetes and coronary artery disease, according to new research. (Source: ScienceDaily Headlines)
An Economic Evaluation of Colesevelam when Added to Metformin-, Insulin- or Sulfonylurea-Based Therapies in Patients with Uncontrolled Type 2 Diabetes Mellitus
(Source: PharmacoEconomics)
Cost Effectiveness of Interferon-Gamma Release Assay versus Chest X-Ray for Tuberculosis Screening of BCG-Vaccinated Elderly Populations
(Source: Molecular Diagnosis)
Dr Oz colon polyps raises question of "spontaneous disease" without cause
(NaturalNews) Dr Oz was recently found to have a precancerous colon polyp which was surgically removed. Following this experience, he appears to be surprised and confused about the origin of the condition, and he credits colonoscopy screening with saving his life.Dr Oz even seems to think he has a perfect health record, saying, "I have done everything right. I don't have any family history, and yet I'm high risk now." His personal physician, meanwhile, is implying that even though Dr Oz's "healthy" diet was perfect, it wasn't enough to prevent colon polyps, and therefore you might get them too. (And therefore everybody should get screened...)Dr Jonathan Lapook, went on to say "...no matter what you do, you can't totally eliminate your risk of developing this disease, which is expected to s...
Reviews: Cerebral amyloid angiopathy in East and West
Cerebral amyloid angiopathy, a vasculopathy characterised by the deposition of amyloid fibrils in the arteries and arterioles in the cerebral cortex and meninges, has been reported to be associated with intracerebral haemorrhage and cognitive impairment in the elderly. Advances in neuroimaging and validation of the clinical diagnostic criteria aid in making a correct clinical diagnosis. Associations with Alzheimer's disease, asymptomatic microbleeds and white matter changes on neuroimaging have an influence on the clinical treatment for patients with probable cerebral amyloid angiopathy. Reviewing the reports from Asian countries, we found that patients with cerebral amyloid angiopathy have a strong age?related prevalence and a consistent association with dementia, but a weaker correlati...<div id="medworm"><p><b><i>MedWorm Message:</i></b> Register for <b><a href="http://www.medmatcha.com" target ="_self">MedMatcha, MedWorm's medical advertising network</a></b>, and receive $5 free advertising.</p></div>
Mild BNP may indicate LV dysfunction in diabetics
Dutch researchers report that slightly elevated B-type natriuretic peptide levels are associated with increased left ventricular mass and diastolic dysfunction in patients with Type 2 diabetes. (Source: MedWire News - Diabetes)
Celebrating World Diabetes Day and preparing for the battles ahead
(Source: Diabetes Research and Clinical Practice)
Muscle relaxants raise fracture risk in elderly
(Source: Reactions)
Allopurinol: Fatal drug hypersensitivity syndrome with toxic epidermal necrolysis in an elderly patient: case report
(Source: Reactions)
Antibacterials/sertraline: Hepatitis in an elderly patient: case report
(Source: Reactions)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Register for <b><a href="http://www.medmatcha.com" target ="_self">MedMatcha, MedWorm's medical advertising network</a></b>, and receive $5 free advertising.</p></div>
Bevacizumab/pegaptanib/ranibizumab: Retinal pigment epithelial tears in elderly patients: 20 case reports
(Source: Reactions)
Bortezomib/dexamethasone: Acute myocardial infarction (first report with bortezomib) in an elderly patient: case report
(Source: Reactions)
Calcifediol/calcium/colecalciferol: Renal failure and hypercalcaemia in an elderly patient: case report
(Source: Reactions)
Candesartan cilexetil: Oral angioedema in an elderly patient: case report
(Source: Reactions)
Corticosteroids/leflunomide: Aspergillus tracheobronchitis in an elderly patient: case report
(Source: Reactions)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Register for <b><a href="http://www.medmatcha.com" target ="_self">MedMatcha, MedWorm's medical advertising network</a></b>, and receive $5 free advertising.</p></div>
Danazol/simvastatin interaction: Fatal rhabdomyolysis in an elderly patient: case report
(Source: Reactions)
Dihydrocodeine: Erythema multiforme major in an elderly patient: case report
(Source: Reactions)
Dipyrone: Neutropenia in an elderly patient: case report
(Source: Reactions)
Dovitinib: First report of peripheral neuropathy in an elderly patient: case report
(Source: Reactions)
Epinephrine: Tako-tsubo cardiomyopathy in an elderly patient: case report
(Source: Reactions)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Register for <b><a href="http://www.medmatcha.com" target ="_self">MedMatcha, MedWorm's medical advertising network</a></b>, and receive $5 free advertising.</p></div>
Epirubicin: Bladder perforation (first report) with extravasation, cellulitis, fibrosis, necrosis and inflammation following intravesical administration in elderly patients: 2 case report
(Source: Reactions)
Fentanyl/propofol: Coronary spasm in an elderly patient: case report
(Source: Reactions)
Gemcitabine: Digital ischaemia in elderly patients: 2 case reports
(Source: Reactions)
Hydrocortisone/methotrexate/prednisone: Septic arthritis in an elderly patient: case report
(Source: Reactions)
Imatinib: Intraperitoneal haemorrhage from GIST in an elderly patient: case report
(Source: Reactions)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Register for <b><a href="http://www.medmatcha.com" target ="_self">MedMatcha, MedWorm's medical advertising network</a></b>, and receive $5 free advertising.</p></div>
Levofloxacin: Torsade de pointes in an elderly patient: case report
(Source: Reactions)
Lithium: Lithium toxicity in an elderly patient: case report
(Source: Reactions)
Magnesium citrate/magnesium oxide: Hypermagnesaemia and perforative peritonitis leading to shock, in an elderly patient: case report
(Source: Reactions)
Mercaptopurine: Visceral leishmaniasis (first report) in an elderly patient: case report
(Source: Reactions)
Mitomycin: Interstitial pneumonitis in an elderly patient: case report
(Source: Reactions)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Register for <b><a href="http://www.medmatcha.com" target ="_self">MedMatcha, MedWorm's medical advertising network</a></b>, and receive $5 free advertising.</p></div>
Paclitaxel: Chronic fibrosing interstitial pneumonitis in an elderly patient: case report
(Source: Reactions)
Ranibizumab: Vitreomacular attachment leading to macular hole in an elderly patient: case report
(Source: Reactions)
Sufentanil: Intrathecal catheter granuloma (first report) in an elderly patient: case report
(Source: Reactions)
Tc 99m sestamibi: Erythroderma in an elderly patient: case report
(Source: Reactions)
Terbinafine: Drug-induced hypersensitivity syndrome in an elderly patient: case report
(Source: Reactions)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Register for <b><a href="http://www.medmatcha.com" target ="_self">MedMatcha, MedWorm's medical advertising network</a></b>, and receive $5 free advertising.</p></div>
Teriparatide: Osteosarcoma in an elderly patient following radiation therapy: case report
(Source: Reactions)
