Type 1
Type 2
Non-insulin Dependent Diabetes Mellitus
Type Ii Diabetes
Sugar Diabetes
Diabetes Mellitus
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  Increasing Soda Consumption Fuels Rise in Diabetes, Heart Disease (HealthDay)
HealthDay - FRIDAY, March 5 (HealthDay News) --Increasing consumption of sugary soft drinks contributed to 130,000 new cases of diabetes, 14,000 new cases of heart disease and 50,000 more life-years burdened with heart disease in the last decade, a new U.S. study finds.
Processed Meat May Harm the Heart (HealthDay)
HealthDay - FRIDAY, March 5 (HealthDay News) -- Conventional wisdom has dictated that fat from red meat is a risk factor for heart disease, but a new analysis from Harvard researchers finds it's eating processed meat -- not unprocessed red meat -- that increases the risk for heart disease and even diabetes.
Bugs in the gut can cause obesity: study (AFP)
AFP - The bugs that help digest food may also cause the body to pack on the pounds if they are not properly regulated, a new study has found.
Bugs in the gut can cause obesity: study (AFP)
AFP - The bugs that help digest food may also cause the body to pack on the pounds if they are not properly regulated, a new study has found.
Lunchtime coffee break best for fighting diabetes (Reuters)
Reuters - Drinking coffee cuts diabetes risk, new research confirms, but you may need to enjoy your java with lunch if you want to get any benefit.
Whole Grains Take a Bite Out of Type 2 Diabetes Risk (HealthDay)
HealthDay - WEDNESDAY, March 3 (HealthDay News) -- Brown rice is better than white rice at reducing the risk of type 2 diabetes, but whole grains are the most effective at lowering the risk, study findings show.
A1c diabetes test is a better indicator of risk (Reuters)
Reuters - A test that shows blood sugar levels over a span of several weeks is not only the best way to diagnose diabetes but also may be better at identifying who is at risk of getting diabetes than standard blood sugar tests, researchers said on Wednesday.
Newer Blood Test Predicts Diabetes, Heart Disease (HealthDay)
HealthDay - WEDNESDAY, March 3 (HealthDay News) -- The newer hemoglobin A1C test predicts diabetes as well as the traditional fasting blood sugar test, but it beats that old standard in predicting a patient's future risk of heart disease and stroke, new research shows.
Having Prediabetes May Not Kick-Start Prevention Efforts (HealthDay)
HealthDay - TUESDAY, March 2 (HealthDay News) -- Knowing you're on the cusp of developing diabetes apparently isn't enough to make most people take steps to prevent it.
Scientists try to break fat-and-disease link (AP)
AP - What if you could be fat but avoid heart disease or diabetes? Scientists trying to break the fat-and-disease link increasingly say inflammation is the key.
 
type 1 guide
 

Treat Acne With A Low Glycemic Diet
By Simon Evans

Do you or your kids have acne problems? The majority of adolescents and a small number of adults deal with significant facial blemishes. I remember going through a bought in my early 20's. It can be difficult for teens and young adults entering the dating years if they are always worrying about how they look. If your kids are struggling with acne, you may be able to help them out now, while setting them up for a healthier future at the same time.

An interesting article published recently in the American Journal of Clinical Nutrition described improvements in teenage acne using a low glycemic diet. I have written many articles before on the glycemic index. Typically, I have focused on the benefit of a low glycemic diet for weight loss, chronic disease prevention and energy level increases. However, this new study suggests that it is also beneficial for acne therapy.

In the study, the investigators recruited 15 – 25 year old boys/men with acne problems. They instructed half of them to eat low glycemic foods and the other half continued eating mostly as they had been. They made sure that the change in diet did not differ from the amount of calories they were already eating; they didn't want weight loss to be a factor. The investigators also made sure that the participants didn't now that they were being checked for acne treatments – to avoid a placebo effect. Instead, they thought it was a test for monitoring protein to carbohydrate ratios.

After 12 weeks of dietary intervention the low glycemic diet group had significant improvements in their acne compared to before they started on the diet and compared to the control group. This is another ingenious example of how to use lifestyle choices to address problems that we often resort to drug treatments for.

The cause of acne is still mostly unknown. Way back in the 1930's doctors believed that it had something to do with blood sugar, but this fell out of favor with some research in the late 1960's. More recently, that later work has been called into question and the concept that acne has something to do with carbohydrate metabolism and blood sugar has gained ground again. This new study suggests that the

Insulin Glargine QD Equivalent to Insulin Detemir BID for Type 2 Diabetics
Once-daily insulin glargine and twice-daily insulin detemir provided similar glycemic control for insulin-na?ve type 2 diabetics in a noninferiority trial. Reuters Health Information (Source: Medscape Medical News Headlines)
The Role of Exercise-Induced Myokines in Muscle Homeostasis and the Defense against Chronic Diseases
In conclusion, exercise-induced myokines appear to be involved in mediating both systemic as well as local anti-inflammatory effects. (Source: Journal of Biomedicine and Biotechnology)
Bezafibrate and serum amyloid A-low-density lipoprotein complex in patients with type 2 diabetes mellitus and hypertriglyceridemia.
Authors: Kotani K, Satoh N, Yamada T PMID: 20206863 [PubMed - as supplied by publisher] (Source: European Journal of Internal Medicine)
Clinical factors that influence the cardiovascular morbidity in patients with type II Diabetes Mellitus.
Authors: Kyriazis I, Mendrinos D, Saridi M PMID: 20206869 [PubMed - as supplied by publisher] (Source: European Journal of Internal Medicine)
Children?s launches new stem cell Web site
By Jonathan Kraft, president of The Kraft Group and New England Patriots As a long-time supporter of stem cell research, I’m proud to announce the launch of a new Children’s Hospital Boston Web site that we hope will demystify the science of stem cells and answer some of the public’s questions about them. For the past three and a half years, my wife, Patti, and I have served as co-chairs of Children’s Hospital Boston?s Stem Cell Task Force because we believe that stem cells hold incredible promise for the future of health care. During this time I?ve gotten to know Len Zon and George Daley, the two physician-scientists who head up the hospital?s Stem Cell Research Program, and I believe that the work they are doing will revolutionize health care.They?ve expl...
Bilateral carpal tunnel syndrome in a child with type 1 diabetes mellitus
Duru Nilgun Selcuk, Acar Hurtan, Ayta Semih, Elevli MuratNeurology India 2010 58(1):136-137 (Source: Neurology India)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Get the very latest Swine Flu news via the MedWorm <b><a href="http://www.medworm.com/rss/search.php?qu=%2Bswine+%2B%28influenza+flu%29&t=Swine+Flu&f=infectiousdiseases&r=Any&o=d" target ="_self">Swine Flu RSS news feed</a></b> - updated hourly from thousands of authoritative health and news sources.</p></div>
High basic fibroblast growth factor increases CHD risk in Type 2 diabetics
Elevated plasma basic fibroblast growth factor immunoreactivity increases coronary heart disease risk in men with Type 2 diabetes, report researchers. (Source: MedWire News - Diabetes)
Licorice ? or more?
Exp Clin Endocrinol DiabetesDOI: 10.1055/s-0029-1224123AbstractA 57 yr old man presented to endocrinology clinic with a six year history of poorly controlled hypertension which was treated with Metoprolol 200&#8201;mg/day and Enalapril 20&#8201;mg/day. He was asymptomatic but incidentally hypokalaemia was detected while having cholecystectomy, two years prior to his clinic appointment. He had never been on diuretics or laxatives. He was started on potassium supplements (120&#8201;mmol/d) and advised to increase dietary potassium by the surgical team. A detailed personal history revealed ingestion of 300&#8211;500&#8201;g licorice per day. Physical examination was unremarkable apart from increased blood pressure of 180/105&#8201;mmHg. Following the initial visit, his serum electrolyes (K+3....
Lipid Peroxidation and Antioxidant System in Rats Acutely Treated with Acetone
The objective of the present study was to determine the effects of acute treatment (AT) with acetone on the oxidative and metabolic status of rats. The AT group (n=16) was treated by gavage with a single administration of 7.0&#8201;g acetone/kg body weight at a concentration of 25% (m/v). Eight rats were euthanized 6&#8201;h later (AT6) and eight 24&#8201;h later (AT24). Acetone levels were determined in blood and urine and oxidative parameters were analyzed by determining thiobarbituric acid reactive species (TBARS, indicators of lipid peroxidation) and reduced glutathione (GSH) and vitamin E as antioxidant parameters. Serum glucose, blood cholesterol and triglycerieds and hepatic fat were also determined. The results indicated a significant difference in the hepatic oxidative parameters,...
Genetic Associations of IL1RN Polymorphisms with Metabolic Syndrome in a Korean Population
Exp Clin Endocrinol DiabetesDOI: 10.1055/s-0030-1248288AbstractMetabolic syndrome (MetS) is rapidly growing into one of the major public health issues worldwide. Interleukin 1 receptor antagonist (IL1Ra) functions as a competitor of proinflammatory cytokines and has an important role in metabolic functions, including insulin secretion. To identify the relationship between the interleukin 1 receptor antagonist gene and MetS, we genotyped nine single nucleotide polymorphisms (SNPs) in the gene using direct sequencing in 66 MetS patients and 346 normal subjects in the Korean population. Among the nine polymorphisms, after adjusting for age and sex, rs928940 (G&gt;T) showed a significant association with MetS in the codominant ( 0.023) and recessive models ( 0.011). Also, rs315952 (C&gt;T) exh...
Type 2 diabetes mellitus: A risk factor for
Conclusion: Diabetic patients are more prone and at risk to acquire H. Pylori infection. Therefore proper monitoring of blood glucose level and screening for H. pylori infection are effective preventive measures for this life threatening infection. (Source: International Journal of Diabetes in Developing Countries)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Get the very latest Swine Flu news via the MedWorm <b><a href="http://www.medworm.com/rss/search.php?qu=%2Bswine+%2B%28influenza+flu%29&t=Swine+Flu&f=infectiousdiseases&r=Any&o=d" target ="_self">Swine Flu RSS news feed</a></b> - updated hourly from thousands of authoritative health and news sources.</p></div>
Hypoglycemic effect of aqueous extract of
Conclusion: The aqueous extract of Trichosanthes dioica has antihyperglycemic action. (Source: International Journal of Diabetes in Developing Countries)
Free radical scavenging activity of
Rathod N R, Raghuveer I, Chitme H R, Chandra RIndian Journal of Pharmaceutical Sciences 2009 71(6):615-621Swarnabhasma , an Ayurvedic preparation containing Calotropis gigantea R. Br. (Asclepiadaceae) is extensively used by Ayurvedic physicians for treatment of diabetes mellitus, bronchial asthma, rheumatoid arthritis and nervous disorders. In the present study, we report the effect of chloroform extracts of Calotropis gigantea leaf and flower on free radical scavenging activity, and lipid profile in streptozotozin-induced diabetic rats. The lipid peroxidation, superoxide dismutase, and catalase were measured in liver homogenate and serum glutamic pyruvic transaminase, serum glutamic oxaloacetic transaminase, alkaline phosphatase, lipid profile were measured in blood serum. Administration ...
High basic fibroblast growth factor increases CHD risk in Type 2 diabetics
Elevated plasma basic fibroblast growth factor immunoreactivity increases coronary heart disease risk in men with Type 2 diabetes, report researchers. (Source: MedWire News - Heart Failure)
Blunting of the Heart Rate Response to Adenosine and Regadenoson in Relation to Hyperglycemia and the Metabolic Syndrome
Adenosine and regadenoson cause an increase in heart rate (HR) during myocardial perfusion imaging (MPI). It has been shown that patients with diabetes mellitus have a blunted HR response due to cardiac autonomic dysfunction. It is not known whether the HR response is related to hyperglycemia and the metabolic syndrome (MS). HR changes were assessed in 2,000 patients (643 with diabetes mellitus [DM]) in the Adenoscan Versus Regadenoson Comparative Evaluation for Myocardial Perfusion Imaging (ADVANCE MPI 1 and ADVANCE MPI 2) trials in relation to MS status and blood sugar level on the day of MPI. The HR response was lower in patients with MS (32.43 ± 0.52% vs 36.15 ± 0.71%, p (Source: The American Journal of Cardiology)
Prognostic Value of an Exaggerated Exercise Blood Pressure Response in Patients With Diabetes Mellitus and Known or Suspected Coronary Artery Disease
The prognostic value of an exaggerated exercise systolic blood pressure response (EESBPR) remains controversial. Our aim was to assess whether an EESBPR is associated with the long-term outcome in patients with diabetes mellitus and known or suspected coronary artery disease (CAD). From an initial population of 22,262 patients with known or suspected CAD who underwent treadmill exercise electrocardiography or exercise echocardiography at our institution, 2,591 patients with a history of diabetes mellitus were selected for the present study. EESBPR was defined as systolic blood pressure >220 mm Hg during exercise. The end points were all-cause mortality and hard events (ie, death or myocardial infarction). A total of 236 patients (9.1%) developed an EESBPR during the tests. During a mean fo...<div id="medworm"><p><b><i>MedWorm Message:</i></b> Get the very latest Swine Flu news via the MedWorm <b><a href="http://www.medworm.com/rss/search.php?qu=%2Bswine+%2B%28influenza+flu%29&t=Swine+Flu&f=infectiousdiseases&r=Any&o=d" target ="_self">Swine Flu RSS news feed</a></b> - updated hourly from thousands of authoritative health and news sources.</p></div>
Does Getting Fat Protect against Fat?
Everyone knows that obesity is bad for your health. Packing on the pounds, we&rsquo;re told, leads to all sorts of medical problems: high cholesterol, insulin resistance, greater risk of diabetes and heart disease. But researchers at the University of Texas Southwestern Medical Center see things a little differently. In a paper in the journal Trends in Endocrinology and Metabolism [see http://bit.ly/bKaP33 ], they argue that being fat can actually protect us from these disorders. [More] (Source: Scientific American - Official RSS Feed)
Macular ischaemia after intravitreal bevacizumab injection in patients with central retinal vein occlusion and a history of diabetes and vascular disease
(Source: British Journal of Ophthalmology)
Taxing junk food improves health outcomes, study finds
(Source: BMJ Online First)
Obesity As Protection Against Metabolic Syndrome, Not Its Cause
The collection of symptoms that is the metabolic syndrome - insulin resistance, high cholesterol, fatty liver, and a greater risk for diabetes, heart disease, and stroke - are all related to obesity, but, according to a review in the March 9th issue of the Cell Press publication Trends in Endocrinology and Metabolism, not in the way you probably think they are... (Source: Cholesterol News From Medical News Today)
Obesity As Protection Against Metabolic Syndrome, Not Its Cause
The collection of symptoms that is the metabolic syndrome - insulin resistance, high cholesterol, fatty liver, and a greater risk for diabetes, heart disease, and stroke - are all related to obesity, but, according to a review in the March 9th issue of the Cell Press publication Trends in Endocrinology and Metabolism, not in the way you probably think they are. In fact, says Roger Unger of the University of Texas Southwestern at Dallas, obesity is the body's way of storing lipids where they belong, in fat tissue, in an effort to protect our other organs from lipids' toxic effects... (Source: Health News from Medical News Today)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Get the very latest Swine Flu news via the MedWorm <b><a href="http://www.medworm.com/rss/search.php?qu=%2Bswine+%2B%28influenza+flu%29&t=Swine+Flu&f=infectiousdiseases&r=Any&o=d" target ="_self">Swine Flu RSS news feed</a></b> - updated hourly from thousands of authoritative health and news sources.</p></div>
Obesity as protection against metabolic syndrome, not its cause
The collection of symptoms that is the metabolic syndrome -- insulin resistance, high cholesterol, fatty liver, and a greater risk for diabetes, heart disease, and stroke -- are all related to obesity, but, according to a new review not in the way you probably think they are. (Source: ScienceDaily Headlines)
Higher Fast Food Prices Lead To Lower Weight, Diabetes Risk
A new study that followed participants for 20 years shows both weight and risk for diabetes decreased for people in communities where fast food prices increased. The University of North Carolina at Chapel Hill study, published in the March 8, 2010, issue of Archives of Internal Medicine, also showed the reverse when fast food prices fell, then consumption, weight and diabetes risks rose... (Source: Health News from Medical News Today)
Higher Fast Food Prices Lead To Lower Weight, Diabetes Risk
A new study that followed participants for 20 years shows both weight and risk for diabetes decreased for people in communities where fast food prices increased. The University of North Carolina at Chapel Hill study, published in the March 8, 2010, issue of Archives of Internal Medicine, also showed the reverse when fast food prices fell, then consumption, weight and diabetes risks rose... (Source: Diabetes News From Medical News Today)
Eye Disease Linked To Weakened Brain Power In People With Diabetes
Diabetic retinopathy, the leading cause of blindness in the UK's working-age population, could be associated with poorer memory and diminished brain power in people with Type 2 diabetes, according to new research¹ announced this week at leading health charity Diabetes UK's Annual Professional Conference. The study looked at 1,066 people with Type 2 diabetes aged between 60 and 75 years old. Participants completed seven tests looking at memory, logic and concentration to establish their level of brain function... (Source: Health News from Medical News Today)
Is There A Link Between Drinking Too Many Sugary Drinks And Diabetes?
A new study claims that having sugary drinks every day could put people at a greater risk of developing Type 2 diabetes and heart disease. American researchers found that the excessive consumption of sugary drinks, which can contain up to 200 calories each, contributed to 130,000 cases of Type 2 diabetes and 14,000 cases of heart disease between 1990 and 2000 in the USA. The researchers also concluded that sugary drinks are fuelling the obesity epidemic... (Source: Health News from Medical News Today)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Get the very latest Swine Flu news via the MedWorm <b><a href="http://www.medworm.com/rss/search.php?qu=%2Bswine+%2B%28influenza+flu%29&t=Swine+Flu&f=infectiousdiseases&r=Any&o=d" target ="_self">Swine Flu RSS news feed</a></b> - updated hourly from thousands of authoritative health and news sources.</p></div>
Eye Disease Linked To Weakened Brain Power In People With Diabetes
Diabetic retinopathy, the leading cause of blindness in the UK's working-age population, could be associated with poorer memory and diminished brain power in people with Type 2 diabetes, according to new research¹ announced this week at leading health charity Diabetes UK's Annual Professional Conference. The study looked at 1,066 people with Type 2 diabetes aged between 60 and 75 years old... (Source: Diabetes News From Medical News Today)
Is There A Link Between Drinking Too Many Sugary Drinks And Diabetes?
A new study claims that having sugary drinks every day could put people at a greater risk of developing Type 2 diabetes and heart disease. American researchers found that the excessive consumption of sugary drinks, which can contain up to 200 calories each, contributed to 130,000 cases of Type 2 diabetes and 14,000 cases of heart disease between 1990 and 2000 in the USA... (Source: Diabetes News From Medical News Today)
Surprising findings about Hepatitis C and insulin resistance
(Research Australia) We have known for several years that Hepatitis C, a common cause of liver cirrhosis and cancer, also makes people three to four times more likely to develop Type 2 diabetes. In studying the insulin resistance of 29 people with Hepatitis C, Australian researchers have confirmed that they have high insulin resistance, a precursor to diabetes. However, almost all insulin resistance was in muscle, with little or none in the liver, a very surprising finding given that Hepatitis C is a liver disease. (Source: EurekAlert! - Medicine and Health)
Starting treatment early doubles chance of success for people with diabetes
(GolinHarris International) The sooner people with diabetes start taking metformin, the longer the drug remains effective, according to a Kaiser Permanente study published in the March issue of Diabetes Care, a journal of the American Diabetes Association. (Source: EurekAlert! - Medicine and Health)
Surprising findings about Hepatitis C and insulin resistance
Scientists have known for several years that Hepatitis C, a common cause of liver cirrhosis and cancer, also makes people three to four times more likely to develop Type 2 diabetes. In studying the insulin resistance of 29 people with Hepatitis C, Australian researchers have confirmed that they have high insulin resistance, a precursor to diabetes. However, almost all insulin resistance was in muscle, with little or none in the liver, a very surprising finding given that Hepatitis C is a liver disease. (Source: ScienceDaily Headlines)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Get the very latest Swine Flu news via the MedWorm <b><a href="http://www.medworm.com/rss/search.php?qu=%2Bswine+%2B%28influenza+flu%29&t=Swine+Flu&f=infectiousdiseases&r=Any&o=d" target ="_self">Swine Flu RSS news feed</a></b> - updated hourly from thousands of authoritative health and news sources.</p></div>
Starting treatment early doubles chance of success for people with diabetes
The sooner people with diabetes start taking metformin, the longer the drug remains effective, according to a new study. (Source: ScienceDaily Headlines)
Soft Drink and Juice Consumption and Risk of Physician-diagnosed Incident Type 2 Diabetes: The Singapore Chinese Health Study
Soft drinks and other sweetened beverages may contribute to risk of type 2 diabetes and obesity. However, research has not addressed higher risk and Asian populations. The authors examined the association between soft drinks and juice and the risk of type 2 diabetes among Chinese Singaporeans enrolled in a prospective cohort study of 43,580 participants aged 45&ndash;74 years and free of diabetes and other chronic diseases at baseline. The incidence of physician-diagnosed type 2 diabetes was assessed by interview and validated; 2,273 participants developed diabetes during follow-up. After adjustment for potential lifestyle and dietary confounders, participants consuming &ge;2 soft drinks per week had a relative risk of type 2 diabetes of 1.42 (95% confidence interval (CI): 1.25, 1.62) comp...