Influence of Left Ventricular Dysfunction (Diastolic Versus Systolic) on Long-Term Prognosis in Patients With Versus Without Diabetes Mellitus Having Elective Peripheral Arterial Surgery
In conclusion, diabetic patients with PAD have an increased prevalence of isolated systolic and combined LVD. In patients with PAD the presence of isolated diastolic, systolic, or combined LVD was independently and equally associated with increased cardiovascular mortality, irrespective of the concomitant presence of DM. (Source: The American Journal of Cardiology)
If you have prediabetes, do something about it now
Prevent or delay diabetes by changing your lifestyle. (Source: MayoClinic.com Full Feed)
Children And Vending Machines Don?t Mix Well
(Ivanhoe Newswire) - School children who consume foods purchased in vending machines are more likely to develop poor diet quality ? and that may be associated with being overweight, obese or at risk for chronic health problems such as diabetes and coronary artery disease, according to research from the University of Michigan Medical School. (Source: Medical Headlines From Ivanhoe.com)
Age No Barrier to Oral Anticoagulants (CME/CE)
(MedPage Today) -- Age alone shouldn't deter appropriate oral anticoagulant use in elderly atrial fibrillation patients, according to a review. (Source: MedPage Today Cardiovascular)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Register for <b><a href="http://www.medmatcha.com" target ="_self">MedMatcha, MedWorm's medical advertising network</a></b>, and receive $5 free advertising.</p></div>
Acute Onset of Abdominal Pain in a 76-Year-Old Man
An elderly man presents with sudden-onset abdominal pain centered in the epigastrium that is described as deep and burning. Hyperactive bowel sounds are heard on auscultation. What is the diagnosis? Medscape (Source: Medscape Emergency Medicine Headlines)
NPRI partners launch £10m funding call to tackle major health threats
A £10 million fund has been committed by The National Prevention Research Initiative (NPRI), managed by the MRC, in its drive to prevent some of the UK’s most prominent diseases and conditions, such as cancer, diabetes, obesity, stroke and dementia. (Source: Medical Research Council Funding News)
Potting compost to carry warnings after gardener gets Legionnaire's
Bags of potting compost are to carry health warnings after an elderly Scot contracted Legionnaire's disease through a cut on his hand. (Source: Scotsman.com News - Health)
Elevated blood glucose disrupts normal immune responses in diabetics
UK researchers suggest that elevated blood glucose levels in patients with diabetes can cause competitive inhibition of immune receptors and hinder the body?s ability to fight infection. (Source: MedWire News - Diabetes)
Involvement of the Basilar Artery in Diabetes Mellitus: An MRI Study of Brainstem Infarctions
Eur Neurol 2010;64:230–235 (DOI:10.1159/000319924) (Source: Karger Publishers)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Register for <b><a href="http://www.medmatcha.com" target ="_self">MedMatcha, MedWorm's medical advertising network</a></b>, and receive $5 free advertising.</p></div>
Peroxisome Proliferator-Activated Receptor-γ Agonist Rosiglitazone Prevents Albuminuria but Not Glomerulosclerosis in Experimental Diabetes
Am J Nephrol 2010;32:393–402 (DOI:10.1159/000320129) (Source: Karger Publishers)
Diabetes Drug Metformin Linked to Lower Lung Cancer Rate in Mice
Findings reflect those of population studies in humans, researchers say (Source: Pharmacy News - Doctors Lounge)
Bariatric Surgery Cost-Effective in Very Obese With Diabetes
Both gastric bypass and gastric banding are cost-effective ways to reduce diabetes-associated complications and mortality among severely obese individuals with diabetes, according to research published in the September issue of Diabetes Care. (Source: Modern Medicine)
Human-IAPP disrupts the autophagy/lysosomal pathway in pancreatic ?-cells: protective role of p62-positive cytoplasmic inclusions
Human-IAPP disrupts the autophagy&#47;lysosomal pathway in pancreatic &#946;-cells: protective role of p62-positive cytoplasmic inclusions Cell Death and Differentiation advance online publication, September 3, 2010. doi:10.1038/cdd.2010.111 Authors: J F Rivera, T Gurlo, M Daval, C J Huang, A V Matveyenko, P C Butler & S Costes (Source: Cell Death and Differentiation)
Lead Exposure May Delay Puberty in Girls
Occurred even at blood levels below those recommended for treatment, NIH found (Source: The Doctors Lounge - Endocrinology and Diabetes)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Register for <b><a href="http://www.medmatcha.com" target ="_self">MedMatcha, MedWorm's medical advertising network</a></b>, and receive $5 free advertising.</p></div>
14th Annual Meeting of the Neuroendocrinology Section of the German Society of Endocrinology (DGE) and 20th Anniversary of an Argentine-German Collaboration
Experimental and Clinical Endocrinology &amp; Diabetes 2010; 08Article in Thieme eJournal:Table of contents  |  Congress (Source: Experimental and Clinical Endocrinology and Diabetes)
[Editorial] Perils of asthma research in vulnerable groups
To coincide with the annual European Respiratory Society meeting, in Barcelona, on Sept 18?22, The Lancet today focuses on asthma and respiratory diseases. WHO estimates that asthma affects 300 million people worldwide, and vulnerable groups?particularly children and elderly people?can be especially difficult to treat. Two Reviews in this issue focus on these groups, for which asthma is associated with substantial morbidity and mortality, and is characterised by scarce data from research. (Source: LANCET)
[Comment] The impact of asthma guidelines
Asthma prevalence is increasing and the economic burden is substantial. Although cost-effective therapies are available, drug regimens are not always adhered to. The impact of asthma guidelines needs re-assessing, not only for patients' care but also for a broader framework, especially because the interface between big pharma and academic institutions is under increasing scrutiny. The initial iteration of the Canadian asthma guidelines were first published in the 1990s. The primary focus of the guidelines has been an emphasis on the role of inflammation and the primary efficacy of inhaled corticosteroids. Additionally, the Canadian guidelines have focused on the importance of asthma control rather than classifying asthma on the basis of the level of severity. The guidelines use a schematic...
FVB mouse genotype confers susceptibility to OVE26 diabetic albuminuria
OVE26 (OVE) diabetic mice on the inbred strain FVB are a valuable model of diabetic nephropathy that excretes the highest amount of urine albumin of all diabetic mouse models. Crossing of OVE mice to C57BL6 or DBA2 mice reduced albuminuria 17-fold in F1 diabetic offspring without reducing diabetes. When comparing renal histology of OVE mice on the FVB background to F1 C57BL6 crosses, we found that the F1 kidneys had significantly smaller glomeruli, much less albumin accumulation in tubules, reduced mesangial matrix expansion, and less interstitial fibrosis. A genome scan of 108 OVE-positive N2 offspring for albuminuria revealed one significant peak on chromosome 11 and nearly significant peaks on chromosomes 9, 13, and 19. Homozygosity for the FVB genotype for peaks on chromosomes 11, 13, ...