The Association Between the Peroxisome Proliferator-Activated Receptor-{gamma}2 (PPARG2) Pro12Ala Gene Variant and Type 2 Diabetes Mellitus: A HuGE Review and Meta-Analysis
The peroxisome proliferator-activated receptor- gene (PPARG) has been implicated in the etiology of type 2 diabetes mellitus and has been investigated in numerous epidemiologic studies. In this Human Genome Epidemiology review, the authors assessed this relation in an updated meta-analysis of 60 association studies. Electronic literature searches were conducted on September 14, 2009. Population-based cohort, case-control, cross-sectional, or genome-wide association studies reporting associations between the PPARG Pro12Ala gene variant (rs1801282) and type 2 diabetes were included. An updated literature-based meta-analysis involving 32,849 type 2 diabetes cases and 47,456 controls in relation to the PPARG Pro12Ala variant was conducted. The combined overall odds ratio, calculated by per-all...
Alendronate Induces Mineralization in Mouse Osteoblastic MC3T3-E1 Cells: Regulation of Mineralization-Related Genes
In conclusion, low-dose alendronate induced mineralization in mouse osteoblastic cells. The regulation of PC-1, osteocalcin and ALP by alendronate might play some role in these effects.[...]© J. A. Barth Verlag in Georg Thieme Verlag KG Stuttgart · New YorkGet connected:Table of contents  |  Abstract  |  Full text (Source: Experimental and Clinical Endocrinology and Diabetes)
Diabetes classification switch to force wave of patient reviews
GPs will have to re-assess around 40% of people with type-1 diabetes and 6% with type-2 diabetes, following the development of a new classification system. (Source: HealthcareRepublic Independent Nurse News)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Get the very latest Swine Flu news via the MedWorm <b><a href="http://www.medworm.com/rss/search.php?qu=%2Bswine+%2B%28influenza+flu%29&t=Swine+Flu&f=infectiousdiseases&r=Any&o=d" target ="_self">Swine Flu RSS news feed</a></b> - updated hourly from thousands of authoritative health and news sources.</p></div>
Diabetes, Insulin and Alzheimer's Disease
series:Research and Perspectives in Alzheimer's DiseaseNeurons share more similarities with insulin-producing pancreatic islet cells than with any other cell type. The root of this similarity may lie in the islet?s evolution from an ancestral insulin-producing neuron. The islet-neuron connection becomes less surprising as we learn more about insulin?s involvement in functions far from its traditional role in mediating glucose uptake in muscle. The ... (Source: Springer Biomedical Sciences titles)
Simple pharmacometric tools for oral anti-diabetic drug development: competitive landscape for oral non-insulin therapies in type 2 diabetes
In conclusion, the ability of system-specific parameters to predict HbA1c provides a tool to predict the expected efficacy profile from abbreviated dose-finding trials. To be commercially viable, new drugs should improve [Delta]HbA1c by about 0.8% or more and possess safety profiles similar to newer anti-diabetic agents. Thus, this study proposes a suite of simple yet powerful tools to guide type-2-diabetes drug development. Copyright © 2010 John Wiley & Sons, Ltd. (Source: Biopharmaceutics and Drug Disposition)
Another Advantage to Nursing the Baby
Newborn mice who receive their mother's milk experience a biological process that boosts their metabolism, possibly lowering the risk of obesity and diabetes in adulthood, according to a new study. Breast-feeding confers several protective benefits in... (Source: OrlandoSentinel: Medical Research)
Add diabetes to Ont. school policy: parents
Some Ontario families with school-aged children requiring medical attention for conditions such as Type 1 diabetes have major concerns about a health and education policy currently under review. (Source: CBC | Health)
Errors in Byline and Text in: Association Between Erythropoietin Gene Polymorphisms and Diabetic Retinopathy [Correction]
(Source: Archives of Opthalmology)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Get the very latest Swine Flu news via the MedWorm <b><a href="http://www.medworm.com/rss/search.php?qu=%2Bswine+%2B%28influenza+flu%29&t=Swine+Flu&f=infectiousdiseases&r=Any&o=d" target ="_self">Swine Flu RSS news feed</a></b> - updated hourly from thousands of authoritative health and news sources.</p></div>
Lack of Association Between Thiazolidinediones and Macular Edema in Type 2 Diabetes: The ACCORD Eye Substudy [Clinical Sciences]
Conclusions&nbsp; In a cross-sectional analysis of data from the largest study to date, no association was observed between thiazolidinedione exposure and DME in patients with type 2 diabetes; however, we cannot exclude a modest protective or harmful association. Trial Registration&nbsp; clinicaltrials.gov Identifier: NCT00542178 (Source: Archives of Opthalmology)
Food Surcharges and Subsidies: Putting Your Money Where Your Mouth Is [Editorial]
(Source: Archives of Internal Medicine)
Alcohol Consumption, Weight Gain, and Risk of Becoming Overweight in Middle-aged and Older Women [Original Investigation]
Conclusion&nbsp; Compared with nondrinkers, initially normal-weight women who consumed a light to moderate amount of alcohol gained less weight and had a lower risk of becoming overweight and/or obese during 12.9 years of follow-up. (Source: Archives of Internal Medicine)
Metrics for Evaluating the Utility of Patient-Centered Decision Tools [Editor's Correspondence]
(Source: Archives of Internal Medicine)
Metrics for Evaluating the Utility of Patient-Centered Decision Tools--Reply [Editor's Correspondence]
(Source: Archives of Internal Medicine)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Get the very latest Swine Flu news via the MedWorm <b><a href="http://www.medworm.com/rss/search.php?qu=%2Bswine+%2B%28influenza+flu%29&t=Swine+Flu&f=infectiousdiseases&r=Any&o=d" target ="_self">Swine Flu RSS news feed</a></b> - updated hourly from thousands of authoritative health and news sources.</p></div>
Amylin & Friends Brace for Diabetes Review (AMLN, LLY, ALKS)
Amylin Pharmaceuticals, Inc. (NASDAQ: AMLN) has a big event on deck this week.  This Friday, March 12, is its Prescription Drug User Fee Act (PDUFA) action date for an FDA panel to issue a recommendation on Byetta as the the first once a week treatment for Type II diabetes.  The date had been moved due to recent weather closures in February in and around Washington D.C. Analysts are mixed on the stock with BMO cutting its rating last week, but there were two positive calls from Credit Suisse and Jesup & Lamont. Options are elevated today, but not overly active.  The open interest of stock options is also large enough that the $20 synthetic options straddle would imply that shares have to rise above $24.70 or drop below $15.30 to be profitable. Byetta is already sold with Eli Lilly &...
Determinants of glycaemic control in type 2 diabetes African patients monitored by physicians from 1991 to 2004 in Cote d?Ivoire
Summary: The aim of this study was to propose determinants of glycaemic control which are useful to adequately manage the healthcare of type 2 diabetes patients attending an out-patient clinic. A retrospective, descriptive research design was implemented at the Centre AntiDiabétique d?Abidjan in 2399 African patients. Glycaemic control was calculated from the average of at least 12 fasting plasma glucose levels measured during at least three years. Logistic and multiple linear regressions were performed at the limit of the glycaemia average of 6.7mmol/l (120mg/dl). The determinants of poor glycaemic control were: long duration of monitoring (odds ratio (OR)=1.66, then 2.68), annual frequency of visits outside the 2?3 per year interval (OR=3.25) and insulin treatment (OR=4.66) in ?no...
US FDA Panel Sees Patient Errors With Insulin Pumps
Diabetics who wear insulin pumps appear more likely to experience problems from improper use than a device defect, members of a U.S. government advisory panel said on Friday. Reuters Health Information (Source: Medscape Medical News Headlines)
Wine and women's weight
Conclusion This large cohort study that followed middle-aged women for almost 13 years found that there was an association between greater alcohol consumption and slightly slower weight gain over this period. Despite the tone of press coverage, it should be remembered that this type of study can only show associations between factors, and cannot say how or whether alcohol directly causes the slower weight gain. There are also a number of limitations to this research, some of which the researchers have highlighted: The participants self-reported their weights and alcohol consumption, which may have resulted in a misclassification or underestimation of these values. The study used a single measurement of alcohol consumption taken at the start of the study. It is likely that the partici...