The pleiotropic actions of rosuvastatin confer renal benefits in the diabetic Apo-E knockout mouse
In conclusion, in the diabetic Apo-E&ndash;/&ndash; mouse, rosuvastatin confers renal benefits that are independent of lipid lowering and equivalent or greater to those observed with candesartan. The combination treatment is not superior to monotherapies. (Source: AJP: Renal Physiology)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Register for <b><a href="http://www.medmatcha.com" target ="_self">MedMatcha, MedWorm's medical advertising network</a></b>, and receive $5 free advertising.</p></div>
School Children Who Eat Vending Machine Foods Face Increased Risks for Chronic Health Problems, Poor Diet
September 2, 2010 (U-M) - School children who consume foods purchased in vending machines are more likely to develop poor diet quality ? and that may be associated with being overweight, obese or at risk for chronic health problems such as diabetes and coronary artery disease, according to research from the University of Michigan Medical School.   The study also looked at foods sold in school stores, snack bars and other related sales that compete with USDA lunch program offerings and found that these pose the same health and diet risks in school-aged children. read more (Source: Diabetes News from dLife.com)
Acasti Pharma Inc. Reports Positive Impacts on Cardiometabolic Associated Disorders
LAVAL, Quebec, Sept. 2, 2010 (GLOBE NEWSWIRE) -- This release replaces and supersedes the press release sent earlier today. Acasti Pharma Inc., a subsidiary of Neptune Technologies & Bioressources Inc. ("Neptune") (Nasdaq:NEPT) (TSX-V:NTB) reports significant results on the effects of its anti-dyslipidemic investigational drug candidate CaPre(tm) on C-reactive protein (CRP) levels, a biomarker of CardioVascular Disease risk (CVD) and associated with diabetes and obesity. (Source: Medical News (via PRIMEZONE))
Puzzling claims over brain games
Conclusion This study has some strengths, including the large number of patients followed and the long follow-up period. Furthermore, its clinical evaluations and assessments of cognitive function were based on validated measures. The participants also represent a broad spectrum of cognitive function, ranging from no impairment to dementia. However, the study also has limitations. It did not make adjustments for other factors (called confounders) which might contribute to the development of Alzheiner?s. For example, certain educational, social and genetic factors may have differed between the groups, which were not accounted for in the researchers? analyses. Importantly, the assessment of cognitive activity was based on a composite measure. Since only seven cognitive activities we...
Because You Ought to do Right by Your Parents
In our aging society, taunting decisions are being made for elderly parents by well meaning children every day. 'Parental Controls' by Faye Hollins-Moore (available at www.Amazon.com) is a guidance manual written in fiction form to assist in the decision making process. (Source: Disabled World)
How Fish Oil Fights Inflammation
Omega-3 fatty acids work via a specific receptor and may combat diabetes as well (Source: ScienceNOW)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Register for <b><a href="http://www.medmatcha.com" target ="_self">MedMatcha, MedWorm's medical advertising network</a></b>, and receive $5 free advertising.</p></div>
Moving Diabetes Genetics Beyond Genome-Wide Association Studies
Dr. Ali Torkamani summarizes key sessions from the American Diabetes Association's 70th Scientific Sessions and discusses how genetic investigations can assist in our understanding of type 1 and type 2 diabetes. Medscape Genomic Medicine (Source: Medscape Pathology Headlines)
Balancing act for elderly myeloma
(Source: Blood)
Melphalan and prednisone plus thalidomide or placebo in elderly patients with multiple myeloma
In conclusion, MPT had a significant antimyeloma effect, but this did not translate into improved survival. This trial was registered at www.clinicaltrials.gov as #NCT00218855. (Source: Blood)
Lower Blood Pressure Goal Benefits African-Americans with Chronic Kidney Disease, Protein in the Urine
Source: National Institute of Diabetes and Digestive and Kidney Diseases - Related MedlinePlus Pages: African-American Health, Kidney Diseases (Source: MedlinePlus Health News)
Long Term Data Presented at ESC 2010 Further Support the Benefit of The CYPHER(R) Sirolimus Drug-Eluting Stent Compared to The ENDEAVOR(R) Zotarolimus-Eluting Stent in Important High-Risk Subgroups
Additional Analysis of 18 Month Data of the SORT OUT III Trial Provides Detail on Safety and Efficacy Outcomes in Patients With Diabetes, Acute Coronary Syndrome, or Treatment of Multiple Lesions STOCKHOLM, September 2, 2010 (HSMN NewsFeed) --Three ne... Devices, Interventional CardiologyCordis, CYPHER, Sirolimus, Drug Eluting Stent, Zotarolimus, Medtronic (Source: HSMN NewsFeed)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Register for <b><a href="http://www.medmatcha.com" target ="_self">MedMatcha, MedWorm's medical advertising network</a></b>, and receive $5 free advertising.</p></div>
High-Risk Pools for the Sick and Uninsured Under Health Reform: Too Little and Thus Too Late
ABSTRACT&nbsp;&nbsp;Democrats and Republicans have turned to the concept of ?high-risk pools? to provide health care for those Americans who face the dual challenge of uninsurance and serious health difficulties. Under the Patient Protection and Affordable Care Act (PPACA), these ?high-risk? individuals will receive extensive help and regulatory protections, in concert with a new system of health insurance exchanges. However, these federal provisions do not become operational until 2014. As an interim measure, PPACA provides $5 billion for temporary, federally funded high-risk pools, now known as the Pre-Existing Condition Insurance Plan (PCIP). This analysis explores the adequacy of such funding. Using 2005/06 data from the National Health and Nutrition Examination Survey (N...
Epidemiology, costs and burden of osteoporosis in Mexico
Discussion&nbsp;&nbsp;Hip fractures worldwide are projected to increase from 1.2 million in the 1990s to 2.6 million by 2025 and to 4.5 million by 2050, assuming no change in age- and sex-specific incidence. The vast majority of hip fractures in the twenty-first century will occur in developing countries; Asia and Latin America are estimated to be the two regions that will have the highest increases [2]. Osteoporosis and fragility fracture have become a focus of research in Mexico, and the National Institutes of Health in Mexico have recently recognized osteoporosis as a public health problem. However, osteoporosis still remains a greatly undetected and untreated national health priority disease because of the lack of awareness at all levels. Content Type Journal ArticleDOI 1...