Company Profile: Tissue regeneration for diabetes and neurological diseases at Living Cell Technologies
Regenerative Medicine , March 2010, Vol. 5, No. 2, Pages 181-187. (Source: Future Medicine: Regenerative Medicine)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Get the very latest Swine Flu news via the MedWorm <b><a href="http://www.medworm.com/rss/search.php?qu=%2Bswine+%2B%28influenza+flu%29&t=Swine+Flu&f=infectiousdiseases&r=Any&o=d" target ="_self">Swine Flu RSS news feed</a></b> - updated hourly from thousands of authoritative health and news sources.</p></div>
Engaging patients is crucial to improving health outcomes
(Source: BMJ Online First)
Safflower and olive oil dietary treatments rescue aberrant embryonic arachidonic acid and nitric oxide metabolism and prevent diabetic embryopathy in rats
Aberrant arachidonic acid and nitric oxide (NO) metabolic pathways are involved in diabetic embryopathy. Previous works have found diminished concentrations of PGE2 and PGI2 in embryos from diabetic rats, and that PGI2 is capable of increasing embryonic PGE2 concentrations through the activation of the nuclear receptor PPAR. PPAR activators are lipid molecules such as oleic and linoleic acids, present in high concentrations in olive and safflower oils, respectively. The aim of this study was to analyze the capability of dietary supplementation with either 6% olive or 6% safflower oils to regulate PGE2, PGI2 and NO concentrations in embryos and deciduas from control and diabetic rats during early organogenesis. Diabetes was induced by a single injection of streptozotocin (55 mg/kg) 1 week b...
Continuous Subcutaneous Insulin Infusion Versus Multiple Daily Injections in Pregnant Women with Type 1 Diabetes
Diabetes Technology & Therapeutics Apr 2010, Vol. 12, No. 4: 263-269. (Source: Diabetes Technology)
STAR 3 Randomized Controlled Trial to Compare Sensor-Augmented Insulin Pump Therapy with Multiple Daily Injections in the Treatment of Type 1 Diabetes: Research Design, Methods, and Baseline Characteristics of Enrolled Subjects
Diabetes Technology & Therapeutics Apr 2010, Vol. 12, No. 4: 249-255. (Source: Diabetes Technology)
The Effects of Depression on Metabolic Control and Quality of Life in Indigent Patients with Type 2 Diabetes
Diabetes Technology & Therapeutics Apr 2010, Vol. 12, No. 4: 257-262. (Source: Diabetes Technology)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Get the very latest Swine Flu news via the MedWorm <b><a href="http://www.medworm.com/rss/search.php?qu=%2Bswine+%2B%28influenza+flu%29&t=Swine+Flu&f=infectiousdiseases&r=Any&o=d" target ="_self">Swine Flu RSS news feed</a></b> - updated hourly from thousands of authoritative health and news sources.</p></div>
Comparison of Various Maternal Anthropometric Indices of Obesity for Identifying Metabolic Syndrome in Offspring
Diabetes Technology & Therapeutics Apr 2010, Vol. 12, No. 4: 297-305. (Source: Diabetes Technology)
Insulin Requirement Profiles of Patients with Type 2 Diabetes After Achieving Stabilized Glycemic Control with Short-Term Continuous Subcutaneous Insulin Infusion
Diabetes Technology & Therapeutics Apr 2010, Vol. 12, No. 4: 271-281. (Source: Diabetes Technology)
Glucose Monitoring by Means of an Intravenous Microdialysis Catheter Technique
Diabetes Technology & Therapeutics Apr 2010, Vol. 12, No. 4: 291-295. (Source: Diabetes Technology)
Performance Evaluation of the GlucoDr Plus Glucometer
Diabetes Technology & Therapeutics Apr 2010, Vol. 12, No. 4: 307-312. (Source: Diabetes Technology)
Continuous Glucose Monitoring Reveals Associations of Glucose Levels with QT Interval Length
Diabetes Technology & Therapeutics Apr 2010, Vol. 12, No. 4: 283-286. (Source: Diabetes Technology)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Get the very latest Swine Flu news via the MedWorm <b><a href="http://www.medworm.com/rss/search.php?qu=%2Bswine+%2B%28influenza+flu%29&t=Swine+Flu&f=infectiousdiseases&r=Any&o=d" target ="_self">Swine Flu RSS news feed</a></b> - updated hourly from thousands of authoritative health and news sources.</p></div>
Effectiveness of Diabetes Educational Interventions in Iran: A Systematic Review
Diabetes Technology & Therapeutics Apr 2010, Vol. 12, No. 4: 317-331. (Source: Diabetes Technology)
Insulin Pump Therapy in Moslem Patients with Type 1 Diabetes During Ramadan Fasting: An Observational Report
Diabetes Technology & Therapeutics Apr 2010, Vol. 12, No. 4: 287-290. (Source: Diabetes Technology)
Dipeptidyl Peptidase-IV Inhibitors Are Efficient Adjunct Therapy in HNF1A Maturity-Onset Diabetes of the Young Patients?Report of Two Cases
Diabetes Technology & Therapeutics Apr 2010, Vol. 12, No. 4: 313-316. (Source: Diabetes Technology)
Extreme Sleep Duration Linked to Increased Abdominal Fat in Minority Young Adults
In a longitudinal study, extremes in sleep duration were related to increases in visceral and subcutaneous adipose tissue in minority young adults. Medscape Medical News (Source: Medscape FamilyMedicine Headlines)
Monitoring treatment response and outcomes using the World Health Organization's Wellbeing Index in psychiatric care
Conclusions: The current findings illustrate the potential of the WHO-5 as a quick, reliable and valid means for assessing patient outcome and monitoring patient response to treatment in psychiatric services. (Source: Journal of Affective Disorders)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Get the very latest Swine Flu news via the MedWorm <b><a href="http://www.medworm.com/rss/search.php?qu=%2Bswine+%2B%28influenza+flu%29&t=Swine+Flu&f=infectiousdiseases&r=Any&o=d" target ="_self">Swine Flu RSS news feed</a></b> - updated hourly from thousands of authoritative health and news sources.</p></div>
American Diabetes Association Applauds Senate's Efforts To Reauthorize Special Diabetes Programs
The American Diabetes Association applauds today's introduction of Special Diabetes Program legislation in the U.S. Senate. The bill (S. 3058) would reauthorize the Special Diabetes Type 1 Program and the Special Diabetes Program for Indians for 5 years. Each program would receive $200 million per year. Senator Byron L. Dorgan (D-ND), Chair of the Indian Affairs Committee, and Senator Susan M. Collins (R-ME), Co-Chair of the Diabetes Caucus, are the lead sponsors on the bill... (Source: Health News from Medical News Today)
What Will You Do To Stop DiabetesSM? Know Your Risk
What On the 22nd annual American Diabetes Association Alert Day, the American Diabetes Association will encourage people to join the Stop Diabetes movement by taking the Diabetes Risk Test to find out if they are at risk for developing type 2 diabetes and, if they are at high risk, to speak with their health care provider. Who The American Diabetes Association is leading the fight to stop diabetes and its deadly consequences and fighting for those affected by diabetes... (Source: Health News from Medical News Today)
American Diabetes Association Applauds Senate's Efforts To Reauthorize Special Diabetes Programs
The American Diabetes Association applauds today's introduction of Special Diabetes Program legislation in the U.S. Senate. The bill (S. 3058) would reauthorize the Special Diabetes Type 1 Program and the Special Diabetes Program for Indians for 5 years. Each program would receive $200 million per year. Senator Byron L... (Source: Diabetes News From Medical News Today)
What Will You Do To Stop DiabetesSM? Know Your Risk
What On the 22nd annual American Diabetes Association Alert Day, the American Diabetes Association will encourage people to join the Stop Diabetes movement by taking the Diabetes Risk Test to find out if they are at risk for developing type 2 diabetes and, if they are at high risk, to speak with their health care provider... (Source: Diabetes News From Medical News Today)
Max Planck Scientists Develop A Fingerprint For Genes: New Strategy To Play Major Role In Research On Human Diseases
Cells may not have a mouth, but they still need to ingest substances from the external environment. If this process - known as endocytosis - is affected, it can lead to infectious diseases or cardio-vascular diseases, cancer, Huntington's and diabetes... (Source: Infectious Diseases / Bacteria / Viruses News From Medical News Today)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Get the very latest Swine Flu news via the MedWorm <b><a href="http://www.medworm.com/rss/search.php?qu=%2Bswine+%2B%28influenza+flu%29&t=Swine+Flu&f=infectiousdiseases&r=Any&o=d" target ="_self">Swine Flu RSS news feed</a></b> - updated hourly from thousands of authoritative health and news sources.</p></div>
Max Planck Scientists Develop A Fingerprint For Genes: New Strategy To Play Major Role In Research On Human Diseases
Cells may not have a mouth, but they still need to ingest substances from the external environment. If this process - known as endocytosis - is affected, it can lead to infectious diseases or cardio-vascular diseases, cancer, Huntington's and diabetes. In cooperation with the Center for Information Services and High Performance Computing (ZIH) at the Dresden University of Technology, scientists from the Max Planck Institute of Molecular Cell Biology and Genetics therefore applied a new strategy to identify and characterize genes involved in endocytosis... (Source: Health News from Medical News Today)
Major Depression More Than Doubles Risk Of Dementia Among Adults With Diabetes
Adults who have both diabetes and major depression are more than twice as likely to develop dementia, compared to adults with diabetes only, according to a study published in the recent Journal of General Internal Medicine. Dementia is the progressive decline of thinking and reasoning abilities. These can include memory loss, difficulty with basic math, wandering, living in the past, personality changes, and not recognizing familiar people. "Diabetes alone has shown to be a risk factor for dementia, as has major depression by itself," noted the lead author of the study, Dr... (Source: Health News from Medical News Today)
Major Depression More Than Doubles Risk Of Dementia Among Adults With Diabetes
Adults who have both diabetes and major depression are more than twice as likely to develop dementia, compared to adults with diabetes only, according to a study published in the recent Journal of General Internal Medicine. Dementia is the progressive decline of thinking and reasoning abilities... (Source: Diabetes News From Medical News Today)