Self-Reported Urge Urinary Incontinence (UUI) Among Older Mexican?American Men: Risk Factors and Psycho-Social Consequences
This study is the first to examine risk factors for and consequences of self-reported UUI among older Mexican?American men using a large community-based survey. Content Type Journal ArticleDOI 10.1007/s10903-010-9383-zAuthors K. Gerst, Institute of Gerontology, College of Public Health, University of Georgia, 255 E. Hancock Ave., Athens, GA 30602, USAL. A. Ray, Preventive Medicine and Community Health, University of Texas Medical Branch, Galveston, TX USAR. Samper-Ternent, Sealy Center on Aging, University of Texas Medical Branch, 301 University Blvd, 77555 Galveston, TX USAD. V. Espino, School of Medicine, University of Texas Health Sciences Center, San Antonio, TX USAK. S. Markides, Sealy Center on Aging, University of Texas Medical Branch, 301 University Blvd, 77555 Galveston,...
Plasma osteoprotegerin, arterial stiffness, and mortality in normoalbuminemic Japanese hemodialysis patients
Conclusions&nbsp;&nbsp;In long-term normoalbuminemic Japanese hemodialysis patients, with low prevalence of inflammation, OPG levels were strongly linked with both arterial stiffness and worse outcome. Content Type Journal ArticleDOI 10.1007/s00198-010-1377-0Authors A. Nakashima, Department of Advanced Nephrology, Graduate School of Biomedical Sciences, Hiroshima University, 1-2-3 Kasumi Minami-Ku, Hiroshima, 734-8551 JapanJ. J. Carrero, Divisions of Renal Medicine and Baxter Novum, Department of Clinical Science, Intervention and Technology, Karolinska Institutet, Stockholm, SwedenA. R. Qureshi, Divisions of Renal Medicine and Baxter Novum, Department of Clinical Science, Intervention and Technology, Karolinska Institutet, Stockholm, SwedenT. Hirai, Department of Internal Medi...
Better collaboration between primary and secondary doctors is key to integrated care
(Source: BMJ Online First)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Register for <b><a href="http://www.medmatcha.com" target ="_self">MedMatcha, MedWorm's medical advertising network</a></b>, and receive $5 free advertising.</p></div>
EMAS Publishes Position Statements About the Post-Reproductive Health of Women
September 2, 2010 (EurekAlert) - Elsevier announced today the publication of four important position statements from the European Menopause and Andropause Society (EMAS) in the journal Maturitas on common management problems in the post-reproductive health of women. The statements cover the management of the menopause in the context of obesity, epilepsy, endometriosis and premature ovarian failure. Each statement has summary recommendations as a quick aid for the busy clinician. read more (Source: Diabetes News from dLife.com)
Americans Blind to the Obesity Epidemic
Harris Interactive/HealthDay poll finds 30 percent of those overweight think they're normal size (Source: The Doctors Lounge - Cardiology)
Diabetes 2 Drug Metformin May Protect Against Lung Cancer In Smokers
Two studies reveal that smokers may have a significantly lower risk of developing lung cancer and colorectal cancer with the drug metformin, which is commonly prescribed for diabetes type 2 treatment, the medical journal Cancer Prevention Research informs. Metformin, originally sold as Glucophage, is the first-line drug of choice for diabetes type 2 patients, especially those who are obese or overweight, as well as diabetes patients with normal kidney function. Metformin may have the following brand names: Fortamet, Glucophage, Glucophage XR, Glumetza, or Riomet... (Source: Health News from Medical News Today)
Halozyme Begins Phase 2 Clinical Trials With Insulin Analogs Lispro and Aspart With rHuPH20 In Type 1 And Type 2 Diabetes
Halozyme Therapeutics, Inc. (Nasdaq: HALO) today announced the initiation of two Phase 2 Ultrafast Insulin treatment studies that utilize its rHuPH20 hyaluronidase enzyme (PH20) in combination with the two leading commercially available mealtime analogs: insulin aspart, the active ingredient in NovoLog®, and insulin lispro, the active ingredient in Humalog®. (Source: Pharmaceutical Online News)
Obesity runs Cali a $21B tab, and $24B for diabetes
Rates of obesity and diabetes in California are well above the national targets and goals. In the state, costs related to obesity are reported to be $21 billion, and as the rate of diabetes jumped 26 percent from 2001 to 2007, direct costs related to the comorbidity have been reported to soak up $24 billion, according to the results of the most recent California Health Interview Survey. (Source: Cardiovascular Business News)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Register for <b><a href="http://www.medmatcha.com" target ="_self">MedMatcha, MedWorm's medical advertising network</a></b>, and receive $5 free advertising.</p></div>
Acasti Pharma Inc. Reports Positive Impacts on Obesity and Cardiometabolic Associated Disorders
LAVAL, Quebec, Sept. 2, 2010 (GLOBE NEWSWIRE) -- Acasti Pharma Inc., a subsidiary of Neptune Technologies & Bioressources Inc. ("Neptune") (Nasdaq:NEPT) (TSX-V:NTB) reports significant results on the effects of its anti-dyslipidemic investigational drug candidate CaPre(tm) on C-reactive protein (CRP) levels, a biomarker of CardioVascular Disease risk (CVD) and associated with diabetes and obesity. (Source: Medical News (via PRIMEZONE))
Central retinal thickness measured with HD-OCT shows a weak correlation with visual acuity in eyes with CSME
Conclusion Correlations between RT and BCVA in CSME are only present when the central 500-&micro;m-diameter circle is involved. However, even in this circumstance, a correlation was found in only 48.8% of the cases. RT cannot, therefore, be used as a surrogate outcome for visual acuity changes. (Source: British Journal of Ophthalmology)
Plasma levels of vascular endothelial growth factor and pigment epithelium-derived factor before and after intravitreal injection of bevacizumab
Conclusions The decreased levels of blood VEGF after an intravitreal injection of bevacizumab indicate that bevacizumab enters the general circulation and may also affect the PEDF levels. Thus, we should carefully examine patients for systemic changes and the fellow eye after an intravitreal injection of bevacizumab. (Source: British Journal of Ophthalmology)
Insulin resistance and diabetic macular oedema in type 2 diabetes mellitus
Conclusions The findings of this study indicate a relationship between insulin resistance and cystoid macular oedema that unrelated to the use of insulin. Insulin treatment was associated with diffuse macular oedema. (Source: British Journal of Ophthalmology)
Agent Orange Cases Expanded; Added Costs Raise Fiscal Concerns
The Associated Press/Washington Post: Hundreds of thousands of Vietnam War veterans are receiving disability compensation for diseases normally associated with aging - not combat - because of the possibility of a link Agent Orange exposure. The diseases in question range from diabetes, for which 270,000 veterans receive Agent Orange-related checks, to erectile dysfunction. "And taxpayers may soon be responsible for even more: VA said Monday that it will add heart disease, Parkinson's disease and certain types of leukemia to the list of conditions that might be connected to Agent Orange... (Source: Health News from Medical News Today)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Register for <b><a href="http://www.medmatcha.com" target ="_self">MedMatcha, MedWorm's medical advertising network</a></b>, and receive $5 free advertising.</p></div>
Sublobar Resection for Early-Stage Lung Cancer
The use of sublobar resection techniques (anatomic segmentectomy; extended wedge) in the treatment of early-stage non-small cell lung cancer has been associated with increased local recurrence rates compared with lobectomy. Recent data, however, have suggested that sublobar resection of smaller tumors (especially those ?2 cm) can be performed with no significant difference in local recurrence or long-term survival. These findings have particular relevance in elderly patients and in those patients who may be at high risk for lobectomy because of underlying medical comorbidities. Careful patient selection on the basis of individualized assessment of specific patient and tumor characteristics will aid in selecting the optimal approach. For larger tumors, or when adequate surgical margins ar...