Intestinal bacteria drive obesity and metabolic disease in immune-altered mice
Mice lacking a gene called TLR5 have an altered ability to recognize and control bacteria in their intestines, leading them to develop obesity and insulin resistance, which is often referred to as "pre-diabetes." The bacteria appear to influence appetite and metabolism rather than how well calories are absorbed. Obesity and insulin resistance can be transferred from TLR5-deficient mice via intestinal bacteria. (Source: ScienceDaily Headlines)
Major depression more than doubles risk of dementia among adults with diabetes
Adults with both depression and diabetes are more than twice as likely to develop dementia compared to those with diabetes alone. Earlier studies have shown that depression alone is a risk factor for dementia, and that diabetes itself is a dementia risk factor. Researchers found even greater risk of dementia in people with both conditions. The mechanisms behind this increased risk are not yet clear. The researchers suggest that physicians screen and treat their diabetes patients for depression, which is common in people with diabetes. (Source: ScienceDaily Headlines)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Get the very latest Swine Flu news via the MedWorm <b><a href="http://www.medworm.com/rss/search.php?qu=%2Bswine+%2B%28influenza+flu%29&t=Swine+Flu&f=infectiousdiseases&r=Any&o=d" target ="_self">Swine Flu RSS news feed</a></b> - updated hourly from thousands of authoritative health and news sources.</p></div>
Drinking Sugar-Sweetened Beverages Daily Linked To Diabetes, Cardiovascular Disease, Increased Healthcare Costs
More Americans now drink sugar-sweetened sodas, sport drinks and fruit drinks daily, and this increase in consumption has led to more diabetes and heart disease over the past decade, researchers reported at the American Heart Association's 50th Annual Conference on Cardiovascular Disease Epidemiology and Prevention... (Source: Health News from Medical News Today)
Drinking Sugar-Sweetened Beverages Daily Linked To Diabetes, Cardiovascular Disease, Increased Healthcare Costs
More Americans now drink sugar-sweetened sodas, sport drinks and fruit drinks daily, and this increase in consumption has led to more diabetes and heart disease over the past decade, researchers reported at the American Heart Association's 50th Annual Conference on Cardiovascular Disease Epidemiology and Prevention... (Source: Diabetes News From Medical News Today)
More Info Needed on Problems With Insulin Pumps
Title: More Info Needed on Problems With Insulin PumpsCategory: Health NewsCreated: 3/5/2010 6:10:00 PMLast Editorial Review: 3/8/2010 (Source: MedicineNet Diabetes General)
Increasing Soda Consumption Fuels Rise in Diabetes, Heart Disease
Title: Increasing Soda Consumption Fuels Rise in Diabetes, Heart DiseaseCategory: Health NewsCreated: 3/5/2010 8:10:00 PMLast Editorial Review: 3/8/2010 (Source: MedicineNet Diabetes General)
Processed Meat May Harm the Heart
Title: Processed Meat May Harm the HeartCategory: Health NewsCreated: 3/5/2010 8:10:00 PMLast Editorial Review: 3/8/2010 (Source: MedicineNet Diabetes General)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Get the very latest Swine Flu news via the MedWorm <b><a href="http://www.medworm.com/rss/search.php?qu=%2Bswine+%2B%28influenza+flu%29&t=Swine+Flu&f=infectiousdiseases&r=Any&o=d" target ="_self">Swine Flu RSS news feed</a></b> - updated hourly from thousands of authoritative health and news sources.</p></div>
Increasing Soda Consumption Fuels Rise in Diabetes, Heart Disease
Title: Increasing Soda Consumption Fuels Rise in Diabetes, Heart DiseaseCategory: Health NewsCreated: 3/5/2010 8:10:00 PMLast Editorial Review: 3/8/2010 (Source: MedicineNet Senior Health General)
Obesity as protection against metabolic syndrome, not its cause
(Cell Press) The collection of symptoms that is the metabolic syndrome -- insulin resistance, high cholesterol, fatty liver, and a greater risk for diabetes, heart disease, and stroke -- are all related to obesity, but, according to a review in the March 9 issue of the Cell Press publication Trends in Endocrinology and Metabolism, not in the way you probably think they are. (Source: EurekAlert! - Biology)
Diabetes influences life-changing decisions
Diabetes influences decisions about life-changing events for three quarters of people who have the condition, a UK study has shown. (Source: HealthcareRepublic Independent Nurse News)
Diabetics are offered £250 course to help them manage disease
PATIENTS with diabetes are being offered a qualification to help them manage their condition, reducing the risk of complications. (Source: Scotsman.com News - Health)
Trends of hospitalizations, fatality rate and costs for acute myocardial infarction among Spanish diabetic adults, 2001-2006.
Conclusions: Diabetic patients have higher rates of hospital admission and fatality rates during the hospitalization after an AMI than nondiabetic patients. Diabetic adults who have suffered an AMI have a greater than expected increase in direct hospital costs over the period 2001-2006. (Source: BMC Health Services Research)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Get the very latest Swine Flu news via the MedWorm <b><a href="http://www.medworm.com/rss/search.php?qu=%2Bswine+%2B%28influenza+flu%29&t=Swine+Flu&f=infectiousdiseases&r=Any&o=d" target ="_self">Swine Flu RSS news feed</a></b> - updated hourly from thousands of authoritative health and news sources.</p></div>
Standardized protocol for a depletion of intramyocellular lipids (IMCL)
Intramyocellular lipids (IMCL) are flexible fuel stores that are depleted by physical exercise and replenished by fat intake. IMCL or their degradation products are thought to interfere with insulin signaling thereby contributing to insulin resistance. From a practical point of view it is desirable to deplete IMCL prior to replenishing them. So far, it is not clear for how long and at which intensity subjects have to exercise in order to deplete IMCL. We therefore aimed at developing a standardized exercise protocol that is applicable to subjects over a broad range of exercise capacity and insulin sensitivity and allows measuring reliably reduced IMCL levels.Twelve male subjects, including four diabetes type 2 patients, with wide ranges of exercise capacity (VO2peak per total body weight 2...
Immunological detection of fructose-derived advanced glycation end-products
Authors: Masayoshi Takeuchi, Mina Iwaki, Jun-ichi Takino, Hikari Shirai, Mihoko Kawakami, Richard Bucala & Sho-ichi Yamagishi (Source: Laboratory Investigation AOP)
Thoracoabdominal calcifications predict CVD and total mortality
Thoracoabdominal calcification predicts cardiovascular disease and total mortality in Type 2 diabetics and nondiabetics, say investigators. (Source: MedWire News - Diabetes)
Association of the C677T polymorphism in the methylenetetrahydrofolate reductase gene with sudden sensorineural hearing loss
To investigate the recently reported association of the C677T polymorphism in the methylenetetrahydrofolate reductase (MTHFR) gene with sudden sensorineural hearing loss (SSNHL), we analyzed data from a community-based Japanese population.Nested case-control study.Among 2,174 adults (1,096 males and 1,078 females) aged 40 to 79 years old who participated in the National Institute for Longevity Sciences-Longitudinal Study of Aging, we compared 33 cases of prevalent SSNHL, defined as a self-reported otolaryngologist diagnosis, with the other cases. Multiple logistic regression was used to obtain odds ratios (ORs) for SSNHL in subjects with the MTHFR C677T polymorphism, with adjustment for other possibly influential factors under additive, dominant, and recessive genetic models.The per-allele...
AHA: Sugary Beverages Linked to Heart Disease Burden
In individuals 35 years of age or older, the increased consumption of sugar-sweetened beverages between 1990 and 2000 may have contributed to new cases of diabetes, coronary heart disease, and additional life-years burdened by coronary heart disease from 2000 to 2010, contributing to significant cardiovascular burden over time, according to research presented at the American Heart Association's joint conference of the Council on Epidemiology and Prevention and the Council on Nutrition, Physical Activity and Metabolism, held from March 2 to 5 in San Francisco. (Source: Modern Medicine)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Get the very latest Swine Flu news via the MedWorm <b><a href="http://www.medworm.com/rss/search.php?qu=%2Bswine+%2B%28influenza+flu%29&t=Swine+Flu&f=infectiousdiseases&r=Any&o=d" target ="_self">Swine Flu RSS news feed</a></b> - updated hourly from thousands of authoritative health and news sources.</p></div>
Increasing Soda Consumption Fuels Rise in Diabetes, Heart Disease
Finding suggests new health policies could make a dent in the problem, researcher says Source: HealthDay Related MedlinePlus Pages: Carbohydrates, Diabetes, Heart Diseases (Source: MedlinePlus Health News)
Processed Meat May Harm the Heart
Salt and preservatives may be the culprits, researchers suggest Source: HealthDay Related MedlinePlus Pages: Diabetes, Heart Diseases, Nutrition (Source: MedlinePlus Health News)
Summaries of Nursing Care-Related Systematic Reviews from the Cochrane Library: Individual patient education for people with type 2 diabetes mellitus
(Source: International Journal of Evidence-Based Healthcare)
Study on the Postprandial Blood Glucose Suppression Effect of D-Psicose in Borderline Diabetes and the Safety of Long-Term Ingestion by Normal Human Subjects.
Authors: Hayashi N, Iida T, Yamada T, Okuma K, Takehara I, Yamamoto T, Yamada K, Tokuda M This clinical study was conducted to investigate the safety and effect of D-psicose on postprandial blood glucose levels in adult men and women, including borderline diabetes patients. A randomized double-blind placebo-controlled crossover experiment of single ingestion was conducted on 26 subjects who consumed zero or 5 g of D-psicose in tea with a standard meal. The blood glucose levels at fasting and 30, 60, 90, and 120 min after the meal were compared. The blood glucose level was significantly lower 30 and 60 min after the meal with D-psicose (p&lt;0.01, p&lt;0.05), and a significant decrease was also shown in the area under the curve (p&lt;0.01). The results suggest that D-psicose had an effe...