Familial prevalence of autoimmune disorders in multiple sclerosis in Northern Greece
Conclusions: There is a longitudinally increased frequency of additional autoimmune disorders among multiple sclerosis family members, probably related to immunomodulatory therapy. (Source: Multiple Sclerosis)
Coronary revascularisation in the patient with diabetes: balancing risk and benefit
(Source: Heart)
Association between admission hypoglycaemia and in-hospital and 3-year mortality in older patients with acute myocardial infarction
Conclusions In older patients with AMI, increased as well as decreased admission FPG levels could predict higher in-hospital and 3-year mortality. There was a striking U-shaped relationship between admission FPG levels and short- and long-term mortality. An initial admission FPG level &ge; 5.1 to&le;7.0&nbsp;mmol/l may be desirable because it was associated with better clinical outcomes. (Source: Heart)
Unrecognised myocardial infarction and long-term risk of heart failure in the elderly: the Rotterdam Study
Conclusion Unrecognised MI detected by electrocardiography yields a long-term risk of heart failure equivalent to recognised MI in men, but is not significantly related to heart failure in women. In the light of the high incidence of both unrecognised MI and heart failure in the elderly, it may be worthwhile for both doctors and patients to improve responsiveness to typical and atypical symptoms of MI. (Source: Heart)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Register for <b><a href="http://www.medmatcha.com" target ="_self">MedMatcha, MedWorm's medical advertising network</a></b>, and receive $5 free advertising.</p></div>
Unilife Corporation Secures FDA 510k Clearance For The Unitract? 1mL Tuberculin Syringe
Unilife Corporation ("Unilife" or "Company") (Nasdaq: UNIS, ASX: UNS), announced that its Unitract? Tuberculin (TB) Syringe has received 510(k) market clearance from the U.S. Food and Drug Administration (FDA). The Unitract? TB syringe is a variant of the Unitract? 1mL Insulin Syringe for which Unilife secured FDA clearance earlier this year. Unlike insulin syringes which are primarily used by people with diabetes, TB syringes are used for the administration of a range of therapeutic drugs and vaccines within acute-care hospitals and other healthcare facilities... (Source: Health News from Medical News Today)
Predictors of Inpatient Death and Complications among Postoperative Elderly Patients with Metastatic Brain Tumors
Conclusions&nbsp;&nbsp;Surgical resection of brain metastases among the elderly up to the ninth decade of life is feasible. Age older than 80&nbsp;years and higher Charlson comorbidity scores were found to be important prognostic factors for inpatient outcome. Incorporating these factors into preoperative decision making may help to select appropriately those elderly candidates for neurosurgical intervention. Content Type Journal ArticleDOI 10.1245/s10434-010-1299-2Authors Rachel Grossman, Neuro-Oncology Surgical Outcomes Research Laboratory, Department of Neurosurgery and Oncology, Johns Hopkins University School of Medicine, Baltimore, MD USADebraj Mukherjee, Neuro-Oncology Surgical Outcomes Research Laboratory, Department of Neurosurgery and Oncology, Johns Hopkins Univers...
Azathioprine as an alternative treatment in primary hypophysitis
Abstract&nbsp;&nbsp;Primary hypophysitis (PH) is an unusual disorder characterized by inflammatory infiltration of the pituitary gland with various degree of pituitary dysfunction. Glucocorticoids are the treatment of choice in the majority of patients. Still, in patients with poor response in glucocorticoids or when their administration is accompanied with serious side effects, the use of alternative agents should be considered; up to now, data on other therapeutic approaches remains scant mainly due to the rarity of the disease. Among them, the immunosuppressant azathioprine could represent an effective and safe alternative. In this article, we present our clinical experience of two cases with PH successfully treated with azathioprine following serious side effects after initial tr...
Telemedicine Helps Native Americans
Source: Carolyn Bloch, Federal Telemedicine News Content: &#8220;The University of California, Davis School of Medicine is using grant funding to train Native American communities in the state. The training sites include the Round Valley Indian Tribes of Covelo, Mendocino County, and communities served by Northern Valley Indian Health Inc. that includes Glenn County and portions [...] (Source: ICMCC: The International Council on Medical and Care Compunetics)
Bone Loss in Diabetes: Use of Antidiabetic Thiazolidinediones and Secondary Osteoporosis
Abstract&nbsp;&nbsp;Clinical evidence indicates that bone status is affected in patients with type 2 diabetes mellitus (T2DM). Regardless of normal or even high bone mineral density, T2DM patients have increased risk of fractures. One class of antidiabetic drugs, thiazolidinediones (TZDs), causes bone loss and further increases facture risk, placing TZDs in the category of drugs causing secondary osteoporosis. Risk factors for development of TZD-induced secondary osteoporosis are gender (women), age (elderly), and duration of treatment. TZDs exert their antidiabetic effects by activating peroxisome proliferator-activated receptor-? (PPAR-?) nuclear receptor, which controls glucose and fatty acid metabolism. In bone, PPAR-? controls differentiation of cells of mesenchymal and hemato...<div id="medworm"><p><b><i>MedWorm Message:</i></b> Register for <b><a href="http://www.medmatcha.com" target ="_self">MedMatcha, MedWorm's medical advertising network</a></b>, and receive $5 free advertising.</p></div>
The Role of Renin-Angiotensin Agents in Altering the Natural History of Type 2 Diabetes Mellitus
Abstract&nbsp;&nbsp;Type 2 diabetes mellitus (T2DM) is a major risk factor for cardiovascular disease (CVD) morbidity and mortality worldwide. Renin-angiotensin system (RAS) blockers have been indispensable in diminishing the macrovascular and microvascular complications of diabetes. In addition, cumulative evidence from retrospective studies pointed toward a beneficial effect of RAS agents in preventing the development and progression of T2DM. This disease-modifying potential of RAS blockers has been substantiated by recent prospective trials. Contemporary concepts regarding the natural history of T2DM and the pathophysiologic processes involved have increased our understanding of the mechanisms underlying the therapeutic potential of these agents in diabetes management. In addition...