The Changing Landscape of Biotech Valuations (ACOR, CBST, MNKD, INCY, SGEN, ITMN, IPXL, MRX, SVNT, VPHM)
The biotech and biohealth universe is changing in size.  In 2008 and 2009, partly due to mergers and partly due to market valuations, there had become a surprisingly small number of biotech stocks which had market capitalization rates of more than $1 billion.  At one point there were only about 10 or 11 in our universe of biotech stocks that actually had market caps which were very far north of $1 billion, or at least out of the biotech stocks which followed at BioHealth Investor. We have recently seen Acorda Therapeutics, Inc. (NASDAQ: ACOR), Cubist Pharmaceuticals Inc. (NASDAQ: CBST), MannKind Corporation (NASDAQ: MNKD), Incyte Corporation (NASDAQ: INCY), Seattle Genetics, Inc. (NASDAQ: SGEN), InterMune, Inc. (NASDAQ: ITMN), Impax Laboratories Inc. (NASDAQ: IPXL), and Medicis Pharmaceu...<div id="medworm"><p><b><i>MedWorm Message:</i></b> Get the very latest Swine Flu news via the MedWorm <b><a href="http://www.medworm.com/rss/search.php?qu=%2Bswine+%2B%28influenza+flu%29&t=Swine+Flu&f=infectiousdiseases&r=Any&o=d" target ="_self">Swine Flu RSS news feed</a></b> - updated hourly from thousands of authoritative health and news sources.</p></div>
Drinking sugar-sweetened beverages daily linked to diabetes
More Americans now drink sugar-sweetened sodas, sport drinks and fruit drinks daily, and this increase in consumption has led to more diabetes and heart disease over the past decade, researchers report. (Source: ScienceDaily Headlines)
No evidence for adverse effects of vildagliptin
Results from two meta-analyses investigating the safety profile of the dipeptidyl peptidase-4 inhibitor vildagliptin found no evidence for increased cardiovascular, cerebrovascular, or liver-related adverse effects associated with the drug versus all comparators. (Source: MedWire News - Diabetes)
Study Examines Perceived Barriers To Care For At-Risk Patients With Diabetes
Diabetes affects approximately 8 percent of the people in the United States and adults with diabetes have heart disease death rates two to four times higher than adults without diabetes, according to the American Diabetes Association. A new study shows that primary care physicians believe the barriers that put patients with uncontrolled diabetes at risk for cardiovascular disease as being patient-related or system-related... (Source: Health News from Medical News Today)
Study Examines Perceived Barriers To Care For At-Risk Patients With Diabetes
Diabetes affects approximately 8 percent of the people in the United States and adults with diabetes have heart disease death rates two to four times higher than adults without diabetes, according to the American Diabetes Association... (Source: Cardiovascular / Cardiology News From Medical News Today)
The Therapeutic Effect Of Worm-Derived Proteins On Experimental Colitis
Patients with inflammatory bowel disease (IBD) suffer from chronic inflammation of the gut leading to gastrointestinal motility alterations with symptoms such as abdominal pain, cramps and diarrhea that profoundly affect their quality of life... (Source: Diabetes News From Medical News Today)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Get the very latest Swine Flu news via the MedWorm <b><a href="http://www.medworm.com/rss/search.php?qu=%2Bswine+%2B%28influenza+flu%29&t=Swine+Flu&f=infectiousdiseases&r=Any&o=d" target ="_self">Swine Flu RSS news feed</a></b> - updated hourly from thousands of authoritative health and news sources.</p></div>
Use blood glucose numbers to better manage diabetes
Use these tips to get more out of your blood glucose monitoring. (Source: MayoClinic.com Full Feed)
Antioxidant and antiglycation properties of triterpenoid saponins from Aralia taibaiensis traditionally used for treating diabetes mellitus.
Authors: Xi M, Hai C, Tang H, Wen A, Chen H, Liu R, Liang X, Chen M Our previous study has demonstrated that the antidiabetic activity of the extract of root bark of Aralia taibaiensis (EAT) was correlated with its combined antioxidant and antiglycation properties. To confirm further the constituents responsible, 12 triterpenoid saponins were isolated from EAT and examined for their antioxidant and antiglycation activities. The antioxidant activities of the pure compounds and EAT were evaluated by studying the inhibition of lipid peroxidation in rat liver microsomes induced by ascorbate/Fe(2+), cumine hydroperoxide (CHP) or CCl(4)/reduced form of nicotinamide-adenine dinucleotide phosphate (NADPH). The antioxidant capacities were also evaluated by studying the scavenging of 2,2-dipheny...
Key considerations around the risks and consequences of hypoglycaemia in people with type 2 diabetes
Hypoglycaemia and its consequences represent a significant risk for many people who have type 2 diabetes, and hypoglycaemia is currently under-recognised and commonly avoidable. Current clinical guidelines recommend the targeting of tight glycaemic control and this strategy may also be associated with an increased risk of hypoglycaemia. Hypoglycaemia impacts on morbidity, mortality and quality of life of people with type 2 diabetes, and improved recognition of the symptoms of hypoglycaemia will allow effective treatment and reduce the risk of progression to more severe episodes. A common cause of hypoglycaemia in people with type 2 diabetes is glucose-lowering medication, in particular, those which raise insulin independently of ambient glucose concentration such as sulphonylureas and exog...
FDA Approves New Somatropin Injection Pen for Growth Hormone Disorders
The FDA has approved a prefilled somatropin injection pen for the treatment of growth hormone disorders in adult and pediatric patients. It is expected to be available in the second quarter of 2010. Medscape Medical News (Source: Medscape Today Headlines)
More Info Needed on Problems with Insulin Pumps
Not clear if troubles stem from the devices or patient error, FDA panel says Source: HealthDay Related MedlinePlus Pages: Diabetes Type 1, Medical Device Safety (Source: MedlinePlus Health News)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Get the very latest Swine Flu news via the MedWorm <b><a href="http://www.medworm.com/rss/search.php?qu=%2Bswine+%2B%28influenza+flu%29&t=Swine+Flu&f=infectiousdiseases&r=Any&o=d" target ="_self">Swine Flu RSS news feed</a></b> - updated hourly from thousands of authoritative health and news sources.</p></div>
Major depression more than doubles risk of dementia among adults with diabetes
Adults who have both diabetes and depression are more than twice as likely to develop dementia -- a progressive decline of memory, reasoning, and other thinking skills -- than are people with diabetes alone. (Source: uwnews.org | Health and Medicine)
Differential Effects of Various Typical and Atypical Antipsychotics on Plasma Glucose and Insulin Levels in the Mouse: Evidence for the Involvement of Sympathetic Regulation
Atypical antipsychotic treatment has been associated with serious metabolic adverse events, such as glucose dysregulation and development of type 2 diabetes. As part of our studies on possible underlying mechanisms, we investigated the acute effects of various typical and atypical antipsychotics on plasma glucose and insulin in FVB/N mice, a strain that showed a more pronounced hyperglycemic response to clozapine than C57BL/6 and CD-1 mice. Acute administration of high doses of clozapine, olanzapine, quetiapine, perphenazine, or chlorpromazine significantly increased plasma glucose by 100%&ndash;140% above basal levels without significant effects on insulin levels. In contrast, risperidone reduced plasma glucose (&ndash;30%) and markedly enhanced plasma insulin levels. Doses of ziprasidone...
Does Adherence to Medications for Type 2 Diabetes Differ Between Individuals With Vs Without Schizophrenia?
Individuals with schizophrenia are at increased risk for poor health outcomes and mortality. This may be due to inadequate self-management of co-occurring conditions, such as type 2 diabetes. We compared adherence to oral hypoglycemic medications for diabetes patients with vs without comorbid schizophrenia. Using Veterans Affairs (VA) health system administrative data, we identified all patients with both schizophrenia and type 2 diabetes and with at least one oral hypoglycemic prescription fill in fiscal year 2002 (N = 11 454) and a comparison group of patients with diabetes who were not diagnosed with schizophrenia (N = 10 560). Nonadherence was operationalized as having a medication possession ratio indicating receipt of less than 80% of needed hypoglycemic medications. Poor adherence w...
Lunchtime coffee break best for fighting diabetes
NEW YORK (Reuters Health) - Drinking coffee cuts diabetes risk, new research confirms, but you may need to enjoy your java with lunch if you want to get any benefit. (Source: Reuters: Health)
Lunchtime Coffee Break Best for Fighting Diabetes
Drinking coffee cuts diabetes risk, new research confirms, but you may need to enjoy your java with lunch if you want to get any benefit.Source: Reuters Health Related MedlinePlus Pages: Diabetes, Nutrition (Source: MedlinePlus Health News)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Get the very latest Swine Flu news via the MedWorm <b><a href="http://www.medworm.com/rss/search.php?qu=%2Bswine+%2B%28influenza+flu%29&t=Swine+Flu&f=infectiousdiseases&r=Any&o=d" target ="_self">Swine Flu RSS news feed</a></b> - updated hourly from thousands of authoritative health and news sources.</p></div>
Eye Condition Linked To Weakened Brain Power In People With Diabetes, Says New Research
Diabetic retinopathy could be associated with poorer memory and diminished brain power in people with Type 2 diabetes, according to new research announced this week at Diabetes UK's Annual Professional Conference. The study looked at 1,066 people with Type 2 diabetes aged between 60 and 75 years. Participants completed seven tests looking at memory, logic and concentration to establish their level of brain function. Those with retinopathy had worse average scores on most of the individual tests as well as on general cognitive ability compared to those without the condition... (Source: Health News from Medical News Today)
Eye Condition Linked To Weakened Brain Power In People With Diabetes, Says New Research
Diabetic retinopathy could be associated with poorer memory and diminished brain power in people with Type 2 diabetes, according to new research announced this week at Diabetes UK's Annual Professional Conference. The study looked at 1,066 people with Type 2 diabetes aged between 60 and 75 years... (Source: Diabetes News From Medical News Today)
Continuous Intraperitoneal Insulin Linked With Better Quality of Life
Patients report higher quality of life with continuous intraperitoneal versus subcutaneous insulin, Dutch investigators have found. Reuters Health Information (Source: Medscape Diabetes Headlines)
Could Germs Be Making People Fat?