Original Article: Potential CYP2C9?mediated drug?drug interactions in hospitalized type 2 diabetes mellitus patients treated with the sulphonylureas glibenclamide, glimepiride or glipizide
Abstract.? (Source: Journal of Internal Medicine)
NHS Confederation Comments On Age UK Report On Malnutrition Among Elderly Hospital Patients
Commenting on the report from Age UK claiming that one in three nurses would not trust the NHS to care for an elderly relative, deputy policy director Jo Webber said the NHS has made huge strides on nutrition but more still remains to be done. Jo Webber, deputy director of policy at the NHS Confederation, said: "Nutrition is an important part of helping people to get better, as well as a vital indicator of how well patients are cared for in hospital... (Source: Health News from Medical News Today)
Surgery To Repair Torn Shoulder Muscles In The Elderly Can Reduce Pain And Improve Function
Repairing torn shoulder muscles in elderly patients is often discouraged because of fears of complications. But a new study conducted at Rush University Medical Center has shown that minimally invasive, or arthroscopic, surgery can significantly improve pain and function. The study has just been published online in Arthroscopy: The Journal of Arthroscopic and Related Surgery and will appear in the October issue. "In people over the age of 70, pain is the main issue, and pain relief is a fairly reliable outcome after surgery," said orthopedic surgeon Dr. Nikhil Verma, who led the study... (Source: Health News from Medical News Today)
New Study Singles Out Factors Linked To Cognitive Deficits In Type 2 Diabetes
Older adults with diabetes who have high blood pressure, walk slowly or lose their balance, or believe they're in bad health, are significantly more likely to have weaker memory and slower, more rigid cognitive processing than those without these problems, according to a new study published by the American Psychological Association. These three health factors stood out from more than a dozen suspected to shape how Type 2 diabetes is frequently shadowed by cognitive impairment, including dementia... (Source: Health News from Medical News Today)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Register for <b><a href="http://www.medmatcha.com" target ="_self">MedMatcha, MedWorm's medical advertising network</a></b>, and receive $5 free advertising.</p></div>
Growing Obesity, Diabetes Epidemics In California
A majority of adults in California are obese or overweight, and more than 2 million have been diagnosed with diabetes, according to a new study from the UCLA Center for Health Policy Research. Both conditions - which are related to each other as well as to heart disease - increased significantly in just six years, with the prevalence of diabetes alone jumping nearly 26 percent between 2001 and 2007. The "epidemic" of obesity and diabetes leaves no racial, ethnic, economic or geographic segment of the state unscathed, according to the researchers... (Source: Health News from Medical News Today)
Diabetes Drug Metformin Linked to Lower Lung Cancer Rate in Mice
Title: Diabetes Drug Metformin Linked to Lower Lung Cancer Rate in MiceCategory: Health NewsCreated: 9/1/2010 2:10:00 PMLast Editorial Review: 9/2/2010 (Source: MedicineNet Cancer General)
Weight Loss Pill Meridia Raises Heart Attack, Stroke Risks
Title: Weight Loss Pill Meridia Raises Heart Attack, Stroke RisksCategory: Health NewsCreated: 9/2/2010 11:01:00 AMLast Editorial Review: 9/2/2010 11:01:05 AM (Source: MedicineNet Diabetes General)
Sleep-Deprived Teens Eat More Fat, Study Finds
Title: Sleep-Deprived Teens Eat More Fat, Study FindsCategory: Health NewsCreated: 9/1/2010 10:10:00 AMLast Editorial Review: 9/2/2010 (Source: MedicineNet Diabetes General)
Immune System Research Sees Many Similarities Among People
Title: Immune System Research Sees Many Similarities Among PeopleCategory: Health NewsCreated: 9/1/2010 2:10:00 PMLast Editorial Review: 9/2/2010 (Source: MedicineNet Diabetes General)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Register for <b><a href="http://www.medmatcha.com" target ="_self">MedMatcha, MedWorm's medical advertising network</a></b>, and receive $5 free advertising.</p></div>
Diabetes Drug Metformin Linked to Lower Lung Cancer Rate in Mice
Title: Diabetes Drug Metformin Linked to Lower Lung Cancer Rate in MiceCategory: Health NewsCreated: 9/1/2010 2:10:00 PMLast Editorial Review: 9/2/2010 (Source: MedicineNet Diabetes General)
Diabetes Drug Metformin Linked to Lower Lung Cancer Rate in Mice
Title: Diabetes Drug Metformin Linked to Lower Lung Cancer Rate in MiceCategory: Health NewsCreated: 9/1/2010 2:10:00 PMLast Editorial Review: 9/2/2010 (Source: MedicineNet Senior Health General)
Angola: Diabetes Association Set Up in Huíla
An Angolan Diabetes Association (ASDA) was set up on Tuesday, in Lubango City, in the southern Huíla Province, aimed at warning, training and educating sufferers of this disease on how to fight against diabetes. (Source: AllAfrica News: Health and Medicine)
Human mesenchymal stem cell proliferation and osteogenic differentiation during long-term ex vivo cultivation is not age dependent
In this study we investigated the influence of donor age on proliferation and osteogenic differentiation in long-term ex vivo cultures of primary human MSCs from patients in different age groups. Fifteen patients (8 men/7 women) comprised three age groups: (I) &lt;50&nbsp;years, (II) 50?65&nbsp;years, and (III) &gt;65&nbsp;years. MSCs harvested from bone marrow derived from routine surgical procedures were isolated and cultured in standard medium over eight passages. Osteogenic differentiation was induced by dexamethasone (10&nbsp;nM), ascorbic acid (300&nbsp;?M), and ?-glycerophosphate (3.5&nbsp;mM). Osteogenic differentiation capacity of MSCs was quantified by alkaline phosphatase (ALP) activity, fluorescence-activated cell sorting (FACS) analysis of the surface markers CD9, CD...
Interferon-gamma-inducible kynurenines/pteridines inflammation cascade: implications for aging and aging-associated psychiatric and medical disorders
Abstract&nbsp;&nbsp;This review of literature and our data suggests that up-regulated production of interferon-gamma (IFNG) in periphery and brain triggers a merger of tryptophan (TRY)?kynurenine (KYN) and guanine?tetrahydrobiopterin (BH4) metabolic pathways into inflammation cascade involved in aging and aging-associated medical and psychiatric disorders (AAMPD) (metabolic syndrome, depression, vascular cognitive impairment). IFNG-inducible KYN/pteridines inflammation cascade is characterized by up-regulation of nitric oxide synthase (NOS) activity (induced by KYN) and decreased formation of NOS cofactor, BH4, that results in uncoupling of NOS that shifting arginine from NO to superoxide anion production. Superoxide anion and free radicals among KYN derivatives trigger phospholi...<div id="medworm"><p><b><i>MedWorm Message:</i></b> Register for <b><a href="http://www.medmatcha.com" target ="_self">MedMatcha, MedWorm's medical advertising network</a></b>, and receive $5 free advertising.</p></div>
Amaurosis after spine surgery: survey of the literature and discussion of one case
Abstract&nbsp;&nbsp;Postoperative vision loss (POVL) associated with spine surgery is a well known, albeit very rare complication. POVL incidence after spinal surgery ranges from 0.028 to 0.2%; however, due to the increase in number and duration of annual complex spinal operations, the incidence may increase. Origin and pathogenesis of POVL remain frequently unknown. A 73-year-old patient presented with lumbar disc herniation with associated neurological deficits after conservative pre-treatment at a peripheral hospital. Known comorbidities included arterial hypertension, moderate arterial sclerosis, diabetes mellitus type 2, mildly elevated blood lipids and treated prostate gland cancer. During lumbar spine surgery in modified prone position the patient presented with an acute episo...