Germs that make their home in the gut may help cause obesity and a range of health-threatening symptoms that go along with it, researchers reported on Thursday. Reuters Health Information (Source: Medscape Medical News Headlines)
[News of the Week] ScienceNOW.org: From Science's Online Daily News Site
ScienceNOW reported this week that an early polar bear has been discovered in Arctic tundra, an appetite-suppressing hormone called leptin is just as effective as insulin at controlling diabetes in mice, engraved eggs suggest early symbolism, and global warming didn't kill the golden toad, among other stories. (Source: Science: Current Issue)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Get the very latest Swine Flu news via the MedWorm <b><a href="http://www.medworm.com/rss/search.php?qu=%2Bswine+%2B%28influenza+flu%29&t=Swine+Flu&f=infectiousdiseases&r=Any&o=d" target ="_self">Swine Flu RSS news feed</a></b> - updated hourly from thousands of authoritative health and news sources.</p></div>
SRT1720, SRT2183, SRT1460, and Resveratrol Are Not Direct Activators of SIRT1 [Enzymology]
Sirtuins catalyze NAD+-dependent protein deacetylation and are critical regulators of transcription, apoptosis, metabolism, and aging. There are seven human sirtuins (SIRT1&ndash;7), and SIRT1 has been implicated as a key mediator of the pathways downstream of calorie restriction that have been shown to delay the onset and reduce the incidence of age-related diseases such as type 2 diabetes. Increasing SIRT1 activity, either by transgenic overexpression of the Sirt1 gene in mice or by pharmacological activation by small molecule activators resveratrol and SRT1720, has shown beneficial effects in rodent models of type 2 diabetes, indicating that SIRT1 may represent an attractive therapeutic target. Herein, we have assessed purported SIRT1 activators by employing biochemical assays utilizing...
A Noncatalytic Domain of Glycogen Synthase Kinase-3 (GSK-3) Is Essential for Activity [Protein Structure and Folding]
We examined the effect of these mutations on GSK-3 activity toward Tau, activity in Wnt signaling, interaction with Axin, and GSK-3/&beta; Tyr279/216 phosphorylation. We found that the N termini of both GSK-3 isoforms were dispensable, whereas progressive C-terminal deletions resulted in protein misfolding exhibited by deficient activity, impaired ability to interact with Axin, and a loss of Tyr279/216 phosphorylation. Our data predict that small molecules targeting the divergent C terminus may lead to isoform-specific GSK-3 inhibition through destabilization of the GSK-3 structure. (Source: Journal of Biological Chemistry)
Solution Structure of Proinsulin: CONNECTING DOMAIN FLEXIBILITY AND PROHORMONE PROCESSING [Protein Structure and Folding]
The folding of proinsulin, the single-chain precursor of insulin, ensures native disulfide pairing in pancreatic &beta;-cells. Mutations that impair folding cause neonatal diabetes mellitus. Although the classical structure of insulin is well established, proinsulin is refractory to crystallization. Here, we employ heteronuclear NMR spectroscopy to characterize a monomeric analogue. Proinsulin contains a native-like insulin moiety (A- and B-domains); the tethered connecting (C) domain (as probed by {1H}-15N nuclear Overhauser enhancements) is progressively less ordered. Although the BC junction is flexible, residues near the CA junction exhibit -helical-like features. Relative to canonical -helices, however, segmental 13C/&beta; chemical shifts are attenuated, suggesting that this junction...
Diabetic women have high HbA1c in late pregnancy due to iron deficiency
Results show that diabetic women in late pregnancy have elevated glycated hemoglobin, but not serum glycated albumin levels, and this is likely due to iron deficiency. (Source: MedWire News - Diabetes)
Pattern of cutaneous manifestations in diabetes mellitus
Conclusion:&#x0026;lt;/b&#x0026;gt; Skin is involved in diabetes quite often and the manifestations are numerous. High prevalence of xerosis in our diabetic population is perhaps due to cold and dry climatic conditions in the region for most of the time in the year. (Source: Indian Journal of Dermatology)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Get the very latest Swine Flu news via the MedWorm <b><a href="http://www.medworm.com/rss/search.php?qu=%2Bswine+%2B%28influenza+flu%29&t=Swine+Flu&f=infectiousdiseases&r=Any&o=d" target ="_self">Swine Flu RSS news feed</a></b> - updated hourly from thousands of authoritative health and news sources.</p></div>
Sugary soft drinks lead to diabetes, research finds
Drinking sugar-sweetened soft drinks has been linked to an increase in new cases of diabetes and heart disease. (Source: Telegraph Health)
HbA1c More Predictive than Glucose (CME/CE)
Glycated hemoglobin (HbA1c) outperformed blood glucose as a predictor of cardiovascular disease and all-cause mortality and had similar predictive accuracy for diabetes, data from a large cohort study showed. (Source: MedPage Today Cardiovascular)
Unusual Mid-shaft Fractures During Long-term Bisphosphonate Therapy
Although existing evidence supports a good safety profile, there is concern that these agents could result in severe suppression of bone turnover with increased risk of nonvertebral fractures. Clinical Endocrinology (Source: Medscape Today Headlines)
A Randomized Evaluation of Loss and Gain Frames in an Invitation to Screening for Type 2 Diabetes: Effects on Attendance, Anxiety and Self-rated Health
A randomized controlled trial in two general practices in Cambridgeshire compared the effect of loss and gain framed messages in an invitation to screening for type 2 diabetes on uptake and subsequent anxiety and self-rated health. High risk individuals aged 40&mdash;69 years were randomized to receive loss (n = 57) or gain (n = 59) framed screening invitations. A postal questionnaire was sent to all participants, including non-attenders, after six weeks. There were no significant differences in attendance, mean state anxiety, self-rated health or illness representation between the loss and gain frame arms. Framing of information in diabetes screening invitations does not influence uptake. (Source: Journal of Health Psychology)
The variable phenotype of the p.A16V mutation of cationic trypsinogen (PRSS1) in pancreatitis families
Conclusions Penetrance of p.A16V is highly variable and family dependent, suggesting it contributes to multigenic inheritance of a predisposition to pancreatitis. (Source: Gut)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Get the very latest Swine Flu news via the MedWorm <b><a href="http://www.medworm.com/rss/search.php?qu=%2Bswine+%2B%28influenza+flu%29&t=Swine+Flu&f=infectiousdiseases&r=Any&o=d" target ="_self">Swine Flu RSS news feed</a></b> - updated hourly from thousands of authoritative health and news sources.</p></div>
Health benefits of nuts in prevention and management of diabetes.
Authors: Kendall CW, Esfahani A, Truan J, Srichaikul K, Jenkins DJ The effects of tree nuts on risk factors for coronary heart disease (CHD), in particular blood lipids, have been investigated in a number of studies and the beneficial effects are now recognized. The beneficial effects of nuts on CHD in cohort studies have also been clearly demonstrated. However, while there is also reason to believe the unique micro- and macronutrient profiles of nuts may help to control blood glucose levels, relatively few studies have investigated their role in diabetes control and prevention. Nuts are low in available carbohydrate, have a healthy fatty acid profile, and are high in vegetable protein, fiber and magnesium. Acute feeding studies indicate that when eaten alone nuts have minimal effects ...
Prevalence and characteristics of the metabolic syndrome among adults in Beijing, China.
This study was performed to investigate the prevalence of the metabolic syndrome using a large representative sample in Beijing. Data from a total of 16442 adults (6489 men and 9953 women) aged ?18 years from a survey of behavioral risk factors for chronic diseases in Beijing, in 2005, was analyzed. The prevalence of the metabolic syndrome increased with age and the age-standardized prevalence of the metabolic syndrome defined by International Diabetes Federation IDF and National Cholesterol Education Program Adult Treatment Panel III ATPIII criteria were 23.2% (24.5% in men and 22.7% in women) and 16.2% (16.1% in men and 16.6% in women), respectively. The metabolic syndrome was higher in semi-urban areas and associated with higher rates of hypertension, central obesity, salt intake and sm...
Economic analysis of a diabetes-specific nutritional meal replacement for patients with type 2 diabetes.
This study extends nutritional intervention results reported by short-term clinical trials of a diabetes-specific nutritional meal replacement by assessing the ten-year impact of the interventions on patient outcomes and costs compared to usual care. We developed and validated a computer simulation of type 2 diabetes based on published data from major clinical trials. The model tracks patients through microvascular and macrovascular health states and reports cumulative costs and quality adjusted life years. We modeled different scenarios that include a diabetes-specific nutritional meal replacement as part of a structured lifestyle intervention, and also as the only difference between the intervention and usual care treatment groups, and compared them to usual care with diet and physical a...
Regular painkillers and hearing loss
Conclusion This study found an association between regular use of three types of painkiller and a small increased risk in hearing loss. This type of study can only find associations, it cannot demonstrate that these painkillers caused the hearing loss. The researchers highlight some limitations of their study: Men were categorised as having hearing loss based on their own admission in the questionnaire on whether it had been diagnosed by a professional. Participants who did not report hearing loss were considered to not be impaired. The best way to assess hearing would have been through standard pure-tone audiometry, but this could not be performed due to cost and logistics reasons. The researchers did not have information on the participants? lifetime noise exposure or the reasons...