Biochemistry of the Anterior, Medial, and Posterior Genioglossus in the Aged Rat
We examined the myosin heavy chain (MHC) composition of anterior, medial, and posterior sections of the genioglossus muscle (GG) in ten old male Fischer 344/Brown Norway rats and compared findings to previously reported data from young adult male rats. Significant differences (p&nbsp;&lt;&nbsp;0.01) between young adult and old rats were found in the distribution of MHC isoforms along the anteroposterior axis of the muscle. In the anterior, medial, and posterior regions, there was a significantly smaller proportion of type IIb MHC in the old rat GG muscles, while the proportion of type IIx MHC was significantly greater. In the medial region, the proportion of type I MHC was found to be significantly greater in the old rats. Thus, we found a shift to more slowly contracting muscle fibe...
The effect of acute effort on EEG in healthy young and elderly subjects
Abstract&nbsp;&nbsp;The effects of physical exercise on mental health have been extensively investigated, mainly in older people. Recent studies have looked into the acute effect of exercise on the brain using standardized low-resolution brain electromagnetic tomography (sLORETA). We assessed EEG power and mood changes after 20&nbsp;min of aerobic exercise in elderly (N&nbsp;=&nbsp;10) and young (N&nbsp;=&nbsp;19) healthy individuals. Both groups showed improvement in total mood disturbance (TMD) post exercise (young: P&nbsp;=&nbsp;0.03; elderly: P&nbsp;=&nbsp;0.02). Only the young group showed significant improvement in anger (P&nbsp;=&nbsp;0.05) and vigor (P&nbsp;=&nbsp;0.006). Comparison pre versus post-exercise for each group separately revealed significant changes in the young group...
Influence of Biopsychosocial Factors on the Survival of the Elderly in Northeast Brazil&#8212;A Prospective Study
Discussion. The risk factors found in the study can be interpreted as the primary predictors for death among elderly members of the community. (Source: Current Gerontology and Geriatrics Research)
Association analysis of SLC30A8 rs13266634 and rs16889462 polymorphisms with type 2 diabetes mellitus and repaglinide response in Chinese patients
Conclusions&nbsp;&nbsp; SLC30A8 rs13266634 and rs16889462 polymorphisms were associated with repaglinide therapeutic efficacy in Chinese T2DM patients. Content Type Journal ArticleDOI 10.1007/s00228-010-0882-6Authors Qiong Huang, Institute of Clinical Pharmacology, Hunan Key Laboratory of Pharmacogenetics, Central South University, Changsha, Hunan 410078, People?s Republic of ChinaJi-Ye Yin, Institute of Clinical Pharmacology, Hunan Key Laboratory of Pharmacogenetics, Central South University, Changsha, Hunan 410078, People?s Republic of ChinaXing-Ping Dai, Institute of Clinical Pharmacology, Hunan Key Laboratory of Pharmacogenetics, Central South University, Changsha, Hunan 410078, People?s Republic of ChinaJing Wu, Department of Endocrinology, The XiangYa Hospital, Cent...<div id="medworm"><p><b><i>MedWorm Message:</i></b> Register for <b><a href="http://www.medmatcha.com" target ="_self">MedMatcha, MedWorm's medical advertising network</a></b>, and receive $5 free advertising.</p></div>
Prolapse surgery in women of 80 years and older using the Prolift? technique
Conclusions&nbsp;&nbsp;Treatment of advanced prolapse using Prolift? in very elderly women is a feasible, safe, and effective surgical option, preserving a functional vagina. Thus, this may represent one alternative to colpocleisis. Content Type Journal ArticleDOI 10.1007/s00192-010-1217-yAuthors Boris Gabriel, Clinique de chirurgie gynécologique, Hopital Jeanne de Flandre, Centre Hospitalier Regional Universitaire de Lille, Université Lille Nord de France, 2, av. Oscar Lambret, 59037 Lille Cedex, FranceChrystèle Rubod, Clinique de chirurgie gynécologique, Hopital Jeanne de Flandre, Centre Hospitalier Regional Universitaire de Lille, Université Lille Nord de France, 2, av. Oscar Lambret, 59037 Lille Cedex, FranceLuis Gordillo Córdova, Clinique de chirurgie gynécologiqu...
Screening for gestational diabetes mellitus: cost?utility of different screening strategies based on a woman?s individual risk of disease
Conclusions/interpretation&nbsp;&nbsp;Screening for gestational diabetes can be cost-effective. The best strategy is dependent on the underlying risk of each individual and the acceptability of the tests used. The current study suggests that if a woman?s individual risk of gestational diabetes could be accurately predicted, then healthcare resource allocation could be improved by providing an individualised screening strategy. Content Type Journal ArticleDOI 10.1007/s00125-010-1881-yAuthors J. A. Round, Academic Unit of Health Economics, Institute of Health Sciences, University of Leeds, Leeds, UKP. Jacklin, National Collaborating Centre for Women?s and Children?s Health, London, UKR. B. Fraser, Academic Unit of Reproductive and Developmental Medicine, University of She...