New Technique Will Probe Hidden Dynamics Of Molecular Biology
Funded by a $1 million grant from the W.M. Keck Foundation, University of Chicago scientists are aiming to develop a systematic method for determining how biological processes emerge from molecular interactions. The method may permit them to "rewire" the regulatory circuitry of insulin-secreting pancreatic beta cells, which play a major role in type-2 diabetes... (Source: Health News from Medical News Today)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Get the very latest Swine Flu news via the MedWorm <b><a href="http://www.medworm.com/rss/search.php?qu=%2Bswine+%2B%28influenza+flu%29&t=Swine+Flu&f=infectiousdiseases&r=Any&o=d" target ="_self">Swine Flu RSS news feed</a></b> - updated hourly from thousands of authoritative health and news sources.</p></div>
People With Prediabetes Not Taking Adequate Precautions To Avoid Diabetes - New Study Published In The American Journal Of Preventive Medicine
In 2005-2006, almost 30% of the U.S. adult population had prediabetes, but over 90% were unaware of their prediabetes status. Although it is known that diabetes can be prevented or delayed among adults at high risk through modest weight loss and increased physical activity, a study published in the April 2010 issue of the American Journal of Preventive Medicine revealed that only about half of U.S. adults with prediabetes reported that in the past year they tried to lose weight or exercise more... (Source: Health News from Medical News Today)
New Technique Will Probe Hidden Dynamics Of Molecular Biology
Funded by a $1 million grant from the W.M. Keck Foundation, University of Chicago scientists are aiming to develop a systematic method for determining how biological processes emerge from molecular interactions. The method may permit them to "rewire" the regulatory circuitry of insulin-secreting pancreatic beta cells, which play a major role in type-2 diabetes... (Source: Diabetes News From Medical News Today)
People With Prediabetes Not Taking Adequate Precautions To Avoid Diabetes - New Study Published In The American Journal Of Preventive Medicine
In 2005-2006, almost 30% of the U.S. adult population had prediabetes, but over 90% were unaware of their prediabetes status. Although it is known that diabetes can be prevented or delayed among adults at high risk through modest weight loss and increased physical activity, a study published in the April 2010 issue of the American Journal of Preventive Medicine revealed that only about half of U... (Source: Diabetes News From Medical News Today)
Pycnogenol Lowers Elevated Urinary Protein Levels And Improves Blood Flow To The Kidneys
An estimated one in ten adults suffers from kidney disease, according to the National Institute of Diabetes and Digestive and Kidney Diseases. A leading cause of kidney disease is hypertension, which effects one out of every four U.S. adults. Chronically high blood pressure damages capillaries of the kidneys which in turn affects the organ's ability to filter waste and remove excess fluids from the body... (Source: Health News from Medical News Today)
Pycnogenol Lowers Elevated Urinary Protein Levels And Improves Blood Flow To The Kidneys
An estimated one in ten adults suffers from kidney disease, according to the National Institute of Diabetes and Digestive and Kidney Diseases. A leading cause of kidney disease is hypertension, which effects one out of every four U.S. adults... (Source: Hypertension News From Medical News Today)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Get the very latest Swine Flu news via the MedWorm <b><a href="http://www.medworm.com/rss/search.php?qu=%2Bswine+%2B%28influenza+flu%29&t=Swine+Flu&f=infectiousdiseases&r=Any&o=d" target ="_self">Swine Flu RSS news feed</a></b> - updated hourly from thousands of authoritative health and news sources.</p></div>
St. Jude Medical Announces Publication Of Feasibility Results For Trial Of Novel Heart Failure Management System
St. Jude Medical, Inc. (NYSE:STJ) announced publication of clinical results in the Hemodynamically Guided Home Self-Therapy in Severe Heart Failure Patients (HOMEOSTASIS) trial. The left atrial pressure (LAP) management system featured in this study allows patients to adjust their heart failure (HF) medications daily, based on a physician-directed prescription plan and their current HF status, similar to the manner in which diabetes patients manage their insulin therapy. Results of the HOMEOSTASIS study were published in the March 2010 issue of Circulation... (Source: Health News from Medical News Today)
Weight-Loss Surgery Can Lead To Psychological Distress
People who have gastric band surgery to lose weight are at risk of low self-esteem, relationship problems and being dissatisfied with their body image, according to new research being presented at the Diabetes UK Annual Professional Conference (APC). Researchers from the University of the West of England and Southmead Hospital, Bristol, followed 25 patients aged from 30 to 58 years and recorded their experience 12 months after receiving a post-laparoscopic gastric banding operation. 64 per cent of the participants had Type 2 diabetes... (Source: Health News from Medical News Today)
Weight-Loss Surgery Can Lead To Psychological Distress
People who have gastric band surgery to lose weight are at risk of low self-esteem, relationship problems and being dissatisfied with their body image, according to new research being presented at the Diabetes UK Annual Professional Conference (APC)... (Source: Obesity / Weight Loss / Fitness News From Medical News Today)
In-Hospital Complications and Mortality Following Major Lower Extremity Amputations in a Series of Predominantly Diabetic Patients
The purpose of this study was to analyze the outcomes of major lower extremity amputations (MLEAs) in a series, including diabetic patients, with the aim to study whether diabetes mellitus is a risk factor of in-hospital mortality and perioperative complications. A retrospective analysis of 283 MLEAs (221 of these patients were diabetic and 62 were nondiabetic) performed between January 1, 1998, and December 31, 2008, at the General Surgery Department and Diabetic Foot Unit of La Paloma Hospital in Las Palmas de Gran Canaria (Canary Islands) was done. The significant risk factors of mortality were &gt;" xbd="324" xhg="301" ybd="1481" yhg="1446"/&gt;75 years of age (odds ratio [OR] = 4.1, 95% confidence interval [CI] = 1.4-11.7), postoperative cardiac complications (OR = 12.3, 95% CI = 3.7-...
Diabetic Foot Infections: A Need for Innovative Assessments
Foot wounds are the most common diabetes-related cause of hospitalization and frequently result in amputation. Although generally diagnosed clinically based on signs and symptoms of inflammation, empirical antibiotic treatment should be based on tissue cultures until resolution of infection. Advances in molecular detection over the past decade, including rapid chromogenic agar and real-time polymerase chain reaction, have improved diagnostic capabilities. However, chronic wounds may host biofilm bacteria not adequately detected by current microbiological testing. Enhanced DNA testing is required to identify these pathogens as well as evolving and previously underdiagnosed bacteria. Two options, nucleic acid fluorescent in situ hybridization and rDNA sequencing, are on the horizon for clini...<div id="medworm"><p><b><i>MedWorm Message:</i></b> Get the very latest Swine Flu news via the MedWorm <b><a href="http://www.medworm.com/rss/search.php?qu=%2Bswine+%2B%28influenza+flu%29&t=Swine+Flu&f=infectiousdiseases&r=Any&o=d" target ="_self">Swine Flu RSS news feed</a></b> - updated hourly from thousands of authoritative health and news sources.</p></div>
People With Asthma More Likely to Be Depressed
Title: People With Asthma More Likely to Be DepressedCategory: Health NewsCreated: 3/4/2010 12:10:00 PMLast Editorial Review: 3/5/2010 (Source: MedicineNet Diabetes General)
Major depression more than doubles risk of dementia among adults with diabetes
(University of Washington) Adults with both depression and diabetes are more than twice as likely to develop dementia compared to those with diabetes alone. Earlier studies have shown that depression alone is a risk factor for dementia, and that diabetes itself is a dementia risk factor. Researchers found even greater risk of dementia in people with both conditions. The mechanisms behind this increased risk are not yet clear. The researchers suggest that physicians screen and treat their diabetes patients for depression, which is common in people with diabetes. (Source: EurekAlert! - Social and Behavioral Science)
Dispatch: More Bureaucracy, Taxes, Stimulants, False Claims, Salmonella, and Asthma
As ACSH& #39;s Dr. Gilbert Ross wrote in yesterday& #39;s Washington Times, two senators have been attempting to turn criticism of one GlaxoSmithKline diabetes drug into an excuse to create an entire new drug-approval bureaucracy... (Source: Health Facts and Fears)
Diabetes education benefits 'sustained for years'
Benefits of a brief patient education programme are sustained for at least three years, a UK study suggests. (Source: HealthcareRepublic Independent Nurse News)
Diabetes could lead to reduced brain power
DIABETIC patients with sight problems could suffer from poorer memory and weakened brain power, Scottish research suggests. (Source: Scotsman.com News - Health)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Get the very latest Swine Flu news via the MedWorm <b><a href="http://www.medworm.com/rss/search.php?qu=%2Bswine+%2B%28influenza+flu%29&t=Swine+Flu&f=infectiousdiseases&r=Any&o=d" target ="_self">Swine Flu RSS news feed</a></b> - updated hourly from thousands of authoritative health and news sources.</p></div>
[Correspondence] White blood ? Authors' reply
Kinke Lommerse and colleagues respond to the case we presented of a woman on antiretroviral therapy (ART) in Malawi with untreated diabetes mellitus, extreme hyperlipidaemia, symptoms of peripheral neuropathy, and mild lipodystrophy. The focus of this report was that the clinical picture was a likely consequence of metabolic side-effects of stavudine and that relatively little is known about the epidemiology of these toxic effects in Africans. Secondarily, we pointed to logistical difficulties occurring with referrals in the overburdened health care system. (Source: LANCET)
[Case Report] Altered pain perception in schizophrenia
In June, 2009, a 51-year-old woman presented with a 4-day history of abdominal swelling and fever, and a 2-week history of loss of appetite. There was no history of abdominal pain or nausea. She was febrile (38·4°C) and her abdomen was swollen but soft without spontaneous pain or tenderness. She had a history of schizophrenia since the age of 40 years which was well controlled with perospirone 12 mg/day and quetiapine 150 mg/day. At the age of 45 years, she was diagnosed with diabetes mellitus and had achieved good glycaemic control (HbA1c 6·5%) with biphasic insulin aspart 30 (6 U/day). There was no sign of obvious peripheral neuropathy. Laboratory test results showed normocytic anaemia (haemoglobin 95 g/L), leucocytosis (13·3×109/L) with neutrophilia (91·5%), high concentration of ...
Identifying women with severe angiographic coronary disease
Conclusions. Women referred for first diagnostic angiography have lower rates of severe CAD compared with men across all ages. Whilst conventional risk factors, age, sex, diabetes, smoking and hyperlipidaemia are primary determinants of CAD amongst women and men, CCS Class IV angina is more likely to be associated with severe CAD in women than men. (Source: Journal of Internal Medicine)
Rapid Assessment of Genetic Ancestry in Populations of Unknown Origin by Genome-Wide Genotyping of Pooled Samples
In this study, we were able to measure genetic ancestry in populations of mixed ancestry by genotyping pooled, rather than individual, DNA samples. This represents a rapid and inexpensive means for modeling genetic ancestry and thus could facilitate future association or population-genetic studies in populations of unknown ancestry for which whole-genome data do not already exist. (Source: PLoS Genetics)

blood sugar metabolism theory may have some validity.

To revisit, low glycemic foods are those that don't spike your blood sugar. They consist of proteins and complex carbohydrates, typically higher in fiber, that burn slowly and give you sustained energy release. We don't completely understand the reason why these foods would be good for acne treatment, but it seems to have something to do with insulin levels.

High glycemic diets spike insulin levels by spiking blood sugar. Insulin, in turn, affects a whole bunch of other hormones that are especially raging in teenagers and young adults and this appears to stimulate acne.

You don't need to understand all the nuts and bolts of the biology to get the benefit. The great thing is that this new data will arm you with some reasons to convince your teens to adopt a healthy low glycemic diet. They will probably care much more about eating foods that will help clean up their face now, than they will about preventing heart disease and in their forties and fifties. But paying attention to what they eat will help them now and later.

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