ACE I-ARB combination therapy not detrimental to severely hypertensive diabetics
Australian researchers suggest that combined ACE inhibitor and angiotensin receptor blocker antihypertensive therapy does not produce more renal damage than monotherapy with either drug in diabetes patients with severe hypertension. (Source: MedWire News - Diabetes)
Increased risk of death in men with insomnia and a short sleep duration
Men with chronic insomnia who slept for less than six hours were four times more likely to die during the 14-year follow-up period, according to a new study. Results were adjusted for potential confounders such as body mass index, smoking status, depression and obstructive sleep apnea. Further adjustments for hypertension and diabetes had little effect on the elevated mortality risk. No significant mortality risk was found in women with insomnia and a short sleep duration of less than six hours. (Source: ScienceDaily Headlines)
Bigger role for pharmacists planned
Pharmacies in Scotland will provide a five-star chronic medication service for patients with conditions like diabetes and high blood pressure (Source: Pharmacy Europe)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Register for <b><a href="http://www.medmatcha.com" target ="_self">MedMatcha, MedWorm's medical advertising network</a></b>, and receive $5 free advertising.</p></div>
Potential remains for PPAR-targeted drugs
Nature Reviews Drug Discovery 9, 668 (2010). doi:10.1038/nrd3271 Author: Dan Jones The controversy over the diabetes drug rosiglitazone (Avandia; GlaxoSmithKline), a peroxisome proliferator-activated receptor-? agonist, has undermined confidence in developing drugs that target this family of nuclear receptors, but some companies still see promise in the field. (Source: Nature Reviews Drug Discovery)
Deal watch: Metabolex and Sanofi?Aventis partner on GPCR agonists for type 2 diabetes
Nature Reviews Drug Discovery 9, 670 (2010). doi:10.1038/nrd3255 Metabolex has entered into an agreement with Sanofi?Aventis for the development of small molecules that target G protein-coupled receptor 119 (GPR119), the most advanced of which is in a Phase II trial for the treatment of type 2 diabetes (T2D). Metabolex will receive upfront and (Source: Nature Reviews Drug Discovery)
Age as a Risk Factor for Stroke in Atrial Fibrillation Patients: Implications for Thromboprophylaxis
The prevalence of atrial fibrillation (AF) is related to age and is projected to rise exponentially as the population ages and the prevalence of cardiovascular risk factors increases. The risk of ischemic stroke is significantly increased in AF patients, and there is evidence of a graded increased risk of stroke associated with advancing age. Oral anticoagulation (OAC) is far more effective than antiplatelet agents at reducing stroke risk in patients with AF. Therefore, increasing numbers of elderly patients are candidates for, and could benefit from, the use of anticoagulants. However, elderly people with AF are less likely to receive OAC therapy. This is mainly due to concerns about a higher risk of OAC-associated hemorrhage in the elderly population. Until recently, older patients were ...
Children who eat vended snack foods face chronic health problems, poor diet
(University of Michigan Health System) School children who consume foods purchased in vending machines are more likely to develop poor diet quality -- and that may be associated with being overweight, obese or at risk for chronic health problems such as diabetes and coronary artery disease, according to research from the University of Michigan Medical School. (Source: EurekAlert! - Biology)
Variation in Quality of Care Indicators for Diabetes in a National Sample of Veterans and Non-Veterans
Diabetes Technology & Therapeutics , Vol. 0, No. 0. (Source: Diabetes Technology)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Register for <b><a href="http://www.medmatcha.com" target ="_self">MedMatcha, MedWorm's medical advertising network</a></b>, and receive $5 free advertising.</p></div>
Most diabetics need better BP control to reach targets
Belgian researchers report that only 16% of patients with Type 2 diabetes achieve the target blood pressure of 130/80 mmHg recommended by American and European regulatory bodies such as the European Society of Hypertension. (Source: MedWire News - Diabetes)
Diabetes drug can reduce risk of cancer, researchers find
Metformin reduced the development of lung tumors in mice by more than 70%. Clinical trials on humans for lung, breast and prostate cancer are being organized.A growing body of evidence suggests that the widely used diabetes drug metformin can reduce the risk of cancer, researchers said Wednesday. (Source: Los Angeles Times - Science)
Diabetes drug can reduce risk of cancer, researchers find
Metformin reduced the development of lung tumors in mice by more than 70%. Clinical trials on humans for lung, breast and prostate cancer are being organized.A growing body of evidence suggests that the widely used diabetes drug metformin can reduce the risk of cancer, researchers said Wednesday. (Source: L.A. Times - Health)
Sphingolipids as Signaling and Regulatory Molecules
series:Advances in Experimental Medicine and BiologyThis book attempts to analyze the latest discoveries in sphingolipid biology and how the alteration of their metabolism leads to altered signaling events and to the development of pathobiological disorders, such as cancer, cardiovascular diseases, asthma, diabetes, inflammation and infectious diseases. (Source: Springer Biomedical Sciences titles)
Elderly broken hip care concerns
One in five elderly people with broken hips do not get surgery quickly enough, a survey shows. (Source: BBC News | Health | UK Edition)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Register for <b><a href="http://www.medmatcha.com" target ="_self">MedMatcha, MedWorm's medical advertising network</a></b>, and receive $5 free advertising.</p></div>
Prevalence of erectile dysfunction among Chinese men with type 2 diabetes mellitus
Authors: G Yang, C Pan & J Lu (Source: International Journal of Impotence Research)
Epidemiological and economic burden of metabolic syndrome and its consequences in patients with hypertension in Germany, Spain and Italy; a prevalence-based model.
Conclusion: The presence of metabolic syndrome in patients with hypertension significantly inflates economic burden and costs are likely to increase in the future due to an aging population and an increase in the prevalence of components of metabolic syndrome. (Source: BMC Public Health - Latest articles)
Increased levels of CRP and MCP-1 are associated with previously unknown abnormal glucose regulation in patients with acute STEMI: a cohort study.
Conclusion: Elevated levels of CRP and MCP-1 measured in patients early after an acute STEMI were associated with abnormal glucose regulation classified by an OGTT at three-month follow-up. No significant associations were observed between inflammatory markers and hyperglycaemia measured during the acute STEMI. (Source: Cardiovascular Diabetology)
Survey on access to insulin pump therapy
Source: Medical Technology Group (MTG), Area: News The Medical Technology Group (MTG), a coalition of patient groups, research charities and medical device manufacturers, has published the findings of its survey of 152 PCTs about access to insulin pump therapy, which confirmed that overall uptake and utilisation for insulin pump therapy remains extremely low. &nbsp; The survey found that: &nbsp; .&nbsp;The average rate of insulin pump provision for people with type 1 diabetes is 3.9% compared to the 12% benchmark recommended by NICE. &nbsp; .&nbsp;Two PCTs gave information which suggests they are providing insulin pumps in line with the NICE benchmark. &nbsp; .&nbsp;Five out of 113 PCTs have a strategy in place to implement NICE guidance on insulin pumps in line with their...

avoid is a potato, as it has a high glycemic index. Other fruits and vegetables, however, are preferable than white rice, white bread, corn flakes and anything made with white refined sugar or flour.

Other good glycemic foods include wholegrain breads and pastas. If you or a loved one has Type I or Type II diabetes, you should switch to whole grain breads and pastas made from wheat flour. This can be tremendously helpful to anyone who wants to manage their glycemia as well as anyone who wants to follow such low carb diets. Basmati rice is also considered one of the good glycemic foods.

Often, it is not a matter of eliminating carbohydrates when one is using diet to control their diabetes, but understanding which carbohydrates rate high on the glycemic index. is a disease that can be controlled by proper diet, monitoring one's blood sugar and following doctor's orders as far as medication.

Diabetes can be controlled by a healthy diet. By learning about the Glycemic Index, one can empower themselves to learn which foods should be avoided and which foods can be beneficial to their health. All individuals can benefit from the Glycemic Index, but this information is particularly invaluable to someone with diabetes